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In this paper, we report the structural characteristics of Ti0.5Fe2.5O4/CS nanocomposite, synthesized through the coprecipitation method. Analysis of the formed nanocomposite particles' structure was successfully carried out by means of X-ray diffraction, and the functional groups were identified by means of Fourier-transform infrared spectroscopy. The morphology and average particle size were successfully observed and determined through scanning electron microscopy. The diffraction peaks confirmed the presence of Ti0.5Fe2O4 in the spinel structure, while the infrared spectrum analysis provided the functional groups of both elements with metal-oxygen bond identified at a wavenumber of 642.3 cm−1 and chitosan-typical functional groups such as amide I stretching vibration. The data analysis of scanning electron microscopy image exhibited an average particle size of 18.2 nm with agglomeration. [ABSTRACT FROM AUTHOR]

In this paper, we report the fabrication and characterization of silica/Fe2.18Zn0.82O4 nanocomposites used as doxorubicin anti-cancer drug carrier. Silica/Fe2.18Zn0.82O4 nanocomposites were synthesized by using coprecipitation method followed by tetraethyl-orthosilicate hydrolysis process. The synthesis products were characterized by means of XRD, XRF, FTIR, UV Vis, and SEM. XRD characterization resulted in particle size of 7.14 nm. The presence of Si and Zn in the samples was confirmed from XRF characterization result: 49.2% for Si and 14.1% for Zn. Furthermore, functional groups of FTIR results also detected Si-O-Si bond in the wavelength of 1023 and 1091 cm-1. Based on the analysis of drug loading, silica/Fe2.18Zn0.82O4 nanocomposites had exemplary absorbance for doxorubicin as an anti-cancer drug. The release profile of the drug also showed the possibility of its use in medical application since release kinetic indicated stable drug dose in a relatively long period. [ABSTRACT FROM AUTHOR]

Drug delivery agent based on magnetite/hydroxyapatite/chitosan nanocomposite (nMHAC) has been successfully manufactured using natural materials. The synthesis of nMHAC was carried out using the coprecipitation method, consisting of three stages, namely magnetite synthesis, hydroxyapatite solution preparation, and nMHAC synthesis. The obtained diffraction pattern indicates the formulation of nMHAC forming the magnetite and HA phase; each has cubic and hexagonal crystal structures, which are nanostructured. The FTIR spectrum also shows the presence of absorbance bands from the Fe-O group, hydroxyl, phosphates, and amides, which are the characteristic of nMHAC. The obtained nMHAC particles are in the spherical shape distributed in the nanometric scale, with an average size of 27.8 nm. The doxorubicin loading efficiency of the nMHAC is 83.9%, positioning nMHAC as a candidate in drug delivery application. [ABSTRACT FROM AUTHOR]

In this study, we report green synthesis of Fe3O4 nanoparticles based on biosurfactant Saccharum officinarum extract using sonochemical method. The phase purity of the sample was characterized using an X-ray diffractometer (XRD). Based on the XRD characterization, the addition of biosurfactant S. officinarum did not alter the inverse spinel cubic of Fe3O4 nanoparticles. Quantitatively, the crystallite size was calculated using the Debye-Scherrer equation, resulted crystallite size of 11 nm. The functional groups of the Fe3O4 nanoparticles based on the biosurfactant S. officinarum were also investigated through Fourier-transform infrared (FTIR) characterization. Based on the FTIR data analysis, the presence of Fe3O4 was indicated by the presence of Fe-O bonds at 573 cm-1. Other bonds such as O-H that showed the presence of intramolecular hydrogen bonds from cellulose and S. officinarum were also found at wavenumbers of 3280-3533 cm−1. Furthermore, the presence of the surfactant S. officinarum extract was also found at a wavenumber of 1054 cm−1. It represented the presence of C-O-C bonds from the glycosidic ether band. Therefore, it can be inferred that the utilization of biosurfactant S. officinarum extract has been successfully carried out in the synthesis of Fe3O4 nanoparticles. [ABSTRACT FROM AUTHOR]

Natural surfactant-based iron oxides from Zingiber officinale extract have been successfully synthesized through the coprecipitation method. Black iron oxide-Zingiber officinale has been characterized by using an X-ray Diffractometer. The diffraction data from black iron oxide and black iron oxide-Zingiber officinale show a comparable pattern with the highest peak was at 35.7° angle and field of hkl (311). According to a calculation using the Debye-Scherrer equation, the particle size obtained from black iron oxide and black iron oxide-Zingiber officinale was 2.7 nm and 2.5 nm, respectively. The addition of Zingiber officinale extracts as the natural surfactant declined the particle size of iron oxide nanoparticles. Thus, it indicates that the abundant amount of hydroxyl within the Zingiber officinale extract effectively protects black iron oxide's surface from aggregation. Besides, the extract of gingerol full Zingiber officinale that coats the black iron oxide nanoparticle also contributed to obstructing the particle agglomeration. [ABSTRACT FROM AUTHOR]

Fe3O4 and α-Fe2O3 are potential magnetic materials to be developed in medical fields, especially for antibacterial agents. In order to support their application performance, Fe3O4 and α-Fe2O3 were combined with ZnO nanoparticles via an organic assisted route. The characterizations of Fe3O4/α-Fe2O3/ZnO nanocomposites were done employing FTIR, XRD, and SEM to study their functional groups, crystal structure, morphology, and particle distribution. The data analysis for infrared spectra presented that some peaks detected the presence of Fe3O4, α-Fe2O3, and ZnO at some positions. The phase composition for the Fe3O4, α-Fe2O3, and ZnO was respectively of 90.50%, 5.0%, and 4.5%. The SEM images showed that the Fe3O4/α-Fe2O3/ZnO nanocomposite tended to be constructed in spherical and plate shapes with the particle sizes of 12.25 ± 2.5 nm and 27.5 ± 2.5 nm, respectively. Furthermore, the antibacterial test presented that the Fe3O4/α-Fe2O3/ZnO nanocomposite had reasonable inhibition rate for S. aureus, B. Subtilis, and E coli. [ABSTRACT FROM AUTHOR]