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ABSTRACT Planning is one of the most critical areas within Project Management, with adequate task scheduling and resource management being of vital importance, especially at the project's outset. This paper introduces an Artificial Intelligence designed for the automatic planning of photovoltaic plant (PV) construction projects, encompassing various tasks such as engineering, procurement, logistics, construction and commissioning, and including the substation and transmission line, scheduling a total of 100 tasks, which constitute a basic Engineering, Procurement and Construction project planning. The model is trained using a total of 50 real‐case project plans for PVs. The results demonstrate that the model successfully and effectively carries out photovoltaic project planning, marking a significant step towards digital transformation. [ABSTRACT FROM AUTHOR]

This article is the third essay in a series on the historical development of psychological configuration of the self and presents the development of the first types of proto-individualistic psychological configuration that emerged in markedly gregarious contexts from the earliest times of human development, which represent the first examples of psychological configuration of the individualistic self archetype. The first and most elementary types of protoindividualistic configuration that emerged in archaic times are explored, showing the four oldest types of proto-individualism of which there is evidence. The most varied types of proto-individualism that emerged in the post-Neolithic and early civilizations are also explored and discussed, representing transformations or variations of archaic types and other new types of configuration that emerge in the already very diverse contexts of social organization. The main characteristics of the configurations presented are discussed within the framework of the dynamic evolution of the two general archetypes of psychological configuration. [ABSTRACT FROM AUTHOR]

Purpose: This paper seeks to establish an Industry 4.0 maturity model for manufacturing SMEs. This research presents the characteristics of the proposed model, which takes the elements and the scope of the fourth industrial revolution, as well as the dimensions and assessment scales of some maturity models already applied. Likewise, this document shows the modeling process and the model's validation in SMEs in the city of Bogotá-Colombia. Design/methodology/approach: To determine the criteria of the maturity model, 6 major stages have been established: Literature Review, Development of the model; Validation of the model; Application of the model; Data analysis; and Conclusion and Recommendations. Findings: Considering the validation of some maturity models shown in the literature review, and aligned with the purpose of this article, 8 dimensions have been established to measure the maturity level of SMEs: Service; Operations; Quality; Products; Documented information-Big Data; Leadership and strategy; Communication; and Culture and people. A model has been generated that allows evaluating the degree of compliance in each dimension for manufacturing SMEs. The model can be applied to companies in any industry. Also, it can determine the degree of implementation compliance of companies in the same sector. Research limitations/implications: According to the literature reviewed, SMEs, especially those in Latin America, still do not have a culture of applying the elements of Industry 4.0. Therefore, in the research, it was not easy to understand the intrinsic variables of Industry 4.0 that SMEs have applied in different areas, which does not allow us to have the current context of SMEs and from that perspective to have a better simulation of the business model maturity. Practical implications: The model presented in this document serves as a basis for SMEs in Latin America to establish a baseline measurement in relation to the application of Industry 4.0 elements in companies. Social implications: What is intended with this work is to frame a baseline so that companies can understand their current maturity level in terms that industry 4.0 could cover. Likewise, they can generate actions for the appropriation of new technologies that allow them to be more competitive. This document can be taken and applied by those entrepreneurs companies who wish to measure their operations. Originality/value: The essential point for the generation of the maturity level measurement model is focused on determining the necessary dimensions on which the evaluation is based. In the literature found, most models focus their dimensions on measuring the digital in their processes and tangentially evaluate the organizational structure and the relationship between them. Additionally, the authors who address the organization as a whole do not reveal the details for SMEs to self-evaluate. The models found have only been implemented to evaluate one company alone or individually. This model presents the core dimensions holistically and explicitly, taking important criteria such as quality, service, communication, and the culture of all employees. Additionally, it shows in detail the model that allows SMEs of the manufacturing sector to self-assess themselves in each dimension and in turn the degree of the business sector in which they are or belong. [ABSTRACT FROM AUTHOR]

