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In the continuous setting, Morrey spaces have been studied extensively, especially since the late 1960s. Meanwhile, Morrey sequence spaces, which are also known as discrete Morrey spaces, have only been developed by Gunawan et al. since 2018. In this article, we extend some known results on their inclusion properties and their (lack of) uniform nonsquareness to mixed Morrey double-sequence spaces, i.e. Morrey double-sequence spaces equipped with a mixed norm. As in the calculation of three geometric constants of Morrey spaces by Gunawan et al. in 2019, we also compute three geometric constants, namely Von Neumann-Jordan constant, James constant, and Dunkl-Williams constant for mixed Morrey double-sequence spaces. These constants measure uniformly nonsquareness of any Banach space. Through the values of the three constants, we reveal that mixed Morrey double-sequence spaces are not uniformly nonsquare. A relation between mixed Morrey double-sequence spaces and mixed Morrey spaces is also discussed. [ABSTRACT FROM AUTHOR]

Introduction: Leprosy is a chronic granulomatous infectious disease, mainly affecting the skin and peripheral nerves, caused by the obligate intracellular bacteria Mycobacterium leprae. The disease has been discussed in several review articles in recent research, but as far as we know, only a few have addressed the effects of leprosy on nails, especially those who examine the dermoscopic features of nails in leprosy patients. Purposes: We aimed to document nail changes in leprosy patients and identify any particular findings through dermoscopic examination. Method: This was an observational study conducted in the Dermatology and Venereology Clinic of Hasan Sadikin Hospital, West Java, Indonesia, from March 2023 through May 2023. All patients have established cases of leprosy, and the diagnosis is based on clinical and bacteriological examinations. Recruitment was done through total sampling. Dermoscopic examination of all fingernails and toenails was performed at 10x magnification using a handheld dermatoscope (Heine DELTA 20 T Dermatoscope) in polarized mode without the linkage fluid to document the dermoscopic features. Result: Of a total of 19 patients, 15 had nail changes due to leprosy. Out of 15 patients, 13 patients were male. Patients below 25 years old had more nail changes. Most of the patients had a duration of disease greater than two years. Both fingers and toes were involved in nine patients. In this study, the most common dermoscopic feature found was the longitudinal ridge. Other dermoscopic features found in this study were transverse lines, onycholysis, longitudinal melanonychia, leukonychia, subungual hemorrhage, subungual hyperkeratosis, anonychia, and onychorrexis. Conclusion: Nail changes are found in leprosy patients and have a wide variety of clinical appearances. A dermoscopy should be performed to assess nail changes in leprosy. [ABSTRACT FROM AUTHOR]

We discuss a necessary condition for inclusion relations of weak type discrete Morrey spaces which can be seen as an extension of the results in [H. Gunawan, E. Kikianty and C. Schwanke, Discrete Morrey spaces and their inclusion properties, Math. Nachr. 291 2018, 8–9, 1283–1296] and [D. D. Haroske and L. Skrzypczak, Morrey sequence spaces: Pitt's theorem and compact embeddings, Constr. Approx. 51 2020, 3, 505–535]. We also prove a proper inclusion from weak type discrete Morrey spaces into discrete Morrey spaces. In addition, we give a necessary condition for this inclusion. Some connections between the inclusion properties of discrete Morrey spaces and those of Morrey spaces are also discussed. [ABSTRACT FROM AUTHOR]

Background: A decision to diagnose certain skin diseases in patient undergoing psychotic break is challenging; this includes establishing the diagnosis of leprosy. Diagnosis of leprosy is established if there is at least one of the three cardinal signs of leprosy. Histopathological examination is not a gold standard, but remains useful in atypical or clinically suspicious cases.Case Presentation: We report for the first time, an interesting case of leprosy with atypical clinical manifestations in a psychotic homeless male with unknown history of present illness. Upon examination, hypopigmented macules, hyperpigmented macules, and plaques were observed, with unclear sensation impairment. Peripheral nerve thickening and acid-fast bacilli from slit-skin smear were not found. Histopathological examination from hypopigmented macule on the upper right limb showed no granulomatous reaction and other histopathological features of leprosy. Although the condition did not fulfill the cardinal signs of leprosy, we found lagophthalmos, claw hands, pseudomutilation of fingers and toes. Therefore, the diagnosis of suspected leprosy was established. The patient was hospitalized and attempts to administer oral rifampicin and clofazimine were made. Several days after treatment, annular erythematous macules appeared on the patient's face, abdomen, and back. Histopathological examination results on sample taken from erythematous macule and right sural nerve were consistent with the diagnosis of leprosy with reversal reaction.Conclusion: In certain conditions, histopathological examination of the skin and nerves are a highly rewarding test in establishing a diagnosis of leprosy. [ABSTRACT FROM AUTHOR]

