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AbstractThis study compared the weed suppression ability of a native cover crop species phacelia (Phacelia tanacetifolia), an introduced cover crop species rye (Secale cereale L.), and a no cover crop (herbicide‑managed) system in a vineyard. Cover crops were sown in the interrow spaces of the grapevine rows. Percent weed cover after the cover crop termination was lower in the interrow of the phacelia than the no cover crop plots. During the cover crop growing season, phacelia suppressed weeds more than rye. However, the weed seedbank of the cover crop plots was greater than that of the no cover crop plots. [ABSTRACT FROM AUTHOR]

The Asian elephant Elephas maximus is at risk of extinction as a result of anthropogenic pressures, and remaining populations are often small and fragmented remnants, occupying a fraction of the species' former range. Once widely distributed across China, only a maximum of 245 elephants are estimated to survive across seven small populations. We assessed the Asian elephant population in Nangunhe National Nature Reserve in Lincang Prefecture, China, using camera traps during May–July 2017, to estimate the population size and structure of this genetically important population. Although detection probability was low (0.31), we estimated a total population size of c. 20 individuals, and an effective density of 0.39 elephants per km2. Social structure indicated a strong sex ratio bias towards females, with only one adult male detected within the population. Most of the elephants associated as one herd but three adult females remained separate from the herd throughout the trapping period. These results highlight the fragility of remnant elephant populations such as Nangunhe and we suggest options such as a managed metapopulation approach for their continued survival in China and more widely. [ABSTRACT FROM AUTHOR]

We examined the effect of a labile soil amendment, compost, and recalcitrant biochar on soil microbial community structure, diversity, and activity during turfgrass establishment. Two application rates of biochar (B1 at 12.5 t ha-1and B2 at 25 t ha-1), a 5 centimeter (cm) green waste compost treatment (CM) in top soil, a treatment with 12.5 t ha-1 biochar and 5 cm compost (B1+CM), and an unamended control (CK) treatment were prepared and seeded with tall fescue. Overall, results of phospholipid fatty acid analysis (PLFA) profiling and Illumina high-throughput sequencing of 16S rRNA genes amplified from soil DNA revealed significant shifts in microbial community structures in the compost amended soils whereas in biochar amended soils communities were more similar to the control, unamended soil. Similarly, increases in enzymatic rates (6–56%) and nitrogen-induced respiration (94%) were all largest in compost amended soils, with biochar amended soils exhibiting similar patterns to the control soils. Both biochar and compost amendments impacted microbial community structures and functions, but compost amendment, whether applied alone or co-applied with biochar, exhibited the strongest shifts in the microbial community metrics examined. Our results suggest application of compost to soils in need of microbiome change (reclamation projects) or biochar when the microbiome is functioning and long-term goals such as carbon sequestration are more desirable. [ABSTRACT FROM AUTHOR]

Sleep health is a multidimensional construct that includes adequate duration, quality, and appropriately timed sleep that may be influenced by environmental factors. In this review, we focus on how an individual's living and sleeping environment, both the surrounding neighborhood physical and social features and the atmosphere around them, may impact their sleep health. We explore the associations of the physical environment (urban density, recreational facilities, green space, mixed land use, and healthy food stores), neighborhood deprivation (disadvantage and disorder), and the social environment (social cohesion, safety, and stigma) with sleep in both adult and pediatric populations. We investigate how physical and social environmental features may lead to alterations in the timing, duration, and quality of sleep and contribute to the most prevalent sleep disorders: insomnia, sleep apnea, and circadian rhythm disorders. We also review how ambient factors such as artificial light, environmental noise, and air pollution may contribute to sleep pathology. We have included key studies and recent emerging data regarding how the differential distribution of environmental factors that may affect sleep health may contribute to sleep health disparities. [ABSTRACT FROM AUTHOR]

The concept of sleep health provides a positive holistic framing of multiple sleep characteristics, including sleep duration, continuity, timing, alertness, and satisfaction. Sleep health promotion is an underrecognized public health opportunity with implications for a wide range of critical health outcomes, including cardiovascular disease, obesity, mental health, and neurodegenerative disease. Using a socioecological framework, we describe interacting domains of individual, social, and contextual influences on sleep health. To the extent that these determinants of sleep health are modifiable, sleep and public health researchers may benefit from taking a multilevel approach for addressing disparities in sleep health. For example, in addition to providing individual-level sleep behavioral recommendations, health promotion interventions need to occur at multiple contextual levels (e.g., family, schools, workplaces, media, and policy). Because sleep health, a key indicator of overall health, is unevenly distributed across the population, we consider improving sleep health a necessary step toward achieving health equity. [ABSTRACT FROM AUTHOR]

Functional diversity is increasingly recognized by microbial ecologists as the essential link between biodiversity patterns and ecosystem functioning, determining the trophic relationships and interactions between microorganisms, their participation in biogeochemical cycles, and their responses to environmental changes. Consequently, its definition and quantification have practical and theoretical implications. In this opinion paper, we present a synthesis on the concept of microbial functional diversity from its definition to its application. Initially, we revisit to the original definition of functional diversity, highlighting two fundamental aspects, the ecological unit under study and the functional traits used to characterize it. Then, we discuss how the particularities of the microbial world disallow the direct application of the concepts and tools developed for macroorganisms. Next, we provide a synthesis of the literature on the types of ecological units and functional traits available in microbial functional ecology. We also provide a list of more than 400 traits covering a wide array of environmentally relevant functions. Lastly, we provide examples of the use of functional diversity in microbial systems based on the different units and traits discussed herein. It is our hope that this paper will stimulate discussions and help the growing field of microbial functional ecology to realize a potential that thus far has only been attained in macrobial ecology. [ABSTRACT FROM AUTHOR]

Social jetlag, a misalignment between sleep timing on the weekend and during the work week, is associated with depressive symptoms among adults across both sexes. A previous study found that later sleep timing was associated with depressive symptoms in women but not men. To date, however, no research has investigated whether the association between social jetlag and depression varies by sex among adolescents. The current study assessed self-reported sleep, depressive symptoms, and demographic information from 3058 adolescents (48% female, mean [SD] age 15.59 [0.77] years) from the age 15 wave of the Fragile Families and Child Wellbeing Study (FFCWS). Social jetlag was calculated as the absolute value of the midpoint of sleep on the weekend minus the midpoint of sleep during the school week. Depressive symptoms were measured through a modified 5-item version of the Center for Epidemiologic Studies Depression Scale (CES-D). We assessed whether the associations among sleep duration on school nights, social jetlag, and depressive symptoms were similar between male and female adolescents using multiple linear regression. In fully adjusted models, sex moderated the association between school night total sleep time and depressive symptoms (p < 0.001) and between social jetlag and depressive symptoms (p = 0.037). In females, but not in males, school night total sleep time was negatively associated with depressive symptoms (p < 0.001), whereas social jetlag (p < 0.001) was positively and independently associated with depressive symptoms. The results indicate the importance of regular sleep timing across the week and adequate sleep duration for the maintenance of optimal emotional health among female adolescents. [ABSTRACT FROM AUTHOR]