IL-15 has emerged as a potentially relevant target in the IL-17 response in psoriasis. However, its mechanism is poorly characterized in humans. IL-15 and IL-23 are constitutively expressed in the psoriatic lesion. Also, IL-15 is considered a susceptibilityassociated gene in psoriasis, as are IL-23R, and HLACW6. Here, we studied the effect of IL-15 and IL-23 stimulation on the cytokine response of CLA+/CLA- T cells from 9 psoriasis patients and 3 healthy control subjects. To this end, CLA + and CLA- T cells from blood samples were cultured with epidermal cells from skin biopsies and treated with IL-15 and IL-23. After five days of culture, cytokines in supernatant were measured by ELISA or fluorescent bead-based immunoassay. There was a statistically significant increase in IL-17F and IL-17A production (P < .001) in cocultures of psoriasis skin-homing CLA + T cells with epidermal cells when stimulated with IL-15 and IL-23, but this effect was not observed in the cells of healthy controls. Interestingly, this response was reduced by around 50 to 80% by blocking HLA class I and II molecules. Our results point to the synergic action of IL-15 and IL-23 selectively for CLA + cells in psoriasis, leading to the induction of Th17 cell-related cytokines. [ABSTRACT FROM AUTHOR]

Assess the sustainability of electricity provision for rural families through off-grid Photovoltaic Systems (PVS) in Bolivia during the last 10 years, is the essential core of this research. The sustainability analysis is considered under a multidimensional approach: documental analysis complemented by a field research and semi-structured interviews with local experts. In the Bolivian case more than 36 thousand PVS have been installed in the last 10 years under different schemes, but more than 90% of these, are out of operation, shown the absence of sustainability approach in these interventions. For this and considering the international experience, is sketched a proposal under an integrality approach. The proposal contemplates substantial modifications in the way of granting the SFV to the families, their faculties as well as the institutional roles; a tariffed service has been suggested as it happens throughout an off-network system. [ABSTRACT FROM AUTHOR]

Ocean acidification is a growing problem that affects global environment. Its effects are detectable now, putting the most extensive water resource on the planet at risk and influencing the climate changes that can be documented across the globe. This paper analyzes the protection of the sea as a measure to ensure a healthy environment for future generations, guaranteeing a better way of life for them. We present the different principles governing bioethics, and we establish their relationship with the processes of sustainable development and the increase of acidification in the ocean, which affects a large number of communities of scarce resources in the world. [ABSTRACT FROM AUTHOR]

The study explores the generational contrast between personal values in students and nurses and their adjustment to the predictions of the theory of changing values. The sample was comprised of 369 students and nurses who were divided into three groups: students (n = 150), nurses under age 40 (n = 114), and nurses between 41 and 60 years of age (n = 105). The participants reported their values on an open questionnaire, in order of priority. The reports were organized into value categories to analyze the differences between groups. Two trends were found in the report on personal values: in some cases, they fit what is predicted by the theory of changing values; in others, they contradict it. The importance of these findings and the need to empower training oriented towards the values of the nursing profession is discussed. The study contributes to what we know about the change in personal values among nursing professionals. [ABSTRACT FROM AUTHOR]

Hypertension is a major health problem, and noncompliance with treatment has been identified as the predominant reason for failure of hypertension therapy. Although it is generally assumed to be a silent disease, many hypertensive patients develop false beliefs concerning specific symptoms they use to estimate if their blood pressure (BP) is high. These false beliefs should be modified in order to improve control of the disease. The study presents a feedback procedure applied in a sample of 60 hypertensive patients expressing beliefs in false symptoms associated with their BP. After application of the procedure, 88% of the patients modified or eliminated their beliefs in false symptoms, and we found significant differences (p <.05) in the reports of adherence to pharmacological treatment before and after receiving the feedback procedure, as well as a significant improvement in the reports of difficulties with the other treatment elements (diet, exercise, control of emotions). The therapeutic possibilities of an easy procedure to apply within the healthcare setting is discussed. [ABSTRACT FROM AUTHOR]

