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Promoting customers' pro-environmental behaviors (PEBs) is crucial for greening the hotel industry. However, customers often hesitate to adopt resource-saving PEBs in public places like hotels due to a "dual positive externality/spillover" problem – extra positive economic spillovers and increased positive environmental spillovers, compared to conducting such behaviors in private households. This study explores habitual PEBs at home and two distinct environmental cognitions associated with key spillover beneficiaries (nature and hotels) to address this challenge and accelerate customers' PEBs in hotel settings. The rationale is that customers' habitual PEBs at home can automatically extend to hotels with insensitivity or low sensitivity to positive spillovers; the two beneficiary-linked environmental cognitions (general environmental awareness associated with nature and occasional corporate environmental responsibility attribution [CERA] linked to hotels) can make customers psychologically internalize the positive spillovers of their PEBs at home and hotels to different degrees by changing psychological boundaries between actors and beneficiaries, and/or enable them to realize the intrinsic psychological rewards or incentives (such as a sense of pride or identification) that serve as compensation for the spillovers. Furthermore, this study proposes that habitual PEBs at home mediate between general environmental awareness and PEBs at hotels by bridging the cognition-behavior gap. Moreover, there is a sequential decrease in the effects of habitual PEBs at home, altruistic CERA, and environmental awareness on PEBs at hotels. Empirical evidence from a survey of Chinese hotel guests supports most hypotheses, offering valuable insights for promoting PEBs in the hotel industry. [ABSTRACT FROM AUTHOR]

Technological spillover – the transfer and use of knowledge between defence and civilian sectors – is desired by many countries, and particularly salient under intensifying US-China competition. Yet to date, no systematic measure of spillover exists. This paper presents a novel measure of spillover using a dataset of over 116,000 defence-related patents, and argues that (1) concerns over China’s ‘authoritarian advantage’ should be moderated, and (2) the composition and structure of knowledge transfer networks in the US and China should inform the appropriate channels of managing competition, which I demonstrate through case studies of aerial drones and missile technology spillover networks. [ABSTRACT FROM AUTHOR]

Decision models for economic evaluation are increasingly including health-related quality of life (HRQoL) for informal/unpaid carers, but these estimates often come from poor quality data and typically rely on cross-sectional analysis. We aimed to identify within-person effects using longitudinal analysis of 13 waves of Understanding Society (the UK Household Longitudinal Survey). We analyzed data for coresident carer and care-recipient dyads, where the carer reported "looking after or giving special help to" the care recipient in any of the 13 waves. We used fixed-effects models to study the effects of caring for the care recipient (the "caregiving" effect) using volume of care (hours per week) and continuous duration of caregiving (years) and caring about the care recipient (the "family" effect) using the care recipient's HRQoL on the carer's HRQoL. HRQoL was measured using the Short Form 6 Dimension, calculated from the Short Form 12. We found consistent evidence for the family effect: improving care recipient's HRQoL by 0.1 would improve carer's HRQoL by approximately 0.012. We also consistently found evidence of a small but statistically significant decrement to carer's HRQoL for each additional year of caring. These findings were robust to scenario analyses. Evidence for the relationship between volume of care and carer's HRQoL was less clear. We propose that our estimates can be used to populate economic models to predict changes in carers' HRQoL over time and allow disutilities to be estimated separately for the family and caregiving effect. • Much evidence for the relationship between informal/unpaid caring and health-related quality of life (HRQoL) relies on analysis of cross-sectional data, but we identify within-person effects using longitudinal data. • Carers' HRQoL declines as the duration of caring increases (the "caregiving" effect) and declines as care recipient's HRQoL declines (the "family" effect"). • Our findings can be used in economic evaluations to estimate carers' HRQoL changes from patient HRQoL changes and caring duration. [ABSTRACT FROM AUTHOR]

Prairie dogs are notoriously difficult to enumerate, with previously methods including visual counts, mark‐resight, burrow counts, and catch per unit effort. Unlike those methods, spatial capture‐recapture (SCR) analyses allow for formal estimation of density along with associated estimates of uncertainty, detection probability, and the size of the average area over which an individual was detected during the study period (referred to as an activity center). Using SCR analyses, we compared density estimates as part of a field trial evaluating the effectiveness of an oral sylvatic plague vaccine in black‐tailed prairie dogs (Cynomys ludovicianus), Gunnison's prairie dogs (C. gunnisoni), white‐tailed prairie dogs (C. leucurus), and Utah prairie dogs (C. parvidens) at 11 study areas in the western United States. The study was designed as a matched pairs analysis that included 27 individual paired plots (54 plots), each consisting of a plot treated with vaccine baits and a plot treated with placebo baits. Overall, we captured >3,000 individuals each year on these plots, and recapture rates ranged from 5–87%. For black‐tailed prairie dogs, density estimates ranged from 2.7 individuals/ha (95% CI = 2.2–3.3/ha) to 77.3/ha (63.2–94.4/ha), and for Gunnison's prairie dogs, estimates ranged from 11.7/ha (10.6–12.8/ha) to 15.4/ha (14.4–16.7/ha). White‐tailed prairie dogs were at their lowest density (3.3/ha, 95% CI = 2.9–3.8/ha) during the first year of the study and their highest density (14.5/ha; 13.5–15.6/ha) during the last year of the study. Utah prairie dog density estimates ranged from a low of 4.0/ha (95% CI = 3.55–4.6/ha) to a high of 20.8/ha (16.8–25.8/ha). Best‐fitting models of prairie dog density indicated increasing patterns of density over time on most study plots, negative effects of plague, and positive effects of vaccination. Finally, we found low correlations between catch per unit effort estimates from previous published literature at these sites and our densities estimates. Spatial capture‐recapture estimates allowed us to consistently compare treatment effects across space and time, although some exceptions are noted where we observed significant movement between plots within a pair (3 pairs) and when trapping effort between plots or years was not consistent. [ABSTRACT FROM AUTHOR]

Electoral shocks have spillover effects in democracies, as they can change citizens' political attitudes and political behaviour across national borders. Yet, electoral shocks also exist in non-democratic regimes. Do electoral shocks likewise lead to spillover within a non-democratic regime? To explore this question, I build on Lohmann's idea of information cascade and study the spillover of the 2019 Hong Kong local election, in which the opposition won a landslide victory. Using a survey fielded in Macau during this event, I find liberalizing effects among middle-class citizens: after the electoral shock, their democratic commitment increases while their perceived electoral fairness decreases. Conversely, lower-class citizens experience backlash effects as they assess the electoral system more positively and briefly consider democracy as less important. However, these changes in political attitudes do not translate into changes in expressed vote choice and other types of political participation. Regarding the mechanism of the attitudinal change, I suggest such polarized reactions are related to the different information consumption among the two classes. I discuss how these findings contribute to the literature on non-democratic regimes, electoral shocks, and class politics. [ABSTRACT FROM AUTHOR]

In many advanced catalytic materials, different functionalities are coupled through spillover of active species across heterogeneous interfaces. In the present work, we consider the coupling of a C─C bond cleavage functionality of palladium with the self‐cleaning functionality of reducible Co3O4. On the model catalyst Pd/Co3O4(111)/Ir(100), we probed the interplay of the two functionalities for the selective decomposition of ethanol. In a systematic study, we compared the decomposition mechanisms of ethanol on Co3O4(111)/Ir(100) and Pd/Co3O4(111)/Ir(100) model catalysts using a variety of analytical techniques including synchrotron radiation photoelectron spectroscopy (SRPES), resonant photoemission spectroscopy (RPES), temperature programmed desorption (TPD), and near ambient pressure X‐ray photoelectron spectroscopy (NAP‐XPS). We found that ethanol decomposes via an ethoxy intermediate yielding acetaldehyde on Co3O4(111)/Ir(100). Remarkably, the spillover of ethanol/ethoxy species on Pd/Co3O4(111)/Ir(100) results in the selective formation of methane, hydrogen, and CO. Additionally, we observed CO2 resulting from the oxidative removal of carbonaceous deposits on Pd nanoparticles via spillover of active oxygen species released by Co3O4(111)/Ir(100) at higher temperatures. The onset of product formation and the product spectrum on both Co3O4(111)/Ir(100) and Pd/Co3O4(111)/Ir(100) depend strongly on the oxidation state of Co3O4. Complete removal of lattice oxygen from Co3O4(111) results in the deposition of large amounts of carbon. [ABSTRACT FROM AUTHOR]