Rigid work schedules are negatively associated with adults' sleep. Less is known about whether parents' work schedule flexibility influences their children's sleep. We examined associations of mothers' perceived work schedule flexibility with their children's sleep over time and whether these associations were mediated by bedtime routine adherence. Two-waves of data were drawn from the Fragile Families and Child Wellbeing Study, a sample of socioeconomically disadvantaged households in large US cities (N = 1040). When the focal children were ages 5 and 9, mothers reported their work schedule flexibility and their child's bedtime adherence, sleep duration, and difficulty getting to sleep. Cross-sectionally, higher levels of maternal perceived work schedule flexibility were associated with longer child sleep duration and a lower likelihood of having difficulty getting to sleep; these associations were mediated by greater child bedtime adherence. Longitudinally, increases in mothers' perceived work schedule flexibility from child ages 5 to 9 predicted increases in child bedtime adherence at age 9, which, in turn, predicted increases in child sleep duration at age 9. Increases in perceived work schedule flexibility also predicted a decreased likelihood of children having difficulty getting to sleep, but this association was not mediated by changes in child bedtime adherence. These results suggest that mothers' perceived work schedule flexibility may be a social determinant of child sleep health, largely through influencing bedtime adherence. Future interventions could consider how to improve bedtime practices in families with working mothers, including by increasing work schedule flexibility perceived by working parents to promote child sleep health. [ABSTRACT FROM AUTHOR]

Phosphorus ore extraction for soil fertilization supports the demand of modern agriculture, but extractable resource limitations, due to scarcity, impose a P reuse and recycling research agenda. Here we propose to integrate biochar production (pyrogenic carbon) with municipal and agricultural waste management systems, to recover and reuse phosphorous that would otherwise be lost from the ecological food web. A meta-analysis and available data on total P in biochar indicated that P-enriched feedstocks include animal manure, human excreta, and plant-biomass collected from P-polluted sites. Phosphorus in biochar could participate in P equilibriums in soils and is expected to supply P. The release, sorption and desorption of P by biochar will codetermine the potential of P replenishment by biochar and P loss from biochar-amended soils. Abiotic and biotic factors are expected to affect sorption/desorption of P between biochar and soil aggregates, and P acquisition by plants. Chemical extraction, using acid or alkaline solutions, is considered as a means for P retrieval from high P biochar, especially for biochar with high heavy metal contents. To bridge the gap between academia and practice, this paper proposes future development for phosphorus acclamation by pyrolysis: 1) identification of high-P bio-waste for pyrolysis; 2) retrieval of P by using biochar as soil amendment or by chemical leaching; 3) biochar modification by inorganic nutrients, P solubilizing microorganisms and other organic matter; and 4) compatible pyrolysis equipment fit to the current waste management context, such as households, and waste water treatment plants. [ABSTRACT FROM AUTHOR]

Given the pervasive use of screen-based media and the high prevalence of insufficient sleep among American youth and teenagers, this brief report summarizes the literature on electronic media and sleep and provides research recommendations. Recent systematic reviews of the literature reveal that the vast majority of studies find an adverse association between screen-based media consumption and sleep health, primarily via delayed bedtimes and reduced total sleep duration. The underlying mechanisms of these associations likely include the following: (1) time displacement (ie, time spent on screens replaces time spent sleeping and other activities); (2) psychological stimulation based on media content; and (3) the effects of light emitted from devices on circadian timing, sleep physiology, and alertness. Much of our current understanding of these processes, however, is limited by cross-sectional, observational, and self-reported data. Further experimental and observational research is needed to elucidate how the digital revolution is altering sleep and circadian rhythms across development (infancy to adulthood) as pathways to poor health, learning, and safety outcomes (eg, obesity, depression, risk-taking). [ABSTRACT FROM AUTHOR]

Although numerous studies among adults have shown a U-shaped association between sleep duration and health outcomes, fewer studies have investigated the theory that children also have an optimal sleep duration range, with both lower and upper limits. We evaluated whether children’s sleep duration at ages 5 and 9 has a U-shaped association with both behavioral problems and physical health at age 9. We analyzed data from 1,965 participants in a longitudinal birth cohort, the Fragile Families and Child Wellbeing Study. This sample of children was 52% male and approximately 22% non-Hispanic White, 52% non-Hispanic Black, 23% Hispanic, and 3% some other race/ethnicity. The child’s primary caregiver reported the predictor of interest: sleep duration at age 5 and age 9. Both children and primary caregivers reported on outcomes of the child’s behavior problems (internalizing and externalizing) and overall physical health. We found that the association between children’s sleep duration and well-being was typically nonlinear and U-shaped. Adjusting for their sleep duration at age 5, children who sleep either too much or too little at age 9 had higher levels of behavior problems and scored lower on a global measure of physical health. These nonlinear patterns were similar whether children or primary caregivers reported child outcomes, with the exception that there was a linear and increasing association of longer sleep duration and caregiver-rated child health. This study highlights that both short and long sleep duration may be risk factors for adverse behavioral and health outcomes in school-age children. [ABSTRACT FROM AUTHOR]

Biochar can function as an effective low-cost inoculum carrier for plant growth-promoting bacteria. Here, we examined the shelf life and inoculum potential of Pseudomonas putida UW4 (UW4) and the potential for further optimization by adding nutrient supplements to a pinewood biochar (PBC) that was used as an inoculum carrier. PBC-600 was produced by pyrolysis at 600 °C and modified with Luria-Bertani broth, a worm casting extract, or mixed with earthworm castings. All treatments were compared with peat as a standard reference material. Subsequent experiments examined survival and root colonization potential of UW4. Results showed that the addition of LB broth to PBC-600 increased the growth of UW4 in storage, but that both supplemented and non-supplemented biochar were similarly effective for establishing a high population density of UW4 in the rhizosphere of inoculated plants. The population density represented by16S ribosomal RNA (rRNA) gene copy numbers for UW4 was correlated with above ground plant biomass ( r = 0.6725), which had a positive effect on alleviating salinity stress for the host plant. Analysis of community compositions in the rhizosphere by high throughput sequencing and Kohonen self-organizing maps indicated that high population abundances of UW4 were positively correlated with the abundance of Arthrobacter, Sphingomonas, Rubellimicrobium, and Gematimonas, but were negatively correlated with other dominant taxa. The results suggest that organic nutrient supplementation of the carrier does not promote increased shelf life or inoculum efficacy, but suggests the need for further studies on how biochar and inoculants can be used to shape plant-associated microbial communities. [ABSTRACT FROM AUTHOR]

Studies on the molecular ecology of microbial communities in soils amended with biochar are potentially biased by changes in soil DNA extraction efficiency caused by DNA adsorption to biochar. To examine the extent to which this might occur, we evaluated a kit-free method for soil DNA extraction as well as MoBio's PowerSoil® commercial kit with and without phenol/chloroform/isoamyl (PCI) modification. DNA extraction efficiencies were quantified for soils amended with four biochar types that were added to either clay or sand soils at a rate of 3 % ( w/ w). Prior to extraction, all soil treatments were spiked with bacteria transformed with plasmids carrying a green fluorescent protein ( gfp) gene, as a molecular marker. DNA purity and yield were assessed spectrophotometrically and fluorometrically. Quantitative PCR (qPCR) was utilized to enumerate gfp copy numbers extracted per gram soil. Results showed that qPCR-quality DNA could be efficiently extracted from biochar-amended soils using the PowerSoil® kit with or without PCI modification. However, the modified protocol resulted in an average of approximately 3 times greater yield than the provided protocol. Of the tested methods, none demonstrated reduced DNA extraction efficiency or purity when amended with the varying biochars. [ABSTRACT FROM AUTHOR]

