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The authors discuss the proper time to use intravenous paracetamol in neonates. The authors say that intravenous paracetamol can be used to treat neonates' mild to moderate pain if enteral paracetamol is not feasible because of clinical circumstance, such as immediate postoperative care. Moreover, they do not advocate intravenous paracetamol use in preterm neonates with less than 32 weeks postconceptional age (PCA) before pharmacodynamic or pharmacokinetic studies are conducted in neonates.

The article reports that computer programs and calculations used to determine drug doses can be incorrect. A case study of a three-month old infant in the intensive care unit is presented. Using a Microsoft Excel program and body weight to calculate doses of noradrenaline, the patient was mistakenly given a dose seven times higher than necessary for two hours. To prevent this problem from continuing, a paediatric resuscitation chart has been introduced for use in drug infusions. Efforts to reduce software and information technology related accidents are presented.