Emerging scholarship on Ukraine’s wartime European integration and the EU’s reinvigorated enlargement policy have been marked by the focus on intergovernmental matters and member states’ foreign policy coordination. This article challenges this view. First, relying on the neofunctionalist lens, it introduces the notion of a ‘super-spillover’ effect to explain the wartime intensification of Ukraine’s European integration and the plans for Ukraine’s gradual EU accession. It illustrates this notion with the case of Ukraine’s Single Market integration. Second, while reaffirming the neofunctionalism’s usefulness for explaining partner countries’ Single Market integration and EU enlargement under crises, the article points to several weaknesses of the neofunctionalist approach. They include the vagueness of the ‘geographical spillover’ concept and the lack of theorisation as to the sequencing of and the interplay between various spillover logics under crises. It thus contributes to the scholarship on neofunctionalism, EU enlargement policy, Single Market integration and EU-Ukraine relations. [ABSTRACT FROM AUTHOR]

Dispersal of propagules (seeds, spores) from a geographically isolated habitat into an uninhabitable matrix can play a decisive role in driving population dynamics. ODE and integrodifference models of these dynamics commonly feature a “dispersal success” parameter representing the average proportion of dispersing propagules that remain in viable habitat. While dispersal success can be estimated by empirical measurements or by integration of dispersal kernels, one may lack resources for fieldwork or details on dispersal kernels for numerical computation. Here we derive simple upper bounds on the proportion of propagule loss—the complement of dispersal success—that require only habitat area, habitat perimeter, and the mean dispersal distance of a propagule. Using vector calculus in a probabilistic framework, we rigorously prove bounds for the cases of both symmetric and asymmetric dispersal. We compare the bounds to simulations of integral models for the population of Asclepias syriaca (common milkweed) at McKnight Prairie—a 14 hectare reserve surrounded by agricultural fields in Goodhue County, Minnesota—and identify conditions under which the bounds closely estimate propagule loss. [ABSTRACT FROM AUTHOR]

Based on emotional security, stress, and spillover and crossover theories, this study aimed to examine the indirect pathways between destructive and constructive interparental conflict, parenting stress, unsupportive parenting, and child insecurity six months later. Using data from two time points beginning when Korean children (N = 159) were approximately 3–5 years old, two dual-mediation models of the relevant variables were constructed. The results indicate that destructive conflict is associated with higher levels of parenting stress, whereas constructive conflict is associated with lower levels of stress. Furthermore, mothers' and fathers' parenting stress influenced their own unsupportive parenting behaviors, which, in turn, influenced their children's insecurity, suggesting a spillover effect. However, the crossover effect and mediation analyses provided partial support for various pathways of the hypotheses. By examining both destructive and constructive conflict, including both maternal and paternal variables, and examining not only spillover but also crossover effects, this study highlights that while constructive conflict may reduce parental stress and unsupportive parenting behaviors, the negative effects of destructive conflict may affect children more strongly. Particularly, by examining the spillover and crossover effects in the unique cultural context of Korean families, this study provides important insights into interparental conflict's impact on child development. [ABSTRACT FROM AUTHOR]

Digital technologies have eroded the physical and psychological boundaries that divide work versus family. As a result, a new set of skills is necessary to manage digital interferences. We use individual-level data (n = 15,049) from the 2020/22 European Social Survey of 31 countries to examine the influence of digital job demands (e.g. digital work contact) and resources (e.g. digital skills) on work-to-family spillover, which occurs when behaviors and emotions from work intrude into the family. Aligned with prior research, hierarchical linear regressions demonstrate that the demands of digital work contact (e.g. work-related emails) exacerbate work-to-family spillover, while remote work is a resource reducing spillover. We advance these insights, however, revealing digital skills as an important boundary management resource. Digital skills not only reduce work-to-family spillover but also moderate the relationships that digital work contact and remote work have with work-to-family spillover. Drawing on a job demand-resource model, we suggest that digital skills are an important, yet understudied, resource for managing the boundary permeability and flexibility afforded by work-related technologies. Given that work-to-family spillover is a stressor linked to job satisfaction and family well-being, results highlight the potential of digital skills to alleviate inequalities in work and family outcomes. [ABSTRACT FROM AUTHOR]

Aim: Changes in landscape configuration significantly impact ecosystems and the services they provide, including disease regulation for both humans and wildlife. Land use conversion usually favors disturbed‐adapted species, which are often known reservoirs of zoonotic parasites, thereby potentially escalating spillover events (i.e., the transmission of parasites to new hosts, including humans). Here we aimed to investigate how alterations in landscape use and configuration influence the distribution and co‐occurrence of potential hosts of zoonotic and epizootic parasites. Location: Brazilian Atlantic Forest. Time Period: Data collection spanned from 1997 to 2019. Major taxa studied small mammals. Methods: We integrated ecological network metrics and joint distribution models while accounting for phylogenetic relationships and functional traits to answer two main questions: (1) do small mammal species considered central hosts in the transmission of parasites exhibit a higher probability of occurrence in landscapes with reduced native vegetation areas? (2) Do small mammal hosts that share a higher number of parasites have higher co‐occurrence probabilities? Results: Our results demonstrated that species identified as significant hosts in our centrality network analysis displayed an increased probability of occurrence in landscapes that are both more fragmented and have a higher proportion of farming areas, hence fewer native vegetation areas. Regarding the relationship between species co‐occurrence and parasite sharing, our findings indicated that most strong co‐occurrences were prevalent within groups with higher parasite fauna similarity, but not all species sharing parasites had a higher probability of co‐occurring. Conclusions: Here we highlight the effects of landscape conversion on small mammal species, including how different configurations of land use can influence both central and non‐central host occurrences. Besides, our results also indicate that parasite transmission may be overestimated when the co‐occurrence probability of potential host species is not considered. We highly recommend incorporating co‐occurrence data to estimate zoonotic risk. [ABSTRACT FROM AUTHOR]

The present study aimed to investigate the episodes of per-acute mortality due to peste des petits ruminants (PPR) that resulted in the death of 30 animals of different species of cervids, namely, barking deer, four-horned antelope, hog deer, thamin, and mouse deer in the State Zoo of Assam, a northeastern state of India. The affected animals showed no to limited clinical signs. However, the necropsy and histopathological findings were highly suggestive of PPR virus (PPRV) infection observed in domestic small ruminants. Representative tissue samples were screened for the presence of PPRV along with blue tongue virus (BTV) and epizootic hemorrhagic disease virus (EHDV) using RT-PCR or RT-qPCR and were found to be positive for PPRV. Considering the sudden outbreak of PPR in captive cervids, we sought to determine the role of domestic goats as the potential spillover host. To verify that, archived tissue samples of domestic goats collected during PPRV outbreaks in nearby localities and slaughtered goats used as meat for Carnivorous animals in the State Zoo were also screened and found to be positive for PPRV in RT-PCR. Phylogenetic analysis based on the Nucleocapsid (N) protein gene of PPRV from infected cervids, domestic goats, and goat meat revealed the virus to be of Lineage IV origin. Our findings provide evidence of probable spillover of PPRV from domestic goats to captive endangered cervids and circulation of Lineage IV PPRV strains among the small-ruminant population of this region. [ABSTRACT FROM AUTHOR]

Ticks are crucial vectors for various pathogens associated with human and animal diseases, including viruses. Nevertheless, significant knowledge gaps prevail in our understanding of tick-borne viruses (TBVs). We here examined existing studies on TBVs, uncovering 870 documented virus species across 28 orders, 55 families, and 66 genera. The discovery history, vector ticks, and hosts of TBVs, as well as the clinical characteristics of TBV-induced diseases, are summarized. In total, 176 tick species from nine tick genera were confirmed as vectors for TBVs. Overall, 105 TBVs were associated with infection or exposure to humans and animals. Of them, at least 40 were identified to cause human or animal diseases. This review addresses the current challenges associated with TBV research, including the lack of knowledge about the identification of novel and emerging TBVs, the spillover potentials from ticks to hosts, and the pathogenicity and infection mechanisms of TBVs. It is expected to provide crucial insights and references for future studies in this field, while specifically focusing on expanding surveys, improving TBV identification and isolation, and enhancing the understanding of TBV–vector–host interactions. All of these findings will facilitate the preparation for preventing and treating diseases caused by emerging and novel TBVs. [ABSTRACT FROM AUTHOR]