The present study evaluates the personal values reported by a sample of New York Hispanic residents using an open evaluation format in which the participants identified and prioritized their personal values. Four hundred and forty-five participants were assigned to one of three groups: Young (n= 159), Adult (n= 168) and Senior (n= 118). The values reported were categorized into post-materialist, materialist or non-classifiable. The Percentage Difference Index between post-materialist and materialist values was calculated in order to determine the value profile for each age group. The results showed that reports of personal values and values attributed to the participants' own generation were similar in Adult and Senior groups, but were very different in the Young Group, with a differential report of post-materialist values. Furthermore, exposure to American culture did not appear to have a significant effect on the reported values of NYC Hispanics. To confirm these findings, we need to conduct additional studies with larger samples of culturally diverse populations. [ABSTRACT FROM AUTHOR]

The purpose of this article is to analyze the evolution of the International Journal of Psychology & Psychological Therapy (IJP&PT) throughout its first decade of publication (from years 2001 to 2010), comparing the quality measures that result from applying the three most important social science databases: Thomson-Reuters Web of Science, Elsevier-Scopus, and Google Scholar. We compared the three databases, using the citations recorded for IJP&PT as a "case study" applied to a journal. As quality indicators we used IJP&PT data available in the three databases, as well as other indicators related to the internationality of the journal. The results shows a increasing tend in all quality criteria during the time period evaluated as a first-level journal among psychology journals edited in Spain. Also, the results shows serious discrepancies when the data of the three databases are compared. We discuss the need to improve the criteria used by the databases, as well as the convenience to use several quality indicators for journals' evaluation. [ABSTRACT FROM AUTHOR]

The present study has as main goal the exploration of risk behaviors in a sample of 85 university undergraduate students from the Universidad del Salvador, Buenos Aires, Argentina. All participants responded to a anonymous questionnaire with items related to health habits in food, sleep, exercise, substance use, and beliefs about health status. The results indicated that incoming students differ in their risk profiles from the students of last course. In addition, 42% of the students of last course reports not to have received information about health in university. A high percentage of students report positive beliefs on his/her health status regardless to the report of several risk behaviors. We discuss if the university education context need to pay more attention to health education. [ABSTRACT FROM AUTHOR]

Social change and personal change. A preliminary study of the intergenerational change of values. The present study evaluates the personal values that inform a sample of participants in a open format of response that permit the participants identifying and prioritizing their top ten life values. In addition, participants were asked to report of the principal values of the majority of persons of his/her same age and of the people of different ages. The sample was made up of 449 participants (40,3% men, 59,7% women) that were distributed in three groups of young people (N= 196), adult people (N= 154), and senior people (N= 99). The results indicate, principally, that the reports of personal values and generational values are very similar in case of adult and senior people, and very different in the case of young people, with the presence of negative and postmaterialistic values. The results are discussed in the frame of the theory on intergenerational change of values. [ABSTRACT FROM AUTHOR]

The study of health beliefs shows that it is during the adolescent period that takes place the formation of these important repertoires that will determine in part the behaviors related to health along life. The present study explore several health and disease beliefs in a sample of 70 type I diabetic teenagers (8-15 years old). Results confirm that adolescence is a relevant moment in the formation of health and illness beliefs and some differences between beliefs showed for diabetic teenagers. [ABSTRACT FROM AUTHOR]

Despite the availability of effective therapy, hypertension remains poorly controlled and noncompliance has been identified as the predominant reason for failure of hypertension therapy. The aim of this study is to explore, (a) the patient's reports about their adherence and difficulties for the fulfillment of the treatment; (b) the relationship between information they had received about the consequences for health of hypertension and what they really believed about; (c) the patients' beliefs about the hypertension as a disease; and (d) the change in their way of living after the diagnosis. 171 hypertensive patients participated. Results shows that only 11,7% of patients reported not having problems to follow treatment, identifying as the main difficulties the adherence to diet and exercise; a high percentage of patients showed no correspondence between their beliefs about the consequences of hypertension and the information received in medical consultation; only 57% of the patients reported to have the idea of hypertension as a chronic disease; and 40,9% of the patients reported only some changes in their way of life after being diagnosed which might indicate failures in adherence at the beginning of the treatment. The importance of these results to improve adherence to treatment in hypertensive patients is discussed. [ABSTRACT FROM AUTHOR]

