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Being one of the conditions presenting with patellar pain, Hoffa's syndrome is characterized with inflammation of the fat tissue in the patellar region. In advanced stage, this may lead to transformation of the fibrocartilage tissue and ossification of the infrapatellar fat pad. Some cases can be associated with tumors or tumor-like conditions. In this article, we describe a 72-year-old female case suffering from knee pain for a long time and discuss the end-stage Hoffa's disease and function of the infrapatellar fat pad in the light of literature. [ABSTRACT FROM AUTHOR]

A 37-year-old male patient, who is an athletic runner, developed anterior knee pain of acute onset after prolonged running and swelling of his right knee. The patient experiences more pain when he flexes the knee and a sense of catching together with grade 1 effusion. The patient was clinically suspected to have internal derangement and MRI study of his right knee was ordered to exclude such possible diagnosis. The MRI study revealed the following: a hypointense lesion in the infrapatellar pad of fat in T2-weighted images (WI), postcontrast T1 WI with fat saturation demonstrated no enhancement, and STIR sequence showed slightly hyperintense lesion with minimal knee effusion. The MRI findings supported the diagnosis of Hoffa's syndrome, and arthroscopic resection of the fat pad was performed. There was a significant improvement in the symptoms and function after the surgery. [ABSTRACT FROM AUTHOR]