Spillover from interparental conflict (IPC) to the parent–child relationship is a risk factor for adolescent emotional, social, and behavioral maladjustment. Parental depression increases the risk for more frequent and intense IPC over periods of months to years, but relatively little is known about whether parental depressive symptoms increase the risk for IPC and/or the propensity for spillover on short timescales. Using daily diary methods, we tested two hypotheses to evaluate whether parental depressive symptoms predict increased risk for IPC spillover: (a) a stress generation hypothesis, in which higher levels of parental depressive symptoms are associated with a greater tendency to experience IPC, which elevates risk for spillover, and (b) a spillover propensity hypothesis, in which parental depressive symptoms strengthen the within-person linkage between daily couple conflict and poorer parent–adolescent relations. We analyzed data from 150 adolescents and caregivers from two-caregiver families who completed baseline and 21-day daily diary surveys. Consistent with a stress generation hypothesis, parents who were higher in baseline depressive symptoms reported higher levels of IPC over 21 days. At the daily level, there was evidence of spillover from IPC to higher parent–adolescent conflict and lower parent–adolescent closeness, but there was no evidence for increased propensity for spillover by parents' baseline depressive symptoms or daily depressed mood. Rather, there was a direct association between higher daily parental depressed mood and poorer daily parent–adolescent relationship quality (lower closeness, higher conflict). Ameliorating parental depressive symptoms may improve parent–adolescent relationship quality directly, as well as indirectly by decreasing the risk for IPC. [ABSTRACT FROM AUTHOR]

This study took a family systems perspective and tested spillover theory to examine the transmission of stress from parents to children during COVID-19. Using a longitudinal design with a 1-year interval, we tested the association between parent perceived stress and perceived child stress, and the sequential mediating effects of poor family functioning and parent–child closeness. The data comprised 134 parents residing in the US who were assessed from the initial first peak of COVID-19 infections in 2020 to 2021, 1 year later. Results indicated that when controlling for covariates, there was a significant association between parent perceived stress and perceived child stress. What is more, poor family functioning and parent–child closeness fully mediated the former link in sequence. These findings highlighted the need for improving family relationship quality when providing interventions that target families suffering in stressful contexts. [ABSTRACT FROM AUTHOR]

Intensive agricultural land use negatively impacts biodiversity, including arthropod predator diversity and their pest control potential. Alley‐cropping agroforestry systems (integration of tree rows into arable land) are increasingly considered an economically viable alternative for more sustainable and biodiversity‐friendly agriculture. However, their effectiveness in promoting generalist predator diversity and pest control, especially as a function of space (distance from tree rows) and time (across the growing season) remains poorly understood.We assessed how spider abundance, taxonomic and functional diversity (as proxies of pest control potential) respond to temperate alley‐cropping agroforestry systems as compared to open croplands. Additionally, we analysed whether spiders with different habitat preferences (eurytopic, forest and open‐habitat specialists) show distinct responses. Lastly, we analysed whether the influence of agroforestry changes with decreasing tree proximity and across the growing season.Tree row proximity generally benefited the abundance, as well as taxonomic and functional diversity of the overall spider communities. Alley‐cropping promoted the abundance and taxonomic diversity of forest specialists and eurytopic spiders, without negatively affecting open‐habitat specialists. The positive effect of alley cropping was strongest within tree rows and their immediate vicinity, but was still detectable at considerably farther distances. These patterns were temporally dynamic with spider abundance and taxonomic diversity being highest within tree rows in early spring and spiders spilling over to adjacent crop rows in subsequent periods.Synthesis and applications: Overall, our findings highlight that the inclusion of tree rows benefited spiders across the entirety of the 48 m crop rows, independent of crop type. Since the peak in spider abundance and taxonomic diversity in crop rows coincided with crop pest arrival, alley‐cropping agroforestry is expected to benefit agricultural production through increased pest control potential. Alley‐cropping agroforestry may therefore be an important management strategy to develop more sustainable agricultural systems benefiting farmers and biodiversity alike. [ABSTRACT FROM AUTHOR]

Background The risk of antibiotic resistance is complicated by the potential for spillover effects from one treated population to another. Azithromycin mass drug administration programs report higher rates of antibiotic resistance among treatment arms in targeted groups. This study aimed to understand the risk of spillover of antibiotic resistance to nontarget groups in these programs. Methods Data were used from a cluster-randomized trial comparing the effects of biannual azithromycin and placebo distribution to children 1–59 months old on child mortality rates. Nasopharyngeal samples from untreated children 7–12 years old were tested for genetic determinants of macrolide resistance (primary outcome) and resistance to other antibiotic classes (secondary outcomes). Linear regression was used to compare the community-level mean difference in prevalence by arm at the 24-month time point, adjusting for baseline prevalence. Results A total of 1103 children 7–12 years old in 30 communities were included in the analysis (15 azithromycin, 15 placebo). The adjusted mean differences in the prevalence of resistance determinants for macrolides, β-lactams, and tetracyclines were 3.4% (95% confidence interval, −4.1% to 10.8%; P =.37), −1.2% (−7.9% to 5.5%; P =.72), and −3.3% (−9.5% to 2.8%; P =.61), respectively. Conclusions We were unable to demonstrate a statistically significant increase in macrolide resistance determinants in untreated groups in an azithromycin mass drug administration program. While the result might be consistent with a small spillover effect, this study was not powered to detect such a small difference. Larger studies are warranted to better quantify the potential for spillover effects within these programs. [ABSTRACT FROM AUTHOR]

Home range size is a fundamental trait that can affect the probability of fish being harvested and, at the same time, may be affected by fishing. The relationship between home range size and fishing will impact the effectiveness of fully protected areas (FPAs), as it will influence the number of fish moving into fished areas, affecting both spillover and edge effects. One hypothesis is that individuals within FPAs will present reduced home range size relative to individuals in fished areas. This pattern can be driven by demographic selection (e.g. fishing of individuals with large home ranges leaving the FPAs), improved habitat requiring less foraging movements, or behavioural changes associated with reduced fishing threats. To test the relationship between home range size and protection, we compiled 1143 individual‐level home range sizes based on acoustic tracking, covering 17 species from 11 FPAs in 7 countries, with information on distance from FPA borders. A dichotomic analysis (in/out of FPAs) did not support a significant change in the home range size between FPAs and fished areas. However, continuous analysis across the FPA borders demonstrated reduced home range size within the FPAs. We did not find an effect of FPA age or size on this pattern. While we cannot pinpoint the underlying mechanism for the pattern revealed, we suggest behavioural changes as the main driver for reduced home range within FPAs. This mechanism will lead to more resident populations within FPAs, reducing fishing mortality within FPAs yet limiting spillover benefits to adjacent fisheries. [ABSTRACT FROM AUTHOR]

Simple Summary: This work provides an overview on the impact of bats' diet on their intestinal microorganism community and its influence on potential pathogenicity. Human expansion generates natural habitat alterations, which force bats to seek alternative sites, leading to contact with other animals, including humans. Exploring the relationship between the dietary habits of bats and the variety of their microbiome could contribute elucidating the potential role of bats as reservoirs of multidrug-resistant microorganisms and their implications in the dissemination of mutating viruses and antibiotic-resistant bacteria in the environment and possibly in their transmission to human and to domestic and wild animals. In this review, we tentatively tried to connect the most recent findings on the bat microbiome and to investigate on their microbial communities, that may vary even in conspecific hosts and are influenced by host physiology, feeding behavior and diet, social interactions, but also by habitat diversity and climate change. From a conservation perspective, understanding the potentially negative and indirect effects of habitat destruction on animal microbiota can also play a crucial role in the conservation and management of the host itself. According to the One Health concept, which recognizes an interdependence between humans, animals, and the environment, bat microbiota represents an indicator of host and environmental health, besides allowing for evaluation of the risk of emerging infectious diseases. We noticed that a growing number of studies suggest that animal microbiota may respond in various ways to changes in land use, particularly when such changes lead to altered or deficient food resources. We have highlighted that the current literature is strongly focused on the initial phase of investigating the microbial communities found in Chiroptera from various habitats. However, there are gaps in effectively assessing the impacts of pathogens and microbial communities in general in animal conservation, veterinary, and public health. A deeper understanding of bat microbiomes is paramount to the implementation of correct habitat and host management and to the development of effective surveillance protocols worldwide. [ABSTRACT FROM AUTHOR]

