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A retail business is basically the business opportunity for retailers in Pakistan, it is said that when analysis is done on buyer's requirements, that what changed the attitude and purchasing power of market in Pakistan. The competitive market has involved all segments of market in it for increasing interest of retailer to do more. Our local market activities on the basis of retail requires more effort to competitive market and variation in the market. If anybody survives its existence in the competition of businesses for acceleration in the traditional views business and business factors are based on the decision making of individuals that improved value of research. The local market opted the judgement on questionnaire but a question order to identify analysis of business and performance of market in Pakistan but the capital services, labor services and marketing services towards successful efforts for improvement of local market business. The outcome of the current analysis proved that the pattern of ethics having direct relationship with decision-making of management for local activities when data for 2017 to 2022 is analyzed, depending on marketing perspective which is more dominant and influential in Pakistan by taking facts from Lahore and Faisalabad. To understand the human nature of Business ethics and management decision, it is very important to note that the important elements of achieving retail business is showing different results for this study. [ABSTRACT FROM AUTHOR]

A descriptive study was conducted in the Department of Respiratory Medicine in a tertiary care center of Ambala. Aim of the study was to determine the prevalence of fungal infection among patient presents with sputum negative old treated pulmonary tuberculosis. The study was carried out among 39 post treated cases of Pulmonary Tuberculosis, whose sputum or bronchial wash showed isolation of Aspergillus. Demographic details and clinical findings were noted. Data collected were entered into Excel spreadsheet and quantitative data were expressed as number and percentage. The presentation of pulmonary aspergillosis in treated cases of pulmonary TB varies from aspergilloma (51.3%) to chronic necrotizing pulmonary aspergillosis (38.4%) to allergic bronchopulmonary aspergillosis (10.3%). Hemoptysis (79.5%) of varying severity was the most common symptom. Most of the patients were farmers by occupation. The most common species were Aspergillus fumigatus; others were Aspergillus flavus, Aspergillus niger and Aspergillus terrus in 23.2%, 20.5%, and 12.8%, respectively. Here we conclude that Aspergillus fumigatus was the most frequently isolated species in our region and aspergilloma was the commonest pulmonary manifestation as post-TB sequel. [ABSTRACT FROM AUTHOR]

Objective: Identification of allergens by intradermal test in patients with asthma, allergic rhinitis, and eczema. Materials and Methods: Intradermal test was performed in 100 patients of Ambala over an 8-year period to identify the common allergens. A total of 197 allergens including 50 types of pollen, 19 fungi, 17 insects, 14 types of dust, 6 animal dander, 7 types of fabric and feather and 82 types of foods, dust mite, and parthenium were tested. Results: In this study, the major allergens were pollen (51%) followed by foods (28.9%), insects (26.9%), fungus (12.6%), dusts (6.7%). Among pollen allergens, Brassica campestris (8%) was a major allergen followed by Ageratum conyzoides (7%) and Artemisia scoparia (6%) Cannabis sativa, Cynodon dactylon and Maerua arenaria (5%). Among the fungal group, Alternaria tenuis, Aspergillus flavus, Aspergillus fumigates, Candida albicans, Penicillium sp., Rhizopus nigricans (3%), Fusarium solani (2%) were found. In the insect group, mosquito (7%), ant (6%), grasshopper (5%), locust (male), moth, and house fly (4%) were the major allergens. Among the dust allergens, grain dust rice (3%), straw dust, house dust, and grain dust bajra (2%) were found. Among the food allergens, prawn (5%), almonds, Baker's yeast, Bengal gram (3%) and mushroom, mango ripe, rajma, cinnamon, chocolate, beans fresh, and areca nut (2%) were found. Conclusion: It can be said that the knowledge may help to create a mapping of allergens in this area and help to treat patients by immunotherapy or avoidance strategy. [ABSTRACT FROM AUTHOR]

