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Introduction: Prior to transplantation of segmental liver grafts to adult recipients, it is crucial to confirm that the graft size is safe for the donor, yet adequate for the recipient''s metabolic needs. Computed tomography (CT) and magnetic resonance imaging (MRI) are the current best standards. We applied a new formula to estimate right liver lobe weight in living donors and compared our results with CT and MRI.Methods: Between August 1998 and December 20, 91 adults received right lobes from living donors. Donor liver volumes were assessed by CT or MRI. Actual weights of right lobe grafts were determined after back table flushing. We estimated whole liver weights using the formula: 772 × body surface area (BSA). Right lobe liver weight was calculated as 57% of the estimated whole liver weight (R-57).Results: Mean actual right lobe weight (n = 90) was 855.83 ± 183.4 g. Estimated right lobe weight was 858.08 ± 90.80 (R-57, P = NS); 1077.35 ± 263.07 mL for CT (P = .0001), and 1185.07 ± 350.10 mL for MRI (P = .0001). Mean graft–recipient weight ratio (GRWR) was 1.23%; there was no significant difference with R-57 GRWR but there was a difference from CT and MRI-GRWR (P = .001). The proportion of cases of estimated right lobe weight and GRWR within 20% of the corresponding actual value were 80% and 90%, respectively, for R-57 versus 36% and 43% for the imaging studies (P = .0001).Conclusion: With readily available software to calculate BSA, physicians can predict right lobe weight knowing only the donor''s height and weight. CT and MRI will only be necessary for anatomic liver mapping. [Copyright &y& Elsevier]