As exotic plants invade into a new range, they can escape from specialist enemies. However, they may support generalist enemies, including both native and introduced fungal pathogens, which creates the potential for spillover and apparent competition from exotic to native plants in communities.To assess the potential for spillover of putatively pathogenic, root‐associated fungi (hereafter, 'pathogens') in communities invaded by exotic plants, we conducted a two‐phase plant–soil feedback experiment: a monoculture experiment with native and exotic plants grown alone and a multi‐species, community‐level experiment that ranged in the extent of exotic dominance. We used next‐generation sequencing to characterise sharing of pathogens between native and exotic plants in communities.Exotic plants outperformed natives in communities, despite harbouring higher relative abundance of generalist pathogens. The higher generalism of pathogens supported by exotic plants made them more prone to be shared with natives. The proportion of pathogens shared between exotic and native plants in communities correlated with reduced competitive ability of native compared with exotic plants.Synthesis: These data suggest that exotic plants host more generalist pathogens that are shared with native plants, which may confer an indirect benefit to exotic over native plants through apparent competition. [ABSTRACT FROM AUTHOR]

The emergence of new diseases is an urgent concern, but hosts can also vary in resistance to pathogens that are novel to them, facilitating evolutionary rescue. However, little is known about the genetic source for polymorphic resistance to novel pathogens or its relationship to defences against endemic diseases. With anther‐smut disease from wild plant populations, we used selection experiments and genetic analyses to show that resistances to novel and endemic pathogens are genetically independent, despite being positively correlated in nature. Moreover, novel‐pathogen resistance presented a much simpler genetic basis and more rapid response to selection. We demonstrate that polymorphic resistance to a newly introduced disease is genetically determined and not an extension of defences against the related endemic pathogen, challenging the conventional view of nonhost resistance. [ABSTRACT FROM AUTHOR]

Interactions between wildlife and livestock can lead to cross‐species disease transmission, which incurs economic costs and threatens wildlife conservation. Wild waterfowl are natural hosts of avian influenza viruses (AIVs), are often abundant near poultry farms, and have been linked to outbreaks of AIVs in poultry. Interspecific and seasonal variation in waterfowl movement and habitat use means that the risk of disease transmission between wild birds and poultry inevitably varies across species, space, and time. Here, we used GPS telemetry data from 10 waterfowl species in and near California's Central Valley, a region where both wild waterfowl and domestic poultry are abundant, to study selection of poultry farms by waterfowl across diel, seasonal, and annual cycles. We found that waterfowl selected for wetlands, open water, protected areas, and croplands, which meant that they generally avoided habitats that were likely to be used for poultry farming. These selection patterns were linked to species' ecology and diel behavioral patterns, such that avoidance of poultry habitats was stronger for local or partial migrants than for long‐distance migrants, and stronger during daytime than at night. We then combined these habitat selection results with data on poultry farm locations to map risk of waterfowl–poultry contact across the Central Valley. Average selection strength at poultry farms was low, suggesting that current placement of poultry farms is generally effective for limiting risk of contact with wild birds. When we combined these habitat selection results with data on species' abundances and AIV infection prevalence, we found dramatic variation in potential AIV transmission risk among species. These results could be used to prioritize surveillance and biosecurity efforts for regions and times of relatively high risk. More generally, these results highlight that fine‐scale movement data can help identify interspecific, seasonal, and diel patterns in animal behaviors that affect wildlife and poultry health. [ABSTRACT FROM AUTHOR]

Bat‐borne pathogens are a threat to global health and in recent history have had major impacts on human morbidity and mortality. Examples include diseases such as rabies, Nipah virus encephalitis, and severe acute respiratory syndrome (SARS). Climate change may exacerbate the emergence of bat‐borne pathogens by affecting the ecology of bats in tropical ecosystems. Here, we report the impacts of climate change on the distributional ecology of the common vampire bat Desmodus rotundus across the last century. Our retrospective analysis revealed a positive relationship between changes in climate and the northern expansion of the distribution of D. rotundus in North America. Furthermore, we also found a reduction in the standard deviation of temperatures at D. rotundus capture locations during the last century, expressed as more consistent, less‐seasonal climate in recent years. These results elucidate an association between D. rotundus range expansion and a continental‐level rise in rabies virus spillover transmission from D. rotundus to cattle in the last 50 years of the 120‐year study period. This correlative study, based on field observations, offers empirical evidence supporting previous statistical and mathematical simulation‐based studies reporting a likely increase of bat‐borne diseases in response to climate change. We conclude that the D. rotundus rabies system exemplifies the consequences of climate change augmentation at the wildlife–livestock–human interface, demonstrating how global change acts upon these complex and interconnected systems to drive increased disease emergence. [ABSTRACT FROM AUTHOR]

Spillover of adsorbed species from one active site to another is a key step in heterogeneous catalysis. However, the factors controlling this step, particularly the spillover of polyatomic species, have rarely been studied. Herein, we investigate the spillover dynamics of H* and CH3* species on a single‐atom alloy surface (Rh/Cu(111)) upon the dissociative chemisorption of methane (CH4), using molecular dynamics that considers both surface phonons and electron‐hole pairs. These dynamical calculations are made possible by a high‐dimensional potential energy surface machine learned from density functional theory data. Our results provide compelling evidence that the H* and CH3* can spill over on the metal surface at experimental temperatures and reveal novel dynamical features involving an internal motion during diffusion for CH3*. Increasing surface temperature has a minor effect on promoting spillover, as geminate recombinative desorption becomes more prevalent. However, the poisoning of the active site can be mitigated by the frequent gaseous molecular collisions that occur under ambient pressure in real‐world catalysis, which transfer energy to the trapped adsorbates. Interestingly, the bulky CH3* exhibits a significant spillover advantage over the light H* due to its larger size, which facilitates energy acquisition. These insights help to advance our understanding of spillover in heterogeneous catalysis. [ABSTRACT FROM AUTHOR]

Spillover of adsorbed species from one active site to another is a key step in heterogeneous catalysis. However, the factors controlling this step, particularly the spillover of polyatomic species, have rarely been studied. Herein, we investigate the spillover dynamics of H* and CH3* species on a single‐atom alloy surface (Rh/Cu(111)) upon the dissociative chemisorption of methane (CH4), using molecular dynamics that considers both surface phonons and electron‐hole pairs. These dynamical calculations are made possible by a high‐dimensional potential energy surface machine learned from density functional theory data. Our results provide compelling evidence that the H* and CH3* can spill over on the metal surface at experimental temperatures and reveal novel dynamical features involving an internal motion during diffusion for CH3*. Increasing surface temperature has a minor effect on promoting spillover, as geminate recombinative desorption becomes more prevalent. However, the poisoning of the active site can be mitigated by the frequent gaseous molecular collisions that occur under ambient pressure in real‐world catalysis, which transfer energy to the trapped adsorbates. Interestingly, the bulky CH3* exhibits a significant spillover advantage over the light H* due to its larger size, which facilitates energy acquisition. These insights help to advance our understanding of spillover in heterogeneous catalysis. [ABSTRACT FROM AUTHOR]

High pathogenicity avian influenza virus (HPAIV) is a rapidly evolving virus causing significant economic and environmental harm. Wild birds are a key viral reservoir and an important source of viral incursions into animal populations, including poultry. However, we lack a thorough understanding of which species drive incursions and whether this changes over time. We explored associations between the abundances of 152 avian species and outbreaks of highly pathogenic avian influenza (HPAI) in poultry premises across Great Britain between October 2021 and January 2023. Spatial generalized additive models were used, with species abundance distributions sourced from eBird. Associations were investigated at the species-specific level and across species aggregations. During autumn/winter, associations were generally strongest with waterbirds such as ducks and geese; however, we also found significant associations in groups such as non-native gamebirds and rapid change in species-specific associations over time. Our results demonstrate the value of citizen science to rapidly explore wild species as potential facilitators of disease incursions into well-monitored populations, especially in regions where viral surveillance in wild species is limited. This can be a critical step towards prioritizing targeted surveillance that could inform species-specific biosecurity measures; particularly for HPAIV, which has undergone sudden shifts in host range and continues to rapidly evolve. [ABSTRACT FROM AUTHOR]