This paper presents an analysis of the mobility of the university students in Psychology Degree in the university Spanish system. The study shows that the mobility of the students of Psychology is scanty, similar to the mobility in most of careers. In the academic year 2003/04 only 15,6% of the students of psychology was registered in universities located in provinces different to the familiar residence. The study analyzes the preferences showed by the students who move to study psychology and the universities with major capacity of students' captation. Discussion concerned the expectations of dishminising mobility as consecuenque of actual changes in height education politics. [ABSTRACT FROM AUTHOR]

Data available on health habits and health beliefs in Spanish medical population is scarce. The objective of this study was to explore some health habits (i.e., tobacco and alcohol consume) as well as the knowledge and beliefs regarding those habits among physicians and medical students. The sample was 147 participants from various hospitals in Spain. A questionnaire specifically designed for this study was used to obtain data about the target variables. Results show that 47,6% of participants are smokers, and 71,7% inform to be alcohol consumers. A positive relation between age and frequency of consumption was found in both habits. Participants demonstrate to have an adequate level of knowledge and beliefs in relation to the risks for health that the use of tobacco and alcohol entails, contrasting clearly with their consumption patterns. The health habits of this sample do not differ from those founded in the general population, even though participants show a correct level of knowledge and beliefs on these habits, thus emphasizing the lack of correspondence between health knowledge, beliefs and health habits. [ABSTRACT FROM AUTHOR]

Peptides obtained from whey proteins have been associated with different biological properties, but most peptides are usually degraded during the digestive process. In this work, hydrolysates were prepared from a whey protein concentrate obtained by ultrafiltration of Colombian traditional cheese whey and subsequent enzymatic hydrolysis using alcalase, chymotrypsin and flavourzyme. The antioxidant and angiotensin-converting enzyme (ACE) inhibitory properties were evaluated, and peptide profile was determined by ultra-high pressure liquid chromatography tandem mass spectrometry (UHPLC-MS/MS). Changes in the above biological properties and peptide profile after simulated gastrointestinal digestion were then investigated. Before enzymatic hydrolysis, the alcalase hydrolysate showed higher 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging capacity, whereas an inhibition greater than 85% of ACE activity was observed for the alcalase and chymotrypsin hydrolysates. In both tests, the flavourzyme hydrolysates showed lower activities. Different changes in the above biological activities were observed after gastrointestinal digestion of the alcalase and chymotrypsin hydrolysates: ABTS radical scavenging ability increased, whereas ACE inhibitory capacity decreased significantly. The alcalase hydrolysate obtained from ultrafiltrated whey protein concentrate showed high antioxidant and ACE inhibition capacities and higher survivability of peptides after in vitro gastrointestinal digestion. • Bioactivity of Columbian cheese whey hydrolysates was tested. • Whey hydrolysates were subjected to INFOGEST in vitro digestion. • In vitro digestion affected bioactivity and peptide profile. [ABSTRACT FROM AUTHOR]

Candida albicans (CA) infections have been associated with psoriasis onset or disease flares. However, the integrated immune response against this fungus is still poorly characterized in psoriasis. We studied specific immunoglobulins in plasma and the CA response in cocultures of circulating memory CD45RA− cutaneous lymphocyte antigen (CLA)+/− T cell with autologous epidermal cells from plaque and guttate psoriasis patients (cohort 1, n = 52), and also healthy individuals (n = 17). A complete proteomic profile was also evaluated in plaque psoriasis patients (cohort 2, n = 114) regarding their anti-CA IgA levels. Increased anti-CA IgA and IgG levels are present in the plasma from plaque but not guttate psoriasis compared to healthy controls. CA cellular response is confined to CLA+ T cells and is primarily Th17. The levels of anti-CA IgA are directly associated with CLA+ Th17 response in plaque psoriasis. Proteomic analysis revealed distinct profiles in psoriasis patients with high anti-CA IgA. C-C motif chemokine ligand 18, chitinase-3-like protein 1 and azurocidin were significantly elevated in the plasma from plaque psoriasis patients with high anti-CA levels and severe disease. Our results indicate a mechanism by which Candida albicans exposure can trigger a clinically relevant IL-17 response in psoriasis. Assessing anti-CA IgA levels may be useful in order to evaluate chronic psoriasis patients. [ABSTRACT FROM AUTHOR]

