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Summary: With the end of Moore's law, new paradigms are investigated for more scalable computing systems. One of the promising directions is to examine the data representation toward higher data density per hardware element. Multiple valued logic (MVL) emerged as a promising system due to its advantages over binary data representation. MVL offers higher information processing within the same number of digits when compared with binary systems. Accessing memory is considered one of the most power‐ and time‐consuming instructions within a microprocessor. In the quest for building an entire ternary computer architecture, we propose investigating the potential opportunities of ternary address decoders. This paper presents three different designs for ternary address decoder based on CNTFET. The first design is based on a cascade of Ternary to Binary blocks (T2B) and a binary decoder. The second design is built using the hierarchical structure and enables signals. The third is designed utilising a pre‐decoder and ternary logic gates. A comparison of the proposed designs and the binary address decoder in terms of power and delay under different supply voltage and temperature values is introduced. Simulation results show that the second design has the least power and delay of the proposed ternary designs. [ABSTRACT FROM AUTHOR]

Background: Nipah belongs to the genus Henipavirus and the Paramyxoviridae family. It is an endemic most commonly found at South Asia and has first emerged in Malaysia in 1998. Bats are found to be the main reservoir for this virus, causing disease in both humans and animals. The last outbreak has occurred in May 2018 in Kerala. It is characterized by high pathogenicity and fatality rates which varies from 40% to 70% depending on the severity of the disease and on the availability of adequate healthcare facilities. Currently, there are no antiviral drugs available for NiV disease and the treatment is just supportive. Clinical presentations for this virus range from asymptomatic infection to fatal encephalitis.Objective: This study is aimed at predicting an effective epitope-based vaccine against glycoprotein G of Nipah henipavirus, using immunoinformatics approaches.Methods and Materials: Glycoprotein G of the Nipah virus sequence was retrieved from NCBI. Different prediction tools were used to analyze the epitopes, namely, BepiPred-2.0: Sequential B Cell Epitope Predictor for B cell and T cell MHC classes II and I. Then, the proposed peptides were docked using Autodock 4.0 software program. Results and Conclusions. The two peptides TVYHCSAVY and FLIDRINWI have showed a very strong binding affinity to MHC class I and MHC class II alleles. Furthermore, considering the conservancy, the affinity, and the population coverage, the peptide FLIDRINWIT is highly suitable to be utilized to formulate a new vaccine against glycoprotein G of Nipah henipavirus. An in vivo study for the proposed peptides is also highly recommended. [ABSTRACT FROM AUTHOR]