We introduce a new class of measures called spatial population concentration (SPC) designed to quantify how many people live on average within a given radius of every person within a geographic area. The distinguishing feature relative to existing measures is that ours are the first to satisfy scale invariance, replication invariance, sensitivity to transfers, aggregativity, sensitivity to neighborhoods, invariance to uninhabited regions, concurrently. We calculate the SPC measure at the US county level for various radii and identify that the strongest relationship with subsequent economic growth can be found for a 25‐km radius. Interacting SPC with diverse infrastructure metrics does not alter the optimal radius. This indicates that regional policies such as infrastructure projects which influence density should strategically target the 25‐km distance range to maximize the growth impact. We also show that the importance of SPC has declined over time. [ABSTRACT FROM AUTHOR]

Communal violence is a major source of insecurity within and across borders, sparking significant displacement flows and disturbing livelihoods. While conflict literature has shed light onto its causes, the existing research has paid little systematic attention to the spatial dynamics of communal violence. We distinguish between spillover of violence and spillover of predictors. Spillover of violence is defined as conflict incidences occurring as a direct response to communal violence in a nearby location. Spillover of predictors describes instances of communal violence that occur due to nearby conflict-inducing factors. We clarify theoretical pathways for both spillover processes, focusing on drought exposure affecting not locally but in nearby areas. Applying spatial models, we test the expectations regarding nearby violence breeding violence and nearby drought increasing violence with data on incidences of communal violence for sub-Saharan Africa (1990–2014). Our results demonstrate that communal violence explains nearby communal violence through different spillover processes. We also find evidence for an increase in violence due to exposure from neighborhood droughts as well as other conflict-inducing factors. [ABSTRACT FROM AUTHOR]

Amid the SARS-CoV-2 pandemic, concerns surfaced regarding the spread of the virus to wildlife. Switzerland lacked data concerning the exposure of free-ranging animals to SARS-CoV-2 during this period. This study aimed to investigate the potential exposure of Swiss free-ranging wildlife to SARS-CoV-2. From 2020 to 2023, opportunistically collected samples from 712 shot or found dead wild mustelids (64 European stone and pine martens, 13 European badgers, 10 European polecats), canids (449 red foxes, 41 gray wolves, one golden jackal) and felids (56 Eurasian lynx, 18 European wildcats), as well as from 45 captured animals (39 Eurasian lynx, 6 European wildcats) were tested. A multi-step serological approach detecting antibodies to the spike protein receptor binding domain (RBD) and N-terminal S1 subunit followed by surrogate virus neutralization (sVNT) and pseudotype-based virus neutralization assays against different SARS-CoV-2 variants was performed. Additionally, viral RNA loads were quantified in lung tissues and in oronasal, oropharyngeal, and rectal swabs by reverse transcription polymerase chain reactions (RT-qPCRs). Serologically, SARS-CoV-2 exposure was confirmed in 14 free-ranging Swiss red foxes (prevalence 3.1%, 95% CI: 1.9–5.2%), two Eurasian lynx (2.2%, 95% CI: 0.6–7.7%), and one European wildcat (4.2%, 95% CI: 0.2–20.2%). Two positive foxes exhibited neutralization activity against the BA.2 and BA.1 Omicron variants. No active infection (viral RNA) was detected in any animal tested. This is the first report of SARS-CoV-2 antibodies in free-ranging red foxes, Eurasian lynx, and European wildcats worldwide. It confirms the spread of SARS-CoV-2 to free-ranging wildlife in Switzerland but does not provide evidence of reservoir formation. Our results underscore the susceptibility of wildlife populations to SARS-CoV-2 and the importance of understanding diseases in a One Health Concept. [ABSTRACT FROM AUTHOR]

Non‐crop (segetal) plants in arable systems are commonly perceived simply as 'weeds', that is, harmful at worst and undesirable at best. The increase in management intensity in European arable systems has vastly reduced the populations of all but the most disturbance‐tolerant plant species, negatively impacting the whole agricultural food web. In recent years, efforts have been made to promote agricultural biodiversity through measures such as flower strips and unsprayed field margins. However, studies of their impacts on the arable flora have rarely considered their spatial variation within the crop field.We investigated the spatial distribution of vascular plant species richness and their contribution to the food web via biomass and flower units in conventional and agri‐environment cereal fields in six regions of Germany. We studied two types of in‐crop measures (extensive cereals without pesticides or fertiliser, and with or without intercropping with flowering species) and one adjacent measure (neighbouring flower strip), recording at 1‐m intervals from the field edge to the interior. These results were then extrapolated to illustrate the effects of these measures on resource provision at the field scale.Species richness and plant biomass dropped off sharply after the first metre in the conventional treatments, regardless of the adjacent habitat. The 'extensive' treatments maintained a much higher level of diversity and resource provision in the field interior. At the field level, this can mean more than a 60‐fold difference in the provision of flowering resources between conventional management (1900 flower units/ha) and agri‐environment measures (AEMs) (127,000 units/ha for extensive cereals).Synthesis and applications. The strong edge effects we found in conventional cultivation support the premise that reducing field sizes could play a role in promoting in‐crop biodiversity. However, incorporating extensive field margins as an AEM would be more efficient at maximising the diversity of generalists whilst maintaining high yields. [ABSTRACT FROM AUTHOR]

Science is humanity’s best insurance against threats from nature, but it is a fragile enterprise that must be nourished and protected. The preponderance of scientific evidence indicates a natural origin for SARS-CoV-2. Yet, the theory that SARS-CoV-2 was engineered in and escaped from a lab dominates media attention, even in the absence of strong evidence. We discuss how the resulting anti-science movement puts the research community, scientific research, and pandemic preparedness at risk. [ABSTRACT FROM AUTHOR]

Background: Spillover of effect, whether positive or negative, from intervention to control group patients invalidates the Stable Unit Treatment Variable Assumption (SUTVA). SUTVA is critical to valid causal inference from randomized concurrent controlled trials (RCCT). Spillover of infection prevention is an important population level effect mediating herd immunity. This herd effect, being additional to any individual level effect, is subsumed within the overall effect size (ES) estimate derived by contrast-based techniques from RCCT's. This herd effect would manifest only as increased dispersion among the control group infection incidence rates above background. Methods and results: The objective here is to explore aspects of spillover and how this might be visualized and diagnosed. I use, for illustration, data from 190 RCCT's abstracted in 13 Cochrane reviews of various antimicrobial versus non-antimicrobial based interventions to prevent pneumonia in ICU patients. Spillover has long been postulated in this context. Arm-based techniques enable three approaches to identify increased dispersion, not available from contrast-based techniques, which enable the diagnosis of spillover within antimicrobial versus non-antimicrobial based infection prevention RCCT's. These three approaches are benchmarking the pneumonia incidence rates versus a clinically relevant range, comparing the dispersion in pneumonia incidence among the control versus the intervention groups and thirdly, visualizing the incidence dispersion within summary receiver operator characteristic (SROC) plots. By these criteria there is harmful spillover effects to concurrent control group patients. Conclusions: Arm-based versus contrast-based techniques lead to contrary inferences from the aggregated RCCT's of antimicrobial based interventions despite similar summary ES estimates. Moreover, the inferred relationship between underlying control group risk and ES is 'flipped'. [ABSTRACT FROM AUTHOR]

Non‐crop vegetation areas in agricultural landscapes are vital for maintaining biodiversity. However, they potentially host pest insects, which can cause economic loss in crop fields.Some insect species have been found to spill into crops from these areas, but this varies depending on species, landscape composition and the time of the season.To determine if five common pest insects of canola crops were spilling into fields during the late growing season, we collected samples at various distances from non‐crop areas, in a part of the Canadian Prairies (Alberta, Canada) where this crop is widely grown.Sampling occurred at 15 sites in each of 10 fields (N = 150 sites). We modelled changes in pest abundance over distance from the non‐crop areas and contrasted the abundance of each taxon in the crop and non‐crop areas.Only leafhoppers (Hemiptera: Cicadellidae) demonstrated a declining gradient in abundance that is consistent with spillover from non‐crop vegetation areas into the canola fields. Weevils were found to have significantly higher abundance in the non‐crop areas, indicating a relationship between this taxon and the non‐crop area in the late season, but there was no decline in abundance, which might indicate spillover occurring. All taxa demonstrated spatial differences in abundance among fields.This study found limited evidence that the pests are spilling over from non‐crop vegetation into canola crops during the late season. Therefore, movement of pests from non‐crop vegetation areas at this time is unlikely to be a driver of pest pressure for this economically important crop. [ABSTRACT FROM AUTHOR]