Biochar materials have greatly variable physical and chemical properties, which will affect their abilities to serve as carriers for introducing bacteria into soils. Here we examined biochars made from 5 feedstocks produced at 2 highest treatment temperatures (HTT's) by slow pyrolysis. Peat and vermiculite, which are traditional inoculum carriers, and liquid inoculum with no carrier, were included for comparison. All of the carriers were inoculated with a liquid suspension of the plant growth promoting rhizobacterial (PGPR) strain, Enterobacter cloacae UW5, carrying a green fluorescent protein (GFP) marker. Inoculum survival was determined using quantitative PCR to enumerate the GFP markers in DNA extracted from non-sterilized soils directly after incorporation of the inoculated carriers and after a 4-week incubation. The biochars were characterized with respect to carbon and nitrogen content, specific surface area, pH, electrical conductivity, water holding capacity, pore opening diameters, and hydrophobicity to identify specific attributes that influence the survival of the inoculant after introduction into soil. The results indicated that chemical properties of biochar, particularly nitrogen and pH, were among the most important characteristics affecting initial inoculum survival and hence likely the shelf life. However, once incorporated into soil, physical features, including surface area, pore opening diameters, and water-filled pore spaces, were more closely associated with inoculum survival. All biochars tested performed as well as vermiculite and none demonstrated detrimental effects on the UW5 population. The best biochar was that made from pinewood at a HTT of 600 °C (Pine600), which performed as well as peat and sustained higher population densities than vermiculite. The Pine600 biochar was further tested to assess its effect on the expression of 1-aminocyclopropane-1-carboxylic acid (ACC) deaminase and auxin synthesis, both of which were unaffected by the presence of biochar at 2% or 5% (w/v) concentrations. [ABSTRACT FROM AUTHOR]

Long sleep duration has been associated with increased risk of cardiovascular disease ( CVD) and all-cause mortality. Inflammation and coagulation have been hypothesized as possible physiological pathways to explain this association, although specific biomarkers have not been studied. Using longitudinal data from 3942 postmenopausal women in the Women's Health Initiative observational study and clinical trials, we investigated whether fibrinogen, an acute-phase inflammatory protein involved in blood clotting, mediates the associations between sleep duration and coronary heart disease ( CHD) and mortality among women. Fibrinogen levels were associated positively with self-reported long sleep duration (9+ h per night), CHD and all-cause mortality, even after adjustment for a range of sociodemographic characteristics, cardiovascular risk factors and comorbidities.Compared with self-reported 7-8 h per night sleep duration, self-reported long sleep duration was associated with increased odds of CHD [odds ratio ( OR) = 2.05, 95% confidence interval ( CI): 1.02-4.11]. Adjustment for fibrinogen levels reduced the increased odds of CHD associated with long sleep by approximately 8 percentage points ( OR = 1.97, 95% CI: 0.98-3.97). A similar reduction in the OR was observed with mortality. For both outcomes there is support for partial mediation of 6-7%, suggesting that fibrinogen may be a mechanism through which long sleep duration is associated with CHD and mortality. [ABSTRACT FROM AUTHOR]

Background Breast cancer and its treatment introduce numerous physiologic, psychological, social, and economic stressors to a woman with the diagnosis. Allostatic load, a composite score of biomarkers representing physiologic dysregulation, may serve as a measure of the biological burden of breast cancer. This study investigates the association between breast cancer and allostatic load scores by comparing allostatic load scores in those with a history of breast cancer to those without, stratified by race. Methods Black and white women aged 35 to 85 were analyzed using the data from NHANES 1999-2008 ( n = 4875 women, of which 188 women had a history of breast cancer). Stratified by race, we ran multivariate analyses with history of breast cancer as a predictor for elevated allostatic load while adjusting for other potentially confounding variables. Results Although a history of breast cancer was not associated with elevated allostatic load in white women, it was significantly associated with elevated allostatic load in black women after adjusting for age, income, education, insurance type, smoking status, alcohol intake, and physical activity [Odds Ratio (OR) 2.08 (95%CI 1.02, 4.22)]. Furthermore, an interaction between black and having a history of breast cancer was found to be significant in predicting elevated allostatic load scores after adjusting for demographic, behavioral, and comorbidity characteristics. Conclusions These results suggest that the biological toll of breast cancer may be greater in black women than white women. Copyright © 2012 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

Abstract: Why does living in a disadvantaged neighborhood predict poorer mental and physical health? Recent research focusing on the Southwestern United States suggests that disadvantaged neighborhoods favor poor health, in part, because they undermine sleep quality. Building on previous research, we test whether this process extends to the Midwestern United States. Specifically, we use cross-sectional data from the Survey of the Health of Wisconsin (SHOW), a statewide probability sample of Wisconsin adults, to examine whether associations among perceived neighborhood quality (e.g., perceptions of crime, litter, and pleasantness in the neighborhood) and health status (overall self-rated health and depression) are mediated by overall sleep quality (measured as self-rated sleep quality and physician diagnosis of sleep apnea). We find that perceptions of low neighborhood quality are associated with poorer self-rated sleep quality, poorer self-rated health, and more depressive symptoms. We also observe that poorer self-rated sleep quality is associated with poorer self-rated health and more depressive symptoms. Our mediation analyses indicate that self-rated sleep quality partially mediates the link between perceived neighborhood quality and health status. Specifically, self-rated sleep quality explains approximately 20% of the association between neighborhood quality and self-rated health and nearly 19% of the association between neighborhood quality and depression. Taken together, these results confirm previous research and extend the generalizability of the indirect effect of perceived neighborhood context on health status through sleep quality. [Copyright &y& Elsevier]

Perceived discrimination is a potential cause of racial and ethnic disparities in health. Disturbed sleep may serve as a mechanism linking perceived racism with health consequences. This study investigates data from 7,148 adults from Michigan and Wisconsin who participated in the 2006 Behavioral Risk Factor Surveillance System. Hierarchical logistic regression analyses explored associations between perceived racial discrimination and self-reported sleep disturbance and daytime fatigue. Sleep disturbance and daytime fatigue were reported in 19% and 21% of the sample, respectively. Black/African American respondents (21%) report perceiving worse experiences, compared to people of other races, when seeking health care at higher rates than non-Hispanic White respondents (3%). Results from logistic regression models show that perceived racial discrimination is associated with increased risks of sleep disturbance (odds ratio [OR] = 2.62, p < .0001) and daytime fatigue (OR = 2.07, p < .0001). After adjustment for all covariates, perceived discrimination remains a significant predictor of sleep disturbance (OR = 1.60, p = .04). The interaction between perceived racism and race (Black/African American vs. non-Hispanic White) was nonsignificant. This population-based research adds to the growing body of data, suggesting that perceived racism may impact health via its influence on sleep-wake behaviors. [ABSTRACT FROM PUBLISHER]

