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A non-local theory is proposed to model dense granular flows. The idea is to describe the rearrangements occurring when a granular material is sheared as a self-activated process. A rearrangement at one position is triggered by the stress fluctuations induced by rearrangements elsewhere in the material. Within this framework, the constitutive law, which gives the relation between the shear rate and the stress distribution, is written as an integral over the entire flow. Taking into account the finite time of local rearrangements, the model is applicable from the quasi-static regime up to the inertial regime. We have checked the prediction of the model in two different configurations, namely granular flows down inclined planes and plane shear under gravity, and we show that many of the experimental observations are predicted within the self-activated model. [ABSTRACT FROM AUTHOR]