This study investigates the interdependent structure between Nigeria and developed stock market using directed acyclic graph with Bayesian estimation techniques for the period of March 11, 2020 to July 31, 2021. The dynamic Granger causal test of both the contemporaneous and autoregressive estimation were done using the Markov Chain Monte Carlo (MCMC) simulation method with Metropolis-Hasting (MH) sampling technique. The graphical structure of the instantaneous and autoregressive results shows returns correlation for Nigeria's stock market and both China and India's stock market while absence of return correlation are found for both US and UK stock market. The result implies that Nigeria's stock market has potential diversification benefit for the US and UK investors during pandemic crises. In addition, US stock market returns is found to depend on China stock market returns while volatility spill over runs from the US stock market to China's stock market. Last, UK stock market tends to depend on India's stock market. The implication of the study is that Nigeria's stock market is integrated with China and India's stock market while China's stock market is linked to the US stock market such that any financial shock from the lead stock markets is transmitted to the lagged stock markets. [ABSTRACT FROM AUTHOR]

The rabies virus (RABV) is the exclusive lyssavirus affecting both wild and domestic mammalian hosts in the Americas, including humans. Additionally, the Americas stand out as the sole region where bat rabies occurs. While carnivore rabies is being increasingly managed across the region, bats are emerging as significant reservoirs of RABV infection for humans and domestic animals. Knowledge of the bat species maintaining rabies and comprehending cross-species transmission (CST) and host shift processes are pivotal for directing surveillance as well as ecological research involving wildlife reservoir hosts. Prior research indicates that bat RABV CST is influenced by host genetic similarity and geographic overlap, reflecting host adaptation. In this study, we compiled and analyzed a comprehensive nucleoprotein gene dataset representing bat-borne RABV diversity in Argentina and the broader Americas using Bayesian phylogenetics. We examined the association between host genus and geography, finding both factors shaping the global phylogenetic structure. Utilizing a phylogeographic approach, we inferred CST and identified key bat hosts driving transmission. Consistent with CST determinants, we observed monophyletic/paraphyletic clustering of most bat genera in the RABV phylogeny, with stronger CST evidence between host genera of the same family. We further discuss Myotis as a potential ancestral spreader of much of RABV diversity. [ABSTRACT FROM AUTHOR]

Spring viremia of carp virus (SVCV) is a rhabdovirus that primarily infects cyprinid finfishes and causes a disease notifiable to the World Organization for Animal Health. Amphibians, which are sympatric with cyprinids in freshwater ecosystems, are considered non-permissive hosts of rhabdoviruses. The potential host range expansion of SVCV in an atypical host species was evaluated by testing the susceptibility of amphibians native to the Pacific Northwest. Larval long-toed salamanders Ambystoma macrodactylum and Pacific tree frog Pseudacris regilla tadpoles were exposed to SVCV strains from genotypes Ia, Ib, Ic, or Id by either intraperitoneal injection, immersion, or cohabitation with virus-infected koi Cyprinus rubrofuscus. Cumulative mortality was 100% for salamanders injected with SVCV, 98–100% for tadpoles exposed to virus via immersion, and 0–100% for tadpoles cohabited with SVCV-infected koi. Many of the animals that died exhibited clinical signs of disease and SVCV RNA was found by in situ hybridization in tissue sections of immersion-exposed tadpoles, particularly in the cells of the gastrointestinal tract and liver. SVCV was also detected by plaque assay and RT-qPCR testing in both amphibian species regardless of the virus exposure method, and viable virus was detected up to 28 days after initial exposure. Recovery of infectious virus from naïve tadpoles cohabited with SVCV-infected koi further demonstrated that SVCV transmission can occur between classes of ectothermic vertebrates. Collectively, these results indicated that SVCV, a fish rhabdovirus, can be transmitted to and cause lethal disease in two amphibian species. Therefore, members of all five of the major vertebrate groups (mammals, birds, reptiles, fish, and amphibians) appear to be vulnerable to rhabdovirus infections. Future research studying potential spillover and spillback infections of aquatic rhabdoviruses between foreign and domestic amphibian and fish species will provide insights into the stressors driving novel interclass virus transmission events. [ABSTRACT FROM AUTHOR]

Background: Throughout the Americas, Lyssavirus rabies (RV) perpetuates as multiple variants among bat and mesocarnivore species. Interspecific RV spillover occurs on occasion, but clusters and viral host shifts are rare. The spillover and host shift of a big brown bat (Eptesicus fuscus) RV variant Ef-W1 into mesocarnivores was reported previously on several occasions during 2001–2009 in Flagstaff, Arizona, USA, and controlled through rabies vaccination of target wildlife. During autumn 2021, a new cluster of Ef-W1 RV cases infecting striped skunks (Mephitis mephitis) was detected from United States Department of Agriculture enhanced rabies surveillance in Flagstaff. The number of Ef-W1 RV spillover cases within a short timeframe suggested the potential for transmission between skunks and an emerging host shift. Materials and Methods: Whole and partial RV genomic sequencing was performed to evaluate the phylogenetic relationships of the 2021–2023 Ef-W1 cases infecting striped skunks with earlier outbreaks. Additionally, real-time reverse-transcriptase PCR (rtRT-PCR) was used to opportunistically compare viral RNA loads in brain and salivary gland tissues of naturally infected skunks. Results: Genomic RV sequencing revealed that the origin of the 2021–2023 epizootic of Ef-W1 RV was distinct from the multiple outbreaks detected from 2001–2009. Naturally infected skunks with the Ef-W1 RV showed greater viral RNA loads in the brain, but equivalent viral RNA loads in the mandibular salivary glands, compared to an opportunistic sample of skunks naturally infected with a South-Central skunk RV from northern Colorado, USA. Conclusion: Considering a high risk for onward transmission and spread of the Ef-W1 RV in Flagstaff, public outreach, enhanced rabies surveillance, and control efforts, focused on education, sample characterization, and vaccination, have been ongoing since 2021 to mitigate and prevent the spread and establishment of Ef-W1 RV in mesocarnivores. [ABSTRACT FROM AUTHOR]

Simple Summary: Chagas disease (American trypanosomiasis) poses a serious health problem in the American region, with approximately one-quarter of the Latin American population at risk of infection due to the geographical distribution of the insect vectors (Triatominae spp.). The transmission scenarios for this disease involve multiple interdependent factors. The parasite has developed, over evolutionary time, multiple strategies that have enabled its successful survival. The variables governing the transmission cycle are diverse and unique to each ecological scenario. Human intervention, such as deforestation, large-scale changes in land use, and loss of biodiversity, in the Chaco region over many years, along with sustained control interventions, may have significantly impacted the structure of wild transmission cycles and their relationships with the environment. This could potentially reduce the prevalence of the parasite in the domestic cycle. This study aims to describe the transmission dynamics of the sylvatic cycle of T. cruzi, identify factors determining potential zoonotic spillover, and explore how they could contribute to the elimination of Chagas disease as a public health problem in this area of Argentina. Trypanosoma cruzi, the causative agent of Chagas disease (American trypanosomiasis), is a highly complex zoonosis that is present throughout South America, Central America, and Mexico. The transmission of this disease is influenced by various factors, including human activities like deforestation and land use changes, which may have altered the natural transmission cycles and their connection to the environment. In this study conducted in the Argentine Chaco region, we examined the transmission dynamics of T. cruzi by collecting blood samples from wild and domestic animals, as well as triatomine bugs from human dwellings, across five sites of varying anthropic intervention. Samples were analyzed for T. cruzi infection via qPCR, and we additionally examined triatomines for bloodmeal analysis via NGS amplicon sequencing. Our analysis revealed a 15.3% infection rate among 20 wild species (n = 123) and no T. cruzi presence in 9 species of domestic animals (n = 1359) or collected triatomines via qPCR. Additionally, we found chicken (34.28%), human (21.59%), and goat (19.36%) as the predominant bloodmeal sources across all sites. These findings suggest that anthropic intervention and other variables analyzed may have directly impacted the spillover dynamics of T. cruzi's sylvatic cycle and potentially reduced its prevalence in human habitats. [ABSTRACT FROM AUTHOR]