To investigate the associations of caregiver-reported use of language-based bedtime routines among preschoolers at age 3 with children's nighttime sleep duration and cognitive, behavioral, and health outcomes at age 5. Furthermore, we wanted to identify whether parental or household characteristics help explain these associations. We used data on 4,274 children from birth to age 5, drawn from the Fragile Families and Child Wellbeing Study (FFCW), a longitudinal birth cohort study of at-risk children born between 1998 and 2000 in 20 U.S. cities. We used ordinary least squares (for continuous outcomes) and logistic regressions (for dichotomous outcomes) to estimate associations of language-based bedtime routines at age 3 with sleep duration and cognitive, behavioral, and health outcomes at age 5, net of a host of child and family background characteristics. After adjustment for child and family characteristics, we observed a positive association between language-based bedtime routines and both nighttime sleep duration and verbal test scores. Language-based bedtime routines were also inversely associated with behavior problems (anxious, withdrawn, and aggressive behaviors) and positively associated with better general health, yet adjustment for family background characteristics attenuated these associations. No associations were found between language-based bedtime routines and obesity. Results were confirmed using propensity score matching. This research suggests regular use of language-based bedtime routines including singing, reading, and/or storytelling at bedtime may have a lasting positive benefit for children's sleep duration and cognitive development; we find little evidence of such a benefit for child behavior or health. [ABSTRACT FROM AUTHOR]

Negative acculturation, the increase in high-risk profiles as immigrants live longer in the U.S., is found for a range of health behaviors and outcomes among Latino populations. Yet it has never been explored with regard to sleep duration. Using the National Health Interview Survey, we investigate Mexican immigrant and U.S.-born Mexican-American sleep durations. U.S.-born Mexican Americans are around 40% ( P < 0.05) more likely to be short sleepers than Mexican immigrants after adjusting for demographic characteristics. These relationships are attenuated with the addition of health behavior variables (OR = 1.25, n.s.). This is explained because U.S.-born Mexican Americans have higher rates of smoking and stress levels, both of which are associated with increased risks of short sleeping. Because chronic partial sleep deprivation may increase health risks directly and indirectly through impaired judgment, sleep may be a mechanism through which health disparities between Mexican immigrants and U.S.-born Mexican Americans emerge. [ABSTRACT FROM AUTHOR]

Objectives: We examine the association between perceived neighborhood disorder and self-rated physical health. Building on previous research, we test whether this association is mediated by sleep quality. Methods: We use data from the 2004 Survey of Texas Adults (n =1323) to estimate a series of ordinary least squares regression models. We formally assess mediation by testing for significant changes in the effect of neighborhood disorder before and after adjusting for sleep quality. Results: We find that residence in a neighborhood that is perceived as noisy, unclean, and crime-ridden is associated with poorer self-rated physical health, even with controls for irregular exercise, poor diet quality, smoking, binge drinking, obesity and a host of relevant sociodemographic factors. Our results also indicate that the relationship between neighborhood disorder and self-rated physical health is partially mediated by lower sleep quality. Conclusion: Targeted interventions designed to promote sleep quality in disadvantaged neighborhoods may help to improve the physical health of residents in the short-term. Policies aimed at solving the problem of neighborhood disorder are needed to support sleep quality and physical health in the long-term. [Copyright &y& Elsevier]

This paper addresses whether universal, general education programs are enough to satisfy basic criteria of human rights, or whether comprehensive family planning programs, in conjunction with universal education programs, might also be morally required. Even before the Reagan administration instituted the ‘global gag rule’ at the 1984 conference in Mexico City, prohibiting funding to nongovernmental organizations that included providing information about abortion as a possible method of family planning, the moral acceptability of family planning programs has been called into question. This paper makes a moral argument for family planning by appealing to both data and to theory: data about the efficacy of universal and comprehensive family planning education programs at reducing fertility and infant mortality, and theory about what is required for the establishment of autonomy. It reasons that universal educational programs are insufficient for the promotion of autonomy, and therefore argues on substantive autonomy grounds for comprehensive family planning programs in addition to universal education programs. [ABSTRACT FROM PUBLISHER]

Abstract: Background: Insomnia is the most commonly reported sleep disorder, characterized by trouble falling asleep, staying asleep, or waking up too early. Previous epidemiological data reveal that women are more likely than men to suffer from insomnia symptoms. We investigate the role that mental health history plays in explaining the gender disparity in insomnia symptoms. Methods: Using logistic regression, we analyze National Health and Nutritional Examination Survey (NHANES) III interview and laboratory data, merged with data on sociodemographic characteristics of the residential census tract of respondents. Our sample includes 5469 young adults (ages 20–39) from 1429 census tracts. Results: Consistent with previous research, we find that women are more likely to report insomnia symptoms compared to men (16.7% vs. 9.2%). However, in contrast to previous work, we show that the difference between women’s and men’s odds of insomnia becomes statistically insignificant after adjusting for history of mental health conditions (OR=1.08, p >.05). Conclusions: The gender disparity in insomnia symptoms may be driven by higher prevalence of affective disorders among women. This finding has implications for clinical treatment of both insomnia and depression, especially among women. [Copyright &y& Elsevier]

Turfgrass landscapes are commonly maintained using deficit irrigation. Here we follow-up a prior study, which surveyed turfgrass establishment in plots amended with biochar or compost or a mixture of both and unamended control plots. Following establishment, the plots were differentially irrigated at either full (85% ET o replaced) or deficit (50% ET o replaced) levels for four years and sampled for analysis. Relationships between soil chemical parameters and microbial community biomass and profiles based on phospholipid fatty acid analysis and high throughput sequencing of bacterial/archaeal 16S rRNA genes were determined. Compared to the unamended control soils, compost amended soils with or without biochar underwent greater shifts in soil physiochemical and biological properties than those receiving biochar. Although the impact of compost on the microbial community lessened with time, even 5 years after its incorporation, compost amended soils had increased microbial biomass by 127% and 157% in full and deficit irrigated plots compared to unamended plots. Bacterial/archaeal communities compositionally were more divergent in response to deficit irrigation in the unamended soils than in those amended with compost or biochar. Both soil amendments resulted in reduced relative abundances of nitrifying bacteria and archaea. In compost-amended soils many taxa associated with plant growth promotion and carbon cycling increased in relative abundance, whereas no such effect was observed with biochar. Altogether, these results provide mechanistic insights into how organic amendments affect turfgrass systems and their associated soil microbial communities under full and deficit irrigation regimens. [Display omitted] • Biochar and compost divergently impacted functional groups of soil taxa. • Deficit irrigation shifted community structures more-so in unamended soils. • Soil microbial community responses to compost persisted for 5 years. [ABSTRACT FROM AUTHOR]

Using high-quality longitudinal data on 125,720 singleton live births in Matlab, Bangladesh, we assessed the effects of duration of intervals between pregnancy outcomes on infant and child mortality and how these effects vary over subperiods of infancy and childhood and by the type of outcome that began the interval. Controlling for other correlates of infant and child mortality, we find that shorter intervals are associated with higher mortality. Interval effects are greater if the interval began with a live birth than with another pregnancy outcome. In the first week of the child's life, the effects of short intervals are greater if the sibling born at the beginning of the interval died; after the first month, the effects are greater if that sibling was still alive. Many relationships found are consistent with the maternal depletion hypothesis, and some with sibling competition. Some appear to be due to correlated risks among births to the same mother. [ABSTRACT FROM AUTHOR]

