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5 results on '"Kapche, Gilbert D.W.F."'

1. Prenylated arylbenzofuran derivatives from Morus mesozygia with antioxidant activity

Author

Kapche, Gilbert D.W.F., Fozing, Christian. D., Donfack, Jean H., Fotso, Ghislain W., Amadou, Dawe, Tchana, Angèle. N., Bezabih, Merhatibeb, Moundipa, Paul F., Ngadjui, Bonaventure T., and Abegaz, Berhanu M.

Subjects
*BENZOFURAN, *PLANT extracts, *SEPARATION (Technology), *MULBERRY, *ANTIOXIDANTS, *CHEMICAL structure, *SPECTRUM analysis
Abstract

Abstract: Five prenylated arylbenzofurans, moracins Q–U, were isolated from Morus mesozygia (Moraceae). Their structures were elucidated on the basis of spectroscopic evidence. Along with these compounds, 3β-acetoxyurs-12-en-11-one, marsformoxide, moracin C, moracin M, moracin K, artocarpesin, cycloartocarpesin, morachalcone A were also isolated. Four of the five compounds, (moracins R–U) displayed potent antioxidant activity. [Copyright &y& Elsevier]

Published
2009
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3. Sonhafouonic acid, a new cytotoxic and antifungal hopene-triterpenoid from Zehneria scabra camerunensis

Author

Kongue, Michel D.T., Talontsi, Ferdinand M., Lamshöft, Marc, Kenla, Timothee J.N., Dittrich, Birger, Kapche, Gilbert D.W.F., and Spiteller, Michael

Subjects
*ALTERNATIVE medicine, *BIOLOGICAL models, *CRUSTACEA, *MASS spectrometry, *MEDICINAL plants, *MUTAGENS, *NUCLEAR magnetic resonance spectroscopy, *PLANT diseases, *TERPENES, *PLANT extracts, *DESCRIPTIVE statistics
Abstract

Abstract: A new hopene-type triterpenoid, namely sonhafouonic acid 1a was isolated from Zehneria scabra camerunensis, together with eight known compounds. The structure of 1a was established by extensive NMR and high resolution MS techniques and confirmed by single-crystal X-ray crystallographic analysis. Compound 1a exhibited inhibitory activity against mycelial growth of two peronosporomycete phytopathogens Pythium ultimum and Aphanomyces cochliodes and cytotoxicity towards brine shrimp larvae (Artemia salina) at 10μg/mL. [Copyright &y& Elsevier]

Published
2013
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5. New stilbene dimers against amyloid fibril formation

Author

Rivière, Céline, Papastamoulis, Yorgos, Fortin, Pierre-Yves, Delchier, Nicolas, Andriamanarivo, Soahary, Waffo-Teguo, Pierre, Kapche, Gilbert D.W.F., Amira-Guebalia, H., Delaunay, Jean-Claude, Mérillon, Jean-Michel, Richard, Tristan, and Monti, Jean-Pierre

Subjects
*STILBENE, *DIMERS, *AMYLOID beta-protein, *ALZHEIMER'S disease treatment, *OLIGOMERS, *RESVERATROL, *DRUG derivatives, *CLUSTERING of particles, *NATURAL products
Abstract

Abstract: Twenty stilbene derivatives and moracin M extracted from natural products were tested against amyloid-β peptide (Aβ) aggregation. Results of stilbene monomer derivatives indicated that interaction with resveratrol and piceid was specific. Concerning oligomers, scirpusin A and ε-viniferin glucoside demonstrated a strong inhibition of the aggregation process. [Copyright &y& Elsevier]

Published
2010
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