Harmful algal blooms (HABs) are episodes of high concentrations of algae that are potentially toxic for human consumption. Mollusc farming can be affected by HABs because, as filter feeders, they can accumulate high concentrations of marine biotoxins in their tissues. To avoid the risk to human consumption, harvesting is prohibited when toxicity is detected. At present, the closure of production areas is based on expert knowledge and the existence of a predictive model would help when conditions are complex and sampling is not possible. Although the concentration of toxin in meat is the method most commonly used by experts in the control of shellfish production areas, it is rarely used as a target by automatic prediction models. This is largely due to the irregularity of the data due to the established sampling programs. As an alternative, the activity status of production areas has been proposed as a target variable based on whether mollusc meat has a toxicity level below or above the legal limit. This new option is the most similar to the actual functioning of the control of shellfish production areas. For this purpose, we have made a comparison between hybrid machine learning models like Neural-Network-Adding Bootstrap (BAGNET) and Discriminative Nearest Neighbor Classification (SVM-KNN) when estimating the state of production areas. The study has been carried out in several estuaries with different levels of complexity in the episodes of algal blooms to demonstrate the generalization capacity of the models in bloom detection. As a result, we could observe that, with an average recall value of 93.41% and without dropping below 90% in any of the estuaries, BAGNET outperforms the other models both in terms of results and robustness. • Presence of toxicity in molluscan shellfish meat as a target for predicting HABs. • Hybrid AI methods outperform classical methods in predicting HABs. • Analyzing the behavior of hybrid machine learning models against unbalanced datasets. • BAGNET offers the best results in the prediction of HABs in complex regions. [ABSTRACT FROM AUTHOR]

In the Th2 high group, in contrast to the Th2 low, the IL-13 response by SEB CLA SP + sp T cells directly correlated with EASI score and plasma levels of CCL17 and sIL-2R (Figure 2A-C). I Staphylococcus aureus i , memory skin-homing cutaneous lymphocyte-associated antigen (CLA) SP + sp T cells and IL-13 constitute relevant players in atopic dermatitis (AD) pathogenesis.1 Since circulating CLA SP + sp T cells reflect cutaneous abnormalities present in human inflammatory skin diseases,2 an I ex vivo i coculture model made of purified circulating CLA SP +/- sp effector and central memory T cells and autologous lesional epidermal cells was established. SEB-induced IL-13 production in CLA+ memory T cells defines Th2 high and Th2 low responders in atopic dermatitis. [Extracted from the article]

Objectives: To show that digital informed consent (DIC) improves the subjective understanding of information and, therefore, informed consent. Patients and Methods: A nonblinded randomized controlled trial was performed in 84 patients who had undergone transurethral resection of bladder, transurethral resection of prostate, or ureterorenoscopy between July 2017 and March 2018. The DIC group watched a hyperrealistic simulation on a tablet device before surgery. After surgery and again 30 days later, both groups completed a validated questionnaire that measured subjective understanding, anxiety, and utility of and need for information. Results: The mean ± SD age of the participants was 68.7 ± 11.1 years. Nine of 84 patients (10.7%) did not complete the questionnaire. A total of 42 patients were allocated to the DIC group and 42 to the control group. The mean ± SD score for immediate subjective understanding in the DIC group was 14.5% higher than in the control group (72% ± 17.5% vs 57.5% ± 23.5%, respectively; P = 0.006). There was no statistical difference in anxiety, utility of and need for information relative to delayed subjective understanding. In subgroup analysis, subjective understanding scores were higher, but not significantly so, among patients with low and higher education levels in the DIC group than in the control group (68% ± 18.1% vs 54% ± 22.5% [P = 0.06] and 76% ± 18.3% vs and 66% ± 21.9%, respectively [P = 0.89]). Conclusion: Hyperrealistic simulations improved subjective understanding of information and, therefore, informed consent for endourological procedures. [ABSTRACT FROM AUTHOR]