Infant and child mortality rates are significantly lower in the Maternal and Child Health-Family Planning (MCH-FP) area of Matlab, Bangladesh, than in a comparison area. The two areas are similar in terms of socioeconomic characteristics, but the MCH-FP area provides better maternal and child health and family planning services, resulting in different reproductive patterns, including lower fertility rates and longer intervals between pregnancies. We use data from the Matlab Demographic Surveillance System for nearly 126,000 singleton live births that occurred between 1982 and 2002 to investigate the extent to which the different reproductive patterns in the MCH-FP area explain why infant and child mortality rates are lower there. Differences in reproductive patterns account for a small portion (up to 20 percent) of the variation in these rates between the MCH-FP and comparison areas, suggesting that the majority of the difference is due to the quality of MCH services. [ABSTRACT FROM AUTHOR]

in this article, the authors test a "frog-pond" model of elite college admission proposed by Attewell, operationalizing high school academic context as the secondary school-average SAT score and number of Advanced Placement tests per high school senior. Data on more than 45,000 applications to three elite universities show that a high school's academic environment has a negative effect on college admission, controlling for individual students' scholastic ability. A given applicant's chances of being accepted are reduced if he or she comes from a high school with relatively more highly talented students, that is, if the applicant is a small frog in a big pond. Direct evidence on high school class rank produces similar findings. A school's reputation or prestige has a counterbalancing positive effect on college admission. Institutional gatekeepers are susceptible to context effects, but the influence of school variables is small relative to the characteristics of individual students. The authors tie the findings to prior work on meritocracy in college admission and to the role played by elite education in promoting opportunity or reproducing inequality, and they speculate on the applicability of frog-pond models in areas beyond elite college admission. [ABSTRACT FROM AUTHOR]

Soil extracellular polysaccharides (EPSac) can improve irrigation water productivity in agriculture by increasing soil aggregate stability and retaining water on and around plant roots. However, limited studies assay soil EPSac directly from field trials and to date no studies have examined the long-term confounding impacts of organic amendments and deficit irrigation on soil EPSac and the underlying microbial communities. We quantified soil aggregate stability, EPSac content, chemical properties, and microbial community compositions and abundances in separate field studies in turfgrass and tomato. Soil samples were collected 4–5 years after soil amendment with compost, biochar, their combination, or biosolids from plots that had received full and deficit irrigation regimens for 4 years. Amending the soil with compost, with or without biochar co-application, enhanced soil total carbon, aggregate stability, EPSac, and total soil microbial biomass and shifted microbial community structures, trends which were more pronounced under turfgrass than for tomato. In both sites deficit irrigation treatments had higher quantities of soil EPSac per unit of microbial biomass. Indicators of microbial physiological stress and ubiquitous classes of soil bacteria were associated with soil EPSac production. These results provide mechanistic understanding of organic amendment benefits in drought-impacted and deficit-irrigated agriculture. [Display omitted] • In a perennial system composts improved soil properties related to water productivity. • Comparatively in an annual system there were fewer benefits of composts or biochar. • Deficit irrigation increased extracellular polysaccharide: microbial biomass ratios. • Extracellular polysaccharides associated with ubiquitous soil bacterial taxa. [ABSTRACT FROM AUTHOR]

Prior studies have examined the cross-sectional relationship between adolescent sleep and substance use; however, fewer have explored the long-term connections between childhood sleep and adolescent substance use. This study investigated both cross-sectional associations during adolescence and prospective associations between childhood weeknight sleep and later alcohol and marijuana use in the Future of Families and Child Wellbeing Study, a diverse national birth cohort of urban children from 20 cities with populations greater than 200,000. Parents reported their child's bedtime at ages 3, 5, and 9 and their child's sleep duration at ages 5 and 9. At age 15, adolescents self-reported their bedtime, sleep duration, and alcohol and marijuana use (n = 1514). Logistic regression analyses for each substance use outcome at age 15 were adjusted for sex, age at time of assessment, race/ethnicity, income-relative-to-poverty threshold, family structure, and caregiver education level. At age 15, later bedtime (AOR=1.39; 95 % CI=1.22, 1.57) and shorter sleep duration (AOR=1.28; 95 % CI=1.14, 1.43) were associated with greater odds of consuming a full drink of alcohol more than once, and later bedtime was associated with greater odds of trying marijuana (AOR=1.35; 95 % CI=1.20, 1.51). Unexpectedly, later bedtimes at age 3 were associated with lower odds of drinking alcohol by age 15 (AOR=0.74; 95 % CI=0.59, 0.92). In contrast, later bedtimes at age 9 were associated with greater odds of drinking alcohol (AOR=1.45; 95 % CI=1.11, 1.90). Additionally, later bedtime at age 5 (AOR=1.26; 95 % CI=1.01, 1.58) and shorter sleep duration at age 9 (AOR=1.19; 95 % CI=1.04, 1.36) were associated with greater odds of trying marijuana. Conclusion: Taken together, these associations support the importance of protecting childhood sleep habits to reduce the likelihood of substance use starting as early as mid-adolescence. In this longitudinal cohort study, adolescents were more likely to have consumed alcohol or tried marijuana by age 15 if they had later bedtimes and shorter sleep duration during childhood and adolescence. Protecting sleep health throughout childhood may reduce the likelihood of substance use during early adolescence. [ABSTRACT FROM AUTHOR]

To investigate associations between perceived childhood neighborhood safety and sleep over the life course. Among a cohort of 1693 Black/African American women aged 23–35 years at enrollment (2010–2012), participants recalled neighborhood safety (safe vs. unsafe) when they were 5, 10, and 15 years old. Participants' mothers/caregivers and participants reported sleep-related health behaviors at age 5. We used ordinal logistic regression to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for sleep-related health behaviors (i.e., rarely/never or sometimes vs. mostly/always going to bed by 8:00 p.m., bed in a quiet room, bed in a dimly lit or unlit room), separately. Adulthood sleep duration and insomnia symptoms were reported at enrollment and over three follow-up periods. We applied generalized estimating equations to log binomial regression models to estimate relative risks (RR) for adulthood sleep characteristics. Four percent of participants reported an unsafe neighborhood at age 5 years, only, and 12% reported an unsafe neighborhood at all ages. Participants in perceived unsafe vs. safe neighborhoods at age 5 had higher odds of poor sleep-related health behaviors (e.g., rarely/never or sometimes going to bed in a quiet room: OR = 1.73 [1.27–2.35]). Participants in perceived unsafe vs. safe neighborhoods throughout childhood had higher risk of short sleep (RR = 1.10 [1.02–1.18]) and insomnia symptoms (RR = 1.07 [1.00–1.15]) during adulthood after adjustment for life course socioeconomic characteristics and adulthood health behaviors and characteristics. Perceived unsafe childhood neighborhood was associated with poorer sleep over the life course and may serve as an early intervention target. • We assessed perceived childhood neighborhood safety and life course sleep. • Perceived unsafe childhood neighborhood was associated with poor sleep in childhood. • Perceived unsafe childhood neighborhood was associated with poor sleep in adulthood. • Living in unsafe neighborhoods during childhood may impact life course sleep health. [ABSTRACT FROM AUTHOR]

The purpose of this study was to determine whether sleep characteristics are associated with incidence of treated diabetes in postmenopausal individuals. Postmenopausal participants ages 50-79 years reported sleep duration, sleep-disordered breathing, or insomnia at baseline and again in a subsample 3 years later. The primary outcome was self-reported new diagnosis of diabetes treated with oral drugs or insulin at any time after baseline. Multivariable Cox proportional hazards models were used. In 135,964 participants followed for 18.1 (± 6.3) years, there was a nonlinear association between sleep duration and risk of treated diabetes. Participants sleeping ≤5 hours at baseline had a 21% increased risk of diabetes compared with those sleeping 7 hours (adjusted hazard ratio [aHR] 1.21; 95% confidence interval [CI], 1.00-1.47). Those who slept for ≥9 hours had a nonsignificant 6% increased risk of diabetes compared with those sleeping 7 hours (aHR 1.06; 95% CI, 0.97-1.16). Participants whose sleep duration had decreased at 3 years had a 9% (aHR 1.09; 95% CI, 1.02-1.16) higher risk of diabetes than participants with unchanged sleep duration. Participants who reported increased sleep duration at 3 years had a risk of diabetes (HR 1.01; 95% CI, 0.95-1.08) similar to those with no sleep duration change. Participants at high risk of sleep-disordered breathing at baseline had a 31% higher risk of diabetes than those without (aHR 1.31; 95% CI, 1.26-1.37). No association was found between self-reported insomnia score and diabetes risk. Sleep-disordered breathing and short or long sleep duration were associated with higher diabetes risk in a postmenopausal population. [ABSTRACT FROM AUTHOR]

