1. Suzuki−Miyaura Coupling of NHC−Boranes: A New Addition to the C−C Coupling Toolbox.
- Author
-
Julien Monot, Malika Makhlouf Brahmi, Shau-Hua Ueng, Carine Robert, Marine Desage-El Murr, Dennis P. Curran, Max Malacria, Louis Fensterbank, and Emmanuel Lacôte
- Subjects
- *
CARBENES , *HETEROCYCLIC compounds , *BORANES , *ADDITION reactions , *CHEMICAL bonds , *CHLORIDES , *COMPLEX compounds - Abstract
Complexes of triaryl- and trialkylboranes with N-heterocyclic carbenes (NHCs) participate in Suzuki−Miyaura cross-coupling reactions and provide coupled products in good yields under base-free conditions. The reaction can be applied to Csp2−Csp2and Csp2−Csp3carbon−carbon bond formation with triflates, iodides, bromides, and chlorides. These results enrich the utility of NHC−borane complexes, which can be added to the toolkit of Suzuki−Miyaura cross-couplings, along with boronic acids and organotrifluoroborates. [ABSTRACT FROM AUTHOR]
- Published
- 2009
- Full Text
- View/download PDF