This article reports a structural equation model (SEM) with four latent variables to measure the relationship between information and communication technologies (ICT) integration with supply chain flexibility, supply chain agility, and company's performance. The SEM integrates six hypotheses with relationships among variables and is validated with 378 responses from manufacturing sector to a questionnaire and partial least squares technique is used to evaluate it and test the hypotheses statistically. A sensitivity analysis is conducted in different scenarios to know conditional probabilities of occurrence of dependent variables, since a scenario has occurred in the independent variable with low and high success level. Findings indicate that ICT integration in supply chain facilitate to monitoring the production process, partners integration and have a direct effect on agility and flexibility for manufacturers, providing an active material' or subassemblies' flow among partners with greater visibility and making agile and joint decision-making. [ABSTRACT FROM AUTHOR]

This study explores the reporting of personal values in a sample of German participants through means of a questionnaire using open questions. The sample consisted of a total of 255 participants (60% female and 40% male) with an age range of between 18 and 100 years old. The participants indicated their personal values openly and in order of priority. The results showed that participants primarily considered personal values to be those related to basic life concerns (e.g. family, friendship, health) and to social relations (e.g. honesty, reliability, empathy). A significant trend was found among middle-age participants (31-60 years old) to report values of a political-social nature, whilst older generations (61+ years old) tended to give less importance to values related to social relations. The results were discussed making reference to the socio-cultural change related to post-modernism and were compared and contrasted with the results of major value surveys obtained in sociological studies. [ABSTRACT FROM AUTHOR]

Aims: To investigate differences and similarities in college students’ drinking motives in Spain and in Hungary. Methods: A total of 550 Spanish (mean age 22.7, SD = 3.2) and 997 Hungarian (mean age 22.4, SD = 2.7) college students completed the Drinking Motive Questionnaire Revised Short Form (DMQ-R SF) and answered other alcohol-related questions. Data were analyzed by confirmatory factor analysis, t-test and structural equation modeling. Results: The DMQ-R SF demonstrated good psychometric properties in both countries. The rank order of the motives (social > enhancement > coping > conformity) was identical in the two countries. However, Hungarian students scored higher on enhancement, social and coping motives than Spanish students. In both the Hungarian and the Spanish population, enhancement motives were associated with drinking frequency and drunkenness, while coping motives were associated with alcohol-related problems. Among Spanish students, a significant relationship was found between alcohol-related problems and enhancement motives as well. Conclusion: Despite the substantial differences in the drinking culture of both countries, drinking motives showed overwhelming similarities (e.g. rank order of motives and the particular relationships between motives and alcohol outcomes). Only few differences (e.g. Hungarian college students indicated a higher level of motives) were found in cross-national comparison. Our results imply that programs targeting risky drinking motives are likely to be successfully adapted to different drinking cultures in Europe. [ABSTRACT FROM AUTHOR]

Objective. To study the evolution of 64 patients initially diagnosed with ASAP (atypical small acinar proliferation). Material and methods. Between 1998 and the end of 2003, 64 patients were diagnosed at our centre with ASAP. Results. The mean age of the patients assessed was 69 years (SD 6.4 years), the median prostate-specific antigen (PSA) level was 7.1 ng/ml (range 2–39 ng/ml) and 25% of the patients had a suspicious rectal examination. These 64 patients were subjected to re-biopsy. At re-biopsy, we diagnosed 27 patients (42%) with prostate adenocarcinoma. We classified patients into two groups depending on whether they did ( n =27) or did not ( n =37) have tumours. There were no significant differences in median PSA level between the two groups. The rectal examination was suspicious in 14% of patients without tumours and in 39% with tumours. Radical prostatectomy was applied to 20/28 patients (71%) diagnosed with prostate cancer. In these 20 patients, the median tumour volume was 0.4 cm 3 (range 0.1–3.2 cm 3 ) and 44% of the tumours were significant. The 37 patients with an unsuspicious histology were subjected to follow-up for a median of 12 months (range 1–30 months). The median PSA level in these patients was 5.7 ng/ml (range 0.8–28 ng/ml). A third biopsy was performed in three of these patients in view of an elevated PSA level, and one result was positive. Conclusions. In our experience, a pathological result of ASAP is associated with a definitive diagnosis of prostate cancer in 42% of cases. Moreover, a significant cancer was found in 44% of patients subjected to radical prostatectomy. We therefore systematically perform repeat biopsies on all patients with a histological result of ASAP. [ABSTRACT FROM AUTHOR]