To assess the impact of a school start time (SST) delay on adolescent sleep health during the COVID-19 pandemic, and whether there were differences by learning modality. Data were collected from a longitudinal study evaluating sleep, education, and health among high school students in Georgia in 2020. Paired t-tests and multivariable linear regression analyses were conducted to examine changes in sleep duration and timing among 9th grade students (n = 134) and their association with the learning modality (remote vs. in-person learner). Students' school day wake times were 1.5 hours later, school night sleep duration was 1.2 hours longer, and social jetlag was 0.9 hours shorter after the school start time delay (all P <.05). The learning modality was a significant predictor of changes in sleep timing but was not associated with changes in sleep duration. Delayed school start time was associated with positive changes in adolescent sleep health during the COVID-19 pandemic. Sleep timing was affected by the learning modality, however in-person and virtual students had similar gains in sleep duration. Learning modality may be more beneficial for adolescents with early school start times to promote healthier sleep habits. [ABSTRACT FROM AUTHOR]

The athletic advantage of sleep, although commonly touted by coaches, trainers, and sports physicians, is still unclear and likely varies by sport, athletic performance metric, and length of sufficient or insufficient sleep. Although recent literature reviews have highlighted circadian and nutritional factors that influence different aspects of athletic performance, a systematic summary of the effects of sleep duration and sleep quality on performance among competitive athletes is lacking. Here we systematically review the relationship between sleep duration and sleep quality and objective athletic performance among competitive athletes across 19 studies representing 12 sports. Taken holistically, we find that the sports requiring speed, tactical strategy, and technical skill are most sensitive to sleep duration manipulations. Furthermore, longer-term sleep manipulations are more likely than acute sleep manipulations (whether deprivation or extension) to affect athletic performance. Thus, the importance of sleep for competitive athletes to achieve high performance is dependent on the demands of the sport as well as the length of sleep interventions. In light of the limited number of studies investigating sleep quality and performance, the potential relevance of subjective sleep quality remains an interesting question for future work. [ABSTRACT FROM AUTHOR]

Although numerous studies have shown that religious involvement is associated with better health across the life course, researchers have virtually ignored possible links between religious involvement and sleep-related outcomes. Building on previous work, we tested whether religious attendance is inversely associated with sleep disturbance among older Mexican Americans. We also assessed whether depressive symptoms mediate the association between religious attendance and sleep disturbance. Our mediation model was tested using ordinary least squares regression and conditional process analysis of cross-sectional data from the original cohort of the Hispanic Established Population for the Epidemiologic Study of the Elderly. Regression models show that religious attendance is inversely associated with depressive symptoms and sleep disturbance. Mediation analyses indicate that depressive symptoms mediate the association between religious attendance and sleep disturbance. These findings contribute to previous work by showing that religious attendance may protect against sleep disturbance by promoting mental health among older Mexican Americans. [ABSTRACT FROM AUTHOR]

Manure is a leading source of methane (CH4), nitrous oxide (N2O), and ammonia (NH3) emissions, and alternative manure management practices can help society meet climate goals and mitigate air pollution. Recent studies show that biochar‐composting can substantially reduce emissions from manure. However, most studies test only one type of biochar applied at a single application rate, leading to high variation in emission reductions between studies. Here, we measured greenhouse gas and NH3 emissions during biochar‐composting of dairy manure with biochar applied at 5% or 20%, by mass, and made from walnut shells, almond shells, or almond clippings. We found little difference in emissions between biochar type. However, we found that the 20% application rates increased CH4 emissions and decreased N2O and NH3 emissions, resulting in a net reduction in global warming potential (GWP). We attribute this result to biochar increasing the formation of compost aggregates, which likely acted as anaerobic reactors for methanogenesis and complete denitrification. Biochar may have further fueled CH4 production and N2O consumption by acting as an electron shuttle within aggregates. We recommend lower application rates, as we found that the 5% treatments in our study led to a similar reduction in GWP without increasing CH4 emissions. [ABSTRACT FROM AUTHOR]

Although short total sleep time (TST) is associated with increased anxious symptoms in adolescents, it is unknown whether social jetlag, a misalignment between sleep timing on the weekend and school week, is independently associated with anxious symptoms. In the current study, sleep timing, anxious symptoms, and demographic information were assessed from 3097 adolescents (48% female, mean ± SD age 15.59 ± .77 years) from the age 15 wave of the Fragile Families and Child Wellbeing Study. Social jetlag was calculated as the absolute value of the midpoint of sleep on the weekend minus the midpoint of sleep during the school week. Anxious symptoms were measured through the 6-item anxiety subscale of the Brief Symptom Inventory 18. We assessed associations between sleep variables and anxious symptoms using multiple linear regression. Adjusted analyses controlled for sex, race/ethnicity, age in years, body mass index percentile, number of other children below the age of 18 in the household, and primary caregiver (PCG) married/cohabiting with youth's biological parent, PCG employment status, PCG household income and PCG education level. In fully adjusted models (R2 = .034), school night TST (b = −.04, ∆R2 = .005, p < .001) was negatively associated with anxiety symptoms, while social jetlag (b = .04, ∆R2 = .009, p < .001) was positively and independently associated with anxiety symptoms. Findings indicate small associations of school night TST and social jetlag with anxious symptoms. Thus, maintenance of optimal emotional health in adolescents may require both sufficient sleep duration and regularity of sleep timing across the week. [ABSTRACT FROM AUTHOR]

A letter to the editor is presented that discusses fatigue in middle and old age.

Abstract: Bacteria are one of the most abundant and diverse groups of micro‐organisms and mediate many critical terrestrial ecosystem processes. Despite the crucial ecological role of bacteria, our understanding of their large‐scale biogeography patterns across forests, and the processes that determine these patterns lags significantly behind that of macroorganisms. Here, we evaluated the geographic distributions of bacterial diversity and their driving factors across nine latitudinal forests along a 3,700‐km north–south transect in eastern China, using high‐throughput 16S rRNA gene sequencing. Four of 32 phyla detected were dominant: Acidobacteria, Actinobacteria, Alphaproteobacteria and Chloroflexi (relative abundance > 5%). Significant increases in bacterial richness and phylogenetic diversity were observed for temperate forests compared with subtropical or tropical forests. The soil organic matter (SOM) mineralisation rate (SOMmin, an index of SOM availability) explained the largest significant variations in bacterial richness. Variation partition analysis revealed that the bacterial community structure was closely correlated with environmental variables and geographic distance, which together explained 80.5% of community variation. Among all environmental factors, climatic features (MAT and MAP) were the best predictors of the bacterial community structure, whereas soil pH and SOMmin emerged as the most important edaphic drivers of the bacterial community structure. Plant functional traits (community weighted means of litter N content) and diversity resulted in weak but significant correlations with the bacterial community structure. Our findings provide new evidence of bacterial biogeography patterns from tropical to cold temperate forests. Additionally, the results indicated a close linkage among soil bacterial diversity, climate and SOM decomposition, which is critical for predicting continental‐scale responses under future climate change scenarios and promoting sustainable forest ecosystem services. A plain language summary is available for this article. [ABSTRACT FROM AUTHOR]