The conservation and spatial management of marine species with limited adult mobility, such as queen conch, is dictated by larval connectivity. Effectively placed reserves provide larval spillover to harvested areas while replenishing their own population. In past studies proximate to the Exuma Cays Land and Sea Park (ECLSP), surveys and probabilistic larval transport modeling demonstrated a spillover effect from the ECLSP to surrounding fished areas, while suggesting that incoming larval sources are lacking. Previous work was expanded in both upstream and downstream directions, enabling the statistical examination of (1) how queen conch abundance was linked to predicted larval transport from breeding populations in the ECLSP and (2) how age and size changed throughout the island chain as divided by management and connectivity. Biophysical modeling predictions of larval transport from breeding within the ECLSP were significantly associated with the relative abundance of juvenile conch observed across a nearly 200‐km span. Further, the abundance and shell lip thickness (relative age) of adults and the size of juveniles were significantly larger in ECLSP than unprotected areas. This empirical support for an effective, well‐enforced marine reserve and for using biophysical larval transport modeling as a spatial planning tool should be strongly considered in conch conservation and management. [ABSTRACT FROM AUTHOR]

This retrospective study reports the isolation and characterization of Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) from a household cat in South Korea. The cat, which was presented with respiratory symptoms, was identified during a retrospective analysis of samples collected between April 2021 and March 2022. Genomic sequencing revealed that the isolated virus belonged to the Omicron variant (BA.1), coinciding with its global emergence in early 2022. This case study provides evidence for the potential of direct human-to-cat transmission of the Omicron variant in South Korea during its period of widespread circulation. Our findings underscore the importance of continuous monitoring of SARS-CoV-2 in both human and animal populations to track viral evolution and potential spillover events. [ABSTRACT FROM AUTHOR]

In order to enhance the hydrogen storage capacity of Metal-Organic Frameworks (MOFs) under moderate conditions, a high-throughput screen was used to evaluate 7622 MOFs with a Pore Limit Diameter (PLD) greater than 2.89 Å and less than 10 Å. The hydrogen adsorption capacity at 25 °C and 1 bar was calculated using grand canonical Monte Carlo (GCMC) to comprehensively evaluate the effect of pore structure characteristics on the hydrogen storage capacity of MOFs. The optimal composite mass ratio between carbon-based materials, transition metals, and MOFs was determined by Density Functional Theory (DFT). The mechanism of hydrogen spillover affecting the hydrogen storage capacity of MOFs was analyzed by preparation, characterization, and hydrogen adsorption capacity testing. To further enhance the hydrogen storage capacity of MOFs composites and improve the kinetic properties and reversibility of metal hydrides, aluminum hydride (AlH 3) was nano-confined in MOF@carbon matrix material@transition metal to form new nano-confined composites with improved dehydrogenation temperature and reduced reversibility conditions. The results showed that MOFs with a PLD in the range of 7–10 Å, porosity in the range of 0.75–0.90, and pore volume in the range of 1.4–2.2 cm3/g possess high hydrogen storage capacity. Compared to pristine MOFs, the hydrogen storage capacity of the composites with induced hydrogen spillover is at least 5 times higher. The new composites with improved kinetic hydrogen release characteristics after nano-confined AlH 3 achieve reversible hydrogen release at 150 °C and 70 bar. [Display omitted] • MOFs with PLD 7-10 Å and porosity 0.75–0.90 are suitable for hydrogen storage. • Carbon-based material@MOF@transition metal's ideal mass ratio calculated via DFT analysis. • Synergistic effect of nano-confinement and hydrogen spillover increases MOFs'H 2 storage at RT. • Nano-confinement enhances kinetic properties of AlH 3 @MOF@carbon@transition metal composites for H 2 release. [ABSTRACT FROM AUTHOR]

Background: In recent years the Asian bush mosquito Aedes japonicus has invaded Europe, including the Netherlands. This species is a known vector for a range of arboviruses, possibly including West Nile virus (WNV). As WNV emerged in the Netherlands in 2020, it is important to investigate the vectorial capacity of mosquito species present in the Netherlands to estimate the risk of future outbreaks and further spread of the virus. Therefore, this study evaluates the potential role of Ae. japonicus in WNV transmission and spillover from birds to dead-end hosts in the Netherlands. Methods: We conducted human landing collections in allotment gardens (Lelystad, the Netherlands) in June, August and September 2021 to study the diurnal and seasonal host-seeking behaviour of Ae. japonicus. Furthermore, their host preference in relation to birds using live chicken-baited traps was investigated. Vector competence of field-collected Ae. japonicus mosquitoes for two isolates of WNV at two different temperatures was determined. Based on the data generated from these studies, we developed a Susceptible-Exposed-Infectious-Recovered (SEIR) model to calculate the risk of WNV spillover from birds to humans via Ae. japonicus, under the condition that the virus is introduced and circulates in an enzootic cycle in a given area. Results: Our results show that Ae. japonicus mosquitoes are actively host seeking throughout the day, with peaks in activity in the morning and evening. Their abundance in August was higher than in June and September. For the host-preference experiment, we documented a small number of mosquitoes feeding on birds: only six blood-fed females were caught over 4 full days of sampling. Finally, our vector competence experiments with Ae. japonicus compared to its natural vector Culex pipiens showed a higher infection and transmission rate when infected with a local, Dutch, WNV isolate compared to a Greek isolate of the virus. Interestingly, we also found a small number of infected Cx. pipiens males with virus-positive leg and saliva samples. Conclusions: Combining the field and laboratory derived data, our model predicts that Ae. japonicus could act as a spillover vector for WNV and could be responsible for a high initial invasion risk of WNV when present in large numbers. [ABSTRACT FROM AUTHOR]

Pathogen spillover corresponds to the transmission of a pathogen or parasite from an original host species to a novel host species, preluding disease emergence. Understanding the interacting factors that lead to pathogen transmission in a zoonotic cycle could help identify novel hosts of pathogens and the patterns that lead to disease emergence. We hypothesize that ecological and biogeographic factors drive host encounters, infection susceptibility, and cross‐species spillover transmission. Using a rodent–ectoparasite system in the Neotropics, with shared ectoparasite associations as a proxy for ecological interaction between rodent species, we assessed relationships between rodents using geographic range, phylogenetic relatedness, and ectoparasite associations to determine the roles of generalist and specialist hosts in the transmission cycle of hantavirus. A total of 50 rodent species were ranked on their centrality in a network model based on ectoparasites sharing. Geographic proximity and phylogenetic relatedness were predictors for rodents to share ectoparasite species and were associated with shorter network path distance between rodents through shared ectoparasites. The rodent–ectoparasite network model successfully predicted independent data of seven known hantavirus hosts. The model predicted five novel rodent species as potential, unrecognized hantavirus hosts in South America. Findings suggest that ectoparasite data, geographic range, and phylogenetic relatedness of wildlife species could help predict novel hosts susceptible to infection and possible transmission of zoonotic pathogens. Hantavirus is a high‐consequence zoonotic pathogen with documented animal‐to‐animal, animal‐to‐human, and human‐to‐human transmission. Predictions of new rodent hosts can guide active epidemiological surveillance in specific areas and wildlife species to mitigate hantavirus spillover transmission risk from rodents to humans. This study supports the idea that ectoparasite relationships among rodents are a proxy of host species interactions and can inform transmission cycles of diverse pathogens circulating in wildlife disease systems, including wildlife viruses with epidemic potential, such as hantavirus. [ABSTRACT FROM AUTHOR]

Purpose: This study evaluated the effect of an increase in the time interval between hepatic intra-arterial injection of 99mTc-macroaggregated albumin (MAA) and hepatic artery perfusion scintigraphy (HAPS) on the lung shunt fraction (LSF) and perfused volume (PV) calculations in the treatment planning of selective internal radiation therapy (SIRT). Methods: The authors enrolled 51 HAPS sessions from 40 patients diagnosed with primary or metastatic liver malignancy. All patients underwent scan at the first and fourth hour after hepatic arterial injection of 99mTc-MAA. Based on single-photon emission computed tomography images, LSF values were measured from each patient's first and fourth hour images. PV1 and PV4 were also calculated based on three-dimensional images using 5% and 10% cutoff threshold values and compared with each other. Results: The authors found that the median of LSF4 was statistically significantly higher than LSF1 (3.05 vs. 4.14, p ≤ 0.01). There was no statistically significant difference between PV1 and PV4 on the 10% (p = 0.72) thresholds. Conclusions: LSF values can be overestimated in case of delayed HAPS, potentially leading to treatment cancellation due to incorrectly high results in patients who could benefit from SIRT. Threshold-based PV values do not significantly change over time; nevertheless, keeping the short interval time would be safer. [ABSTRACT FROM AUTHOR]