Introduction: the association of Tuberculosis and Diabetes Mellitus is a cause of concern for the health sector. The coexistence of these two highly prevalent diseases has made the already existing treatments very complex. This issue is of particular significance to developing countries like India that bear a significant burden of these two diseases. Methods: retrospective analysis of 1000 consecutively admitted patients in a tertiary care hospital were analyzed for the coexistence of Tuberculosis and Diabetes Mellitus. Results: the study found that a significant proportion of diabetic patients had coexistent tuberculosis (65.5%). Rural population was predominantly affected in both the genders. The study observed that the coexistence of these two conditions increased with advanced age. Conclusion: the coexistence of Diabetes Mellitus with Tuberculosis needs to identified early and adequately addressed. The rural population needs to be educated about these two conditions and seek timely medical care. [ABSTRACT FROM AUTHOR]

Purpose The purpose of this paper is to study the integration between fused deposition modeling (FDM) technology and abrasive flow machining process to improve the surface quality of FDM printed parts. FDM process has some limitations in terms of accuracy and surface finish. Hence, post-processing operations are essential to increase the quality of the part.Design/methodology/approach Initially, a sustainable polymer abrasive gel-based media (SPAGM) using natural polymer and natural additives (waste vegetable oil) was prepared using different combinations of (abrasive mesh size, percentage of abrasives and percentage of liquid synthesizer); then the characterization of media was done to check various properties. As media is an essential part in the process which helps in increase the surface finish, it needs to have some desired characteristics such as the following: the developed SPAG needs to hold the abrasives; its viscosity has to be medium so that it can easily flow through the machine; and its thermal stability caused by the increase in the temperature during various cycles of operation. For that, it is characterized rheologically as well as thermally to find its various properties.Findings Experiments were performed on FDM-printed parts using an L9 orthogonal array with different parameters to find their effect on the workpiece. Scanning electron microscope images of SGAPM showed sharp edges of abrasive particles and bonding pattern between polymer chain molecules. Good surface finish and material removal rate (MRR) was observed at high pressure and long finishing time with 50 per cent abrasive concentration.Originality/value The authors confirm that this work is original and has neither been published elsewhere nor is it currently under consideration for publication elsewhere. [ABSTRACT FROM AUTHOR]

The interaction of genetic and environmental factors can determine individual susceptibility to various cancers. We studied the influence of NAT2 and codon 72 p53 polymorphisms on 151 patients with lung cancer and an equal number of matched population controls. Polymorphisms of NAT2 and p53 were determined by PCR-RFLP techniques. The results were analyzed using logistic regression analysis. A statistically significant relationship between NAT2*5 and NAT2*6 alleles and lung cancer risk was observed. In addition, the population with slow acetylator alleles for NAT2*5 and NAT2*6 had a significantly higher risk of lung cancer compared with rapid acetylator alleles both in smokers and nonsmokers. The combined genotype of heterozygous arginine ( Arg)/proline ( Pro), Pro/Pro, and slow acetylator alleles of NAT2*5 and NAT2*6 showed higher, although not significant, risk of lung cancer compared with Arg/Arg and rapid acetylator alleles of NAT2*5 and NAT2*6. In conclusion, these findings suggest that the influence of NAT2 genotype, alone or in combination with p53 genotype, may confer increased susceptibility to lung cancer. [ABSTRACT FROM AUTHOR]

DNA ligases play an essential role in repair, replication, and recombination of DNA, and catalyzes the formation of a phosphodiester bond at a nick junction on single- and double-strand breaks. We have conducted a hospital-based case–control study to examine the role of polymorphism of DNA repair gene ligase I ( LIGI) in the context of lung cancer risk for north Indian population. One hundred, fifty-one primary lung cancer cases and an equal number of matching hospital controls were collected. The LIGI polymorphism was determined by using the PCR-RFLP method. The association between polymorphisms in the LIGI gene with the risk of lung cancer was estimated by computing odds ratios (ORs) and a 95% confidence interval (CI) using a Multivariate Logistic Regression Analysis. The risk for lung cancer was not associated for individuals featuring LIGI (AC) (OR –0.8, 95% CI = 0.44–1.40) and (AA) (OR –0.8, 95% CI = 0.41–1.80) genotypes. The DNA repair gene ( LIGI) may not be playing an important role in modulating the risk of lung cancer in the north Indian population. [ABSTRACT FROM AUTHOR]