Purpose: The goal of this study was to evaluate the relationships of actigraphic nighttime sleep duration and quality with next‐day mood among urban adolescents using a micro‐longitudinal design. Methods: A subsample (N = 525) of participants from the Fragile Families & Child Wellbeing Study (mean age: 15.4 years; 53% female; 42% Black non‐Hispanic, 24% Hispanic/Latino, 19% White non‐Hispanic) in the United States between 2014 and 2016 concurrently wore a wrist actigraphic sleep monitor and rated their daily mood in electronic diaries for about 1 week. Multilevel models tested the within‐person temporal associations of nightly sleep duration and sleep maintenance efficiency with next‐day reports of happiness, anger, and loneliness. The models also tested the between‐person associations of sleep variables and mood. Models adjusted for sociodemographic and household characteristics, weekend, and school year. Results: After nights when adolescents obtained longer sleep duration than their usual, they reported lower ratings of anger (B = –.03, p <.01) the next day. After nights when adolescents had higher sleep maintenance efficiency than their usual, they reported higher ratings of happiness (B =.02, p <.01) the next day. Adolescents who had longer average sleep duration reported lower ratings of anger (B = –.08, p <.01) and loneliness (B = –.08, p <.01) compared to others. There was no within‐person association of sleep duration or efficiency with loneliness. Sleep duration was not associated with happiness between adolescents, and sleep maintenance efficiency was not associated with any mood measure between adolescents. Conclusions: Improvements to nightly sleep may help increase happiness and decrease anger the following day in adolescents. Promoting sleep health is recommended to improve mood. [ABSTRACT FROM AUTHOR]

Financial stress has been linked to an increased risk of metabolic syndrome, yet, it remains unclear whether suboptimal sleep duration and physical inactivity are the adaptive responses to financial stress or effect modifiers in the association between financial stress and metabolic syndrome. Hence, this study aims to examine whether physical activity and sleep duration mediate or moderate the bivariate association between financial stress and metabolic syndrome. A prospective secondary analysis was conducted using data from the Wisconsin Sleep Cohort Study (N = 445, mean [SD] age = 64 [7] years). Baseline moderation effect was examined using subgroup analysis with model constraints; prospective mediation model was examined using bias‐corrected bootstrap confidence intervals. Results indicate that participants with higher financial stress were less likely to meet physical activity and sleep recommendations. Baseline moderation analysis indicates that meeting current recommendations of sleep duration and physical activity attenuated the association between financial stress and metabolic syndrome. In the prospective mediation analysis, weekly physical activity levels partially mediated the relationship between financial stress and metabolic syndrome, but sleep duration did not mediate this relationship. In conclusion, the joint effect of optimal sleep duration and physical activity disassociates financial stress from the risk of metabolic syndrome. Future interventions addressing metabolic risk might achieve better outcomes if clinicians and researchers factor in the behavioral adaptation of physical inactivity in financially stressed adults (Clinical Trial Registration: NCT00005557). [ABSTRACT FROM AUTHOR]

Summary: One model of a disease‐suppressive soil predicts that the confrontation of plant with a phytopathogen can lead to the recruitment and accumulation of beneficial microorganisms. However, more information needs to be deciphered regarding which beneficial microbes become enriched, and how the disease suppression is achieved.Here, we conditioned soil by continuously growing eight generations of cucumber inoculated with Fusarium oxysporum f.sp. cucumerinum in a split‐root system.Disease incidence was found to decrease gradually upon pathogen infection accompanied with higher quantity of reactive oxygen species (ROS mainly OH•) in roots and accumulation of Bacillus and Sphingomonas. These key microbes were proven to protect the cucumber from pathogen infection by inducing high ROS level in the roots through enrichment of pathways, including a two‐component system, a bacterial secretion system, and flagellar assembly revealed by metagenomics sequencing. Untargeted metabolomics analysis combined with in vitro application assays suggested that threonic acid and lysine were pivotal to recruit Bacillus and Sphingomonas.Collectively, our study deciphered a 'cry for help' case, wherein cucumber releases particular compounds to enrich beneficial microbes that raise the ROS level of host to prevent pathogen attack. More importantly, this may be one of the fundamental mechanisms underpinning disease‐suppressive soil formation. [ABSTRACT FROM AUTHOR]

Quantifying soil organic carbon ( SOC) decomposition under warming is critical to predict carbon-climate feedbacks. According to the substrate regulating principle, SOC decomposition would decrease as labile SOC declines under field warming, but observations of SOC decomposition under warming do not always support this prediction. This discrepancy could result from varying changes in SOC components and soil microbial communities under warming. This study aimed to determine the decomposition of SOC components with different turnover times after subjected to long-term field warming and/or root exclusion to limit C input, and to test whether SOC decomposition is driven by substrate lability under warming. Taking advantage of a 12-year field warming experiment in a prairie, we assessed the decomposition of SOC components by incubating soils from control and warmed plots, with and without root exclusion for 3 years. We assayed SOC decomposition from these incubations by combining inverse modeling and microbial functional genes during decomposition with a metagenomic technique (GeoChip). The decomposition of SOC components with turnover times of years and decades, which contributed to 95% of total cumulative CO2 respiration, was greater in soils from warmed plots. But the decomposition of labile SOC was similar in warmed plots compared to the control. The diversity of C-degradation microbial genes generally declined with time during the incubation in all treatments, suggesting shifts of microbial functional groups as substrate composition was changing. Compared to the control, soils from warmed plots showed significant increase in the signal intensities of microbial genes involved in degrading complex organic compounds, implying enhanced potential abilities of microbial catabolism. These are likely responsible for accelerated decomposition of SOC components with slow turnover rates. Overall, the shifted microbial community induced by long-term warming accelerates the decomposition of SOC components with slow turnover rates and thus amplify the positive feedback to climate change. [ABSTRACT FROM AUTHOR]

Obesity is one of the best-documented outcomes of screen media exposure. Many observational studies find relationships between screen media exposure and increased risks of obesity. Randomized controlled trials of reducing screen time in community settings have reduced weight gain in children, demonstrating a cause and effect relationship. Current evidence suggests that screen media exposure leads to obesity in children and adolescents through increased eating while viewing; exposure to high-calorie, low-nutrient food and beverage marketing that influences children's preferences, purchase requests, consumption habits; and reduced sleep duration. Some evidence also suggests promise for using interactive media to improve eating and physical activity behaviors to prevent or reduce obesity. Future interdisciplinary research is needed to examine the effects of newer mobile and other digital media exposures on obesity; to examine the effectiveness of additional interventions to mitigate the adverse effects of media exposures on obesity and possible moderators and mediators of intervention effects; to effectively use digital media interventions to prevent and reduce obesity; and to uncover the mechanisms underlying the causal relationships and interactions between obesity-related outcomes and media content, characteristics, and context. [ABSTRACT FROM AUTHOR]

A letter to the editor is presented in response to the article "Cross-sectional and Longitudinal Associations Between Objectively Measured Sleep Duration and Body Mass Index: The CARDIA Sleep Study," by D. S. Lauderdale, K. L. Knutson and P. J. Rathouz in the 2009 issue of the "American Journal of Epidemiology."