There is growing interest in the relationship between digitalization and environmental, social, and governance (ESG) performance, but existing research focuses on the one-way relationship and ignores the two-way mechanism. Based on a sample of 3335 listed companies in China in 2020, this study adopts a spatial simultaneous equation model to investigate the bidirectional mechanism between companies' digitalization and ESG performance. The results show that digitalization and ESG performance have a significant positive two-way mechanism; digitalization enhances ESG performance, while ESG performance promotes digitalization. The results also indicate a significant positive intra-industry spillover effect for both digitization and ESG performance. Further research shows that the relationship between digitization and ESG performance does not differ depending on the definition of spatial weights, however, the spillover effects do differ depending on the definition of spatial weights. [ABSTRACT FROM AUTHOR]

Pathogen spillover corresponds to the transmission of a pathogen or parasite from an original host species to a novel host species, preluding disease emergence. Understanding the interacting factors that lead to pathogen transmission in a zoonotic cycle could help identify novel hosts of pathogens and the patterns that lead to disease emergence. We hypothesize that ecological and biogeographic factors drive host encounters, infection susceptibility, and cross‐species spillover transmission. Using a rodent–ectoparasite system in the Neotropics, with shared ectoparasite associations as a proxy for ecological interaction between rodent species, we assessed relationships between rodents using geographic range, phylogenetic relatedness, and ectoparasite associations to determine the roles of generalist and specialist hosts in the transmission cycle of hantavirus. A total of 50 rodent species were ranked on their centrality in a network model based on ectoparasites sharing. Geographic proximity and phylogenetic relatedness were predictors for rodents to share ectoparasite species and were associated with shorter network path distance between rodents through shared ectoparasites. The rodent–ectoparasite network model successfully predicted independent data of seven known hantavirus hosts. The model predicted five novel rodent species as potential, unrecognized hantavirus hosts in South America. Findings suggest that ectoparasite data, geographic range, and phylogenetic relatedness of wildlife species could help predict novel hosts susceptible to infection and possible transmission of zoonotic pathogens. Hantavirus is a high‐consequence zoonotic pathogen with documented animal‐to‐animal, animal‐to‐human, and human‐to‐human transmission. Predictions of new rodent hosts can guide active epidemiological surveillance in specific areas and wildlife species to mitigate hantavirus spillover transmission risk from rodents to humans. This study supports the idea that ectoparasite relationships among rodents are a proxy of host species interactions and can inform transmission cycles of diverse pathogens circulating in wildlife disease systems, including wildlife viruses with epidemic potential, such as hantavirus. [ABSTRACT FROM AUTHOR]

Research has revealed a rise in family relationship problems during the COVID-19 pandemic, especially among couples with young children. However, longitudinal studies spanning the prepandemic and pandemic periods are rare. In this study, we examined changes in couple functioning during these periods. Moreover, we investigated the mediation and moderation effects of couple functioning on the association between COVID-19 stressors and harsh parenting. A total of 545 mothers (mean age 38 years, range 23–48 years) completed questionnaires on couple functioning during the prepandemic (2016–2020) and early pandemic (May–June 2020) periods. During the early pandemic, they also reported exposure to COVID-19 stressors and engaging in harsh parenting (e.g., conflicts and maltreatment). We found no overall deterioration in couple functioning during the early pandemic. Furthermore, COVID-19 stressors did not explain variance in couple functioning changes or correlate with harsh parenting. However, as hypothesized, couple functioning moderated the effect of COVID-19 stressors on harsh parenting. Only for couples with low prepandemic functioning was exposure to COVID-19 stressors associated with harsh parenting. In conclusion, our findings provided no evidence of COVID-19's detrimental effects on couples during the early pandemic. Instead, well-functioning couple relationships appear to mitigate the impact of pandemic stressors on parenting. [ABSTRACT FROM AUTHOR]

Sustainable reductions in African malaria transmission require innovative tools for mosquito control. One proposal involves the use of low-threshold gene drive in Anopheles vector species, where a ‘causal pathway’ would be initiated by (i) the release of a gene drive system in target mosquito vector species, leading to (ii) its transmission to subsequent generations, (iii) its increase in frequency and spread in target mosquito populations, (iv) its simultaneous propagation of a linked genetic trait aimed at reducing vectorial capacity for Plasmodium, and (v) reduced vectorial capacity for parasites in target mosquito populations as the gene drive system reaches fixation in target mosquito populations, causing (vi) decreased malaria incidence and prevalence. Here the scope, objectives, trial design elements, and approaches to monitoring for initial field releases of such gene dive systems are considered, informed by the successful implementation of field trials of biological control agents, as well as other vector control tools, including insecticides, Wolbachia, larvicides, and attractive-toxic sugar bait systems. Specific research questions to be addressed in initial gene drive field trials are identified, and adaptive trial design is explored as a potentially constructive and flexible approach to facilitate testing of the causal pathway. A fundamental question for decision-makers for the first field trials will be whether there should be a selective focus on earlier points of the pathway, such as genetic efficacy via measurement of the increase in frequency and spread of the gene drive system in target populations, or on wider interrogation of the entire pathway including entomological and epidemiological efficacy. How and when epidemiological efficacy will eventually be assessed will be an essential consideration before decisions on any field trial protocols are finalized and implemented, regardless of whether initial field trials focus exclusively on the measurement of genetic efficacy, or on broader aspects of the causal pathway. Statistical and modelling tools are currently under active development and will inform such decisions on initial trial design, locations, and endpoints. Collectively, the considerations here advance the realization of developer ambitions for the first field trials of low-threshold gene drive for malaria vector control within the next 5 years. [ABSTRACT FROM AUTHOR]

While diverse strains of low-pathogenicity avian influenza have circulated in wild birds for a long period of time, there has previously been little pathology in wild birds, ducks have been the primary and largely asymptomatic wild reservoir, and spillover into mammals has been limited and rare. In recent years, a high-pathogenicity avian influenza (HPAI) virus has emerged on the global scene and shifted the previously established dogmas for influenza infection. High-pathogenicity avian influenza has expanded into wildlife in unprecedented numbers and species diversity, with unmatched disease severity for influenza in wildlife. As the disease ecology of influenza has shifted with this new variant, significant efforts are underway to understand disease course, pathology, and species susceptibility. Here we focus primarily on the impact that HPAl has had in wild mammals while framing these novel spillovers within the context of significantly expanding disease in avian species and geography. The clinical and pathology presentations of HPAl in these atypical hosts are discussed, as well as prognosis and risk for continued spillover. The companion Currents in One Health by Runstadler and Puryear, AJVR, May 2024, provides further context on viral reservoirs and possible routes of direct or environmental transmission and risk assessment of viral variants that are emerging within wildlife. [ABSTRACT FROM AUTHOR]

The emergence of infectious diseases with pandemic potential is a major public health threat worldwide. The World Health Organization reports that about 60% of emerging infectious diseases are zoonoses, originating from spillover events. Although the mechanisms behind spillover events remain unclear, mathematical modeling offers a way to understand the intricate interactions among pathogens, wildlife, humans, and their shared environment. Aiming at gaining insights into the dynamics of spillover events and the outcome of an eventual disease outbreak in a population, we propose a continuous time stochastic modeling framework. This framework links the dynamics of animal reservoirs and human hosts to simulate cross-species disease transmission. We conduct a thorough analysis of the model followed by numerical experiments that explore various spillover scenarios. The results suggest that although most epidemic outbreaks caused by novel zoonotic pathogens do not persist in the human population, the rising number of spillover events can avoid long-lasting extinction and lead to unexpected large outbreaks. Hence, global efforts to reduce the impacts of emerging diseases should not only address post-emergence outbreak control but also need to prevent pandemics before they are established. [ABSTRACT FROM AUTHOR]