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Del Coso, J, Salinero, JJ, Lara, B, Gallo-Salazar, C, Areces, F, Herrero, D, and Puente, C. Polygenic profile and exercise-induced muscle damage by a competitive half-ironman. J Strength Cond Res 34(5): 1400-1408, 2020 To date, it is still unknown why some individuals develop higher levels of muscle damage than other individuals, despite participating in exercise with comparable levels of physical intensity. The aim of this investigation was to analyze 7 single-nucleotide polymorphisms (SNPs) that are candidates to explain individual variations in the level of muscle damage attained during a half-ironman competition. Using the model of Williams and Folland (2, 1, and 0 points for optimal, intermediate, and suboptimal genotype), we determined the total genotype score from the accumulated combination of 7 SNPs (ACE = 287bp Ins∕Del; ACTN3 = p.R577X; creatine kinase, muscle type = NcoI; insulin-like growth factor 2 = C13790G; interleukin-6 = 174G.C; myosin light chain kinase = C37885A; and tumor necrosis factor-a = 308G.A) in 22 experienced triathletes. Before and after the race, a sample of venous blood was obtained to measure serum markers of muscle damage. Two groups of triathletes were established according to their postcompetition serum CK concentration: low CK responders (n = 10; 377 ± 86 UL−1) vs. high CK responders (n = 12; 709 ± 136 UL−1). At the end of the race, low CK responders had lower serum myoglobin concentrations (384 ± 243 vs. 597 6 293 ngml−1, p = 0.04). Although the groups were similar in age, anthropometric characteristics, and training habits, total genotype score was higher in low CK responders than in high CK responders (7.7 ± 1.1 vs. 5.5 ± 1.1 point, p ,< 0.01). A favorable polygenic profile can contribute to reducing the level of muscle damage developed during endurance exercise [ABSTRACT FROM AUTHOR]

Dorsiflexion sport shoes aim to increase jumping capacity and speed by means of a lower position of the heel in comparison with the forefoot, favouring additional stretching of the ankle plantar flexors. In previous studies, contradictory results have been found on the benefits of using this type of shoe. With the aim of comparing a dorsiflexion sport shoe model (DF) with a conventional sport shoe (CS), 41 participants performed a countermovement jump (CMJ) test and an agility test (MAT) with both models of shoe. There were no significant differences in the jump test [CS=35.3 cm (6.4) and DF=35.6 cm (6.4), P>0.05]. In the agility test, the conventional shoe obtained better results than the model with dorsiflexion with regard to time taken to complete the circuit [CS=6236 ms (540) and DF=6377 ms (507), P<0.05)]. In spite of producing pre-stretching of the plantar muscles, the DF sport shoes were not effective for improving either jump power or agility in a specific test. [ABSTRACT FROM AUTHOR]

The aim of this study was to assess different physiological variables before and after a 5-km (women) and 10-km (men) cross-country skiing competition to determine potential mechanisms of fatigue. Fourteen elite-level skiers competed in an official cross-country skiing competition using the classical style (9 men and 5 women). Instantaneous skiing velocity was measured during the race by means of 15-Hz global positioning system devices. Before and after the race, a sample of venous blood was obtained to assess changes in blood lactate and serum electrolyte and myoglobin concentrations. Prerace to postrace changes in blood oxygen saturation, forced vital capacity during a spirometry test, jump height during a countermovement jump, and handgrip force were also measured. Mean race speed was 15.8 ± 2.5 and 15.4 ± 1.5 km⋅h-1, whereas mean heart rate was 171 ± 6 and 177 ± 3 b⋅min-1 for men and women, respectively. There were no significant prerace to postrace changes in jump height, handgrip force, and forced vital capacity in men and women. Blood oxygen saturation was reduced from prerace to postrace in men (95.9 ± 2.1% to 93.1 ± 2.3%, p = 0.02) and women (97.8 ± 1.1% to 92.4 ± 2.1%, p < 0.01), whereas blood lactate concentration increased at the end of the race in men (1.4 ± 0.5 to 4.9 ± 2.1 mmol⋅L-1, p < 0.01) and women (1.9 ± 0.1 to 6.9 ± 3.2 mmol⋅L-1, p < 0.01). After the race, blood markers of muscle damage were at low concentrations, whereas serum electrolytes remained unchanged. Fatigue in 5- and 10-km cross-country skiing competitions was related to a reduced blood oxygen carrying capacity and presumably increased muscle and blood acidosis, whereas the influence of exercise-induced muscle damage on fatigue was minor. [ABSTRACT FROM AUTHOR]