Objectives: To evaluate sleep and affective (mood/anxiety) disorders as clinical predictors of incident Parkinson's disease (PD) among women ≥65 years of age.Methods: We performed secondary analyses with available data from the Women's Health Initiative Clinical Trials and Observational Study linked to Medicare claims. Sleep, mood and anxiety disorders at baseline were defined using diagnostic codes. Incident PD was defined using self-reported PD, first PD diagnosis, use of PD medications, and/or deaths attributed to PD. Cox regression was applied to estimate hazard ratios (HR) with 95 % confidence intervals (CI), controlling for socio-demographic/lifestyle/health characteristics. Time-to-event was calculated from baseline (1993-1998) to year of PD event, loss to follow-up, death, or December 31, 2018, whichever came first.Results: A total of 53,996 study-eligible WHI participants yielded 1756 (3.25 %) PD cases over ~14.39 (±6.18) years of follow-up. The relative risk for PD doubled among women with affective disorders (HR = 2.05, 95 % CI: 1.84, 2.27), mood disorders (HR = 2.18, 95 % CI: 1.97, 2.42) and anxiety disorders (HR = 1.97, 95 % CI: 1.75, 2.22). Sleep disorders alone (without affective) were not significantly associated with PD risk (HR = 0.85, 95 % CI: 0.69, 1.04), whereas affective disorders alone (without sleep) (HR = 1.93, 95 % CI: 1.72, 2.17) or in combination with sleep disorders (HR = 2.18, 95 % CI: 1.85, 2.56) were associated with twice the PD risk relative to no sleep/affective disorders.Limitations: Observational design; Selection bias; Information bias; Generalizability.Conclusions: Among older women, joint sleep/affective disorders and affective disorders alone are strong clinical predictors of incident PD over 14 years. [ABSTRACT FROM AUTHOR]

Objectives/Background We assessed prevalence and correlates of insomnia; associations between changes in insomnia with incidence of physical, emotional, and mixed impairments (PI, EI, and MI, respectively); and age as a moderator in these relationships. Participants/Methods The Women's Health Initiative (WHI) clinical trial (CT) and observational study (OS) cohorts with 1- and 3-year follow-ups, respectively, were studied. Participants included 39,864 CT and 53,668 OS postmenopausal women free of PI or EI at baseline. Insomnia Rating Scale (IRS), with a cutoff score of ≥9 indicated insomnia. Normal–Normal, Abnormal–Abnormal, Normal–Abnormal, and Abnormal–Normal categories indicated change in insomnia over time. PI, EI, and MI were constructed using Short Form-36 (SF-36) Physical and Emotional subscales (cutoff ≤60) and the modified Center for Epidemiological Studies Depression scale (cutoff ≤0.06). Results Among 93,532 women, 24.5% had insomnia at baseline. The highest odds ratios (ORs) for impairments were found in the Normal–Abnormal and Abnormal–Abnormal categories. In the CT cohort, Normal–Abnormal category, ORs were 1.86 (95% CI = 1.57–2.20) for PI, 4.11 (95% CI = 3.59–4.72) for EI, and 6.37 (95% CI = 4.65–8.74) for MI. Respective ORs for the OS cohort were 1.70 (95% CI = 1.51–1.89), 3.80 (95% CI = 3.39–4.25), and 4.41 (95% CI = 3.56–5.46). Interactions between changes in insomnia and age showed distinct albeit nonsignificant patterns. Conclusions The results suggest that exposure to insomnia increases vulnerability to impairment. Future studies are needed to understand the directionality of these relationships. [ABSTRACT FROM AUTHOR]

Rahnella aquatilis strain HX2 has the ability to promote maize growth and suppress sunflower crown gall disease caused by Agrobacterium vitis, A. tumefaciens, and A. rhizogenes. Pyrroloquinoline quinone (PQQ), a cofactor of aldose and alcohol dehydrogenases, is required for the synthesis of an antibacterial substance, gluconic acid, by HX2. Mutants of HX2 unable to produce PQQ were obtained by in-frame deletion of either the pqqA or pqqB gene. In this study, we report the independent functions of pqqA and pqqB genes in relation to PQQ synthesis. Interestingly, both the pqqA and pqqB mutants of R. aquatilis eliminated the ability of strain HX2 to produce antibacterial substance, which in turn, reduced the effectiveness of the strain for biological control of sunflower crown gall disease. The mutation also resulted in decreased mineral phosphate solubilization by HX2, which reduced the efficacy of this strain as a biological fertilizer. These functions were restored by complementation with the wild-type pqq gene cluster. Additionally, the phenotypes of HX2 derivatives, including colony morphology, growth dynamic, and pH change of culture medium were impacted to different extents. Our findings suggested that pqqA and pqqB genes individually play important functions in PQQ biosynthesis and are required for antibacterial activity and phosphorous solubilization. These traits are essential for R. aquatilis efficacy as a biological control and plant growth promoting strain. This study enhances our fundamental understanding of the biosynthesis of an environmentally significant cofactor produced by a promising biocontrol and biological fertilizer strain. [ABSTRACT FROM AUTHOR]

Background: Poor self-reported sleep health has been linked to not consuming breakfast in adolescents, but it is unknown whether poor sleep measured objectively predicts next-day breakfast consumption within adolescents. We investigated within- and between-person associations of objectively measured sleep dimensions and subjective sleep quality with adolescent breakfast consumption. Methods: Data were collected from a micro-longitudinal substudy of the Year 15 wave of the Fragile Families and Child Wellbeing Study (n = 590). Adolescents wore an actigraphy device and completed daily diaries for ~ 1 week (M ± SD = 5.6 ± 1.4 nights per adolescent, range: 3–9), where they rated their sleep quality and reported whether they had eaten breakfast that day, with no specific definition of breakfast provided (M ± SD = 5.5 ± 1.4 days per adolescent, range: 3–9). Separate mixed models assessed whether actigraphy-measured sleep duration (linear and quadratic, sleep duration x sleep duration), timing, maintenance efficiency, and subjective quality predicted odds of breakfast consumption both within and between adolescents. Variability of sleep duration and timing (standard deviation per person), sleep regularity index (SRI), and social jetlag were tested as additional between-person predictors. Analyses with predictors other than sleep duration were adjusted for sleep duration. Results: Following nights when adolescents had shorter or longer sleep duration (p =.005; curvilinear association), later sleep onset, or later sleep midpoint (both p =.025) than their own usual, they had lower odds of consuming breakfast the next day (within-person associations). Adolescents who on average had later sleep onset (p =.013) or midpoint (p =.013) or who reported lower sleep quality (p =.011) had lower average odds of consuming breakfast (between-person associations). Adolescents with greater variability of sleep duration (p =.005), midpoint (p =.004), or offset (p <.001) had lower average odds of consuming breakfast (between-person associations). Sleep maintenance efficiency (within or between adolescents), SRI, and social jetlag were not associated with breakfast consumption (all p >.10). Conclusions: Multiple dimensions of sleep health are associated with breakfast consumption, both within and between adolescents. Poor sleep and dietary behaviors in adolescence may negatively impact future metabolic health. [ABSTRACT FROM AUTHOR]