We introduce a new 2-norm on a normed space using a semi-inner product g on the space. Using this 2-norm, we propose a formula for the g-angle between 2-dimensional subspaces in the space. Our formula serves as a revision of the one proposed by Nur et al. (Beitr. Algebra Geom. 59(1):133–143, 2018). [ABSTRACT FROM AUTHOR]

• Testicular damage may occur before and while taking antileprotic treatment. • Testicular involvement in leprosy might occur in the absence of signs and symptoms. • The assessment of testicular function should be recommended as a routine work-up for leprosy patients. Testicular involvement or atrophy in leprosy is silent, unreported, and under-estimated. The aim of this study was to assess the frequency of testicular atrophy and its consequences through the examination of clinical manifestations, hormonal profile, and semen analysis in leprosy patients. A descriptive observational study using a cross-sectional design and consecutive sampling method was conducted from May to July 2018. The study was conducted in Dr. Hasan Sadikin General Hospital, Bandung, Indonesia and included 32 men affected by leprosy and five healthy men as a control group. All patients were subjected to history-taking, dermatological and genital examinations, assessment of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone, and testicular ultrasonography examination. Semen analysis was performed for the 10 patients who consented. Testicular atrophy was observed in 93.75% of patients. Clinical manifestations of testicular atrophy were loss of libido (21.87%), female pubic hair pattern (9.38%), gynecomastia (6.25%), and secondary infertility (6.25%). Hormonal imbalance was seen in 16 patients, and all 10 patients who underwent semen analysis showed an abnormality. This study showed a high frequency of testicular atrophy, but the symptoms were only present in a few of patients. The assessment of testicular function should be recommended as a routine work-up for leprosy patients. [ABSTRACT FROM AUTHOR]

In this paper, we study relations between inner products derived from the standard n-inner product defined on an inner product space. In particular, we are interested in knowing when orthogonality with respect to the original inner product is preserved by the derived inner product. [ABSTRACT FROM AUTHOR]

A small phreatic eruption of Sinabung Volcano, North Sumatra on 28 August 2010, at 18:30 local time marked the first eruption in the past ~ 1200 years. The eruption took place from two small vents in the south crater area. Explosions and ash emissions from these vents generated multiple ash plumes that reached altitudes of up to 5 km during early- to mid-September. By the end of September 2010, only low level steam plumes were visible and the alert level was reduced from Level 4 (highest) to Level 3. The 2010 eruption effectively ended at this time. Beginning two days after the initial 2010 eruption, activity of the eruption has been monitored continuously by a telemetered seismic network surrounding the volcano and by remotely sensed observations. This monitoring system was supplemented with a near-field continuous GPS network, beginning in February 2011. Persistent fumarolic emissions continued for almost 3 years following the 2010 eruption, before a new eruption began on 15 September 2013. This eruption continues to the present. The ongoing eruption is divided into 5 major phases: 1) phreatomagmatic phase (July 2013–18 December 2013); 2) first dome and collapse phase with pyroclastic density currents (PDCs; block-and-ash flows and related surges) to south (18 December 2013–10 January 2014); 3) lava-flow and collapse phase (10 January 2014–mid-September 2014); 4) second lava dome and collapse phase with PDCs to south (mid-September 2014–July 2015); 5) lava dome collapse and ash explosion phase with PDCs to southeast and east (August 2015–present). The volcano erupted intermittently during the early phreatomagmatic phase with small vertical ash explosions. Then the eruption became increasingly vigorous with more repetitive and intense vertical ash explosions during late October through November. The first small pyroclastic density currents (PDCs) began on November 1. These pyroclastic flows descended the southeastern flank to a distance of 2 km. Swarms of volcano-tectonic (VT) earthquakes and volcanic tremor lasting hours occurred repeatedly during the phreatomagmatic phase and some of these VT-swarms were followed by explosions. In early December 2013, during the transition between phreatomagmatic and dome-collapse phases, swarms of hybrid earthquakes took place preceding and accompanying dome growth. The first lava dome was observed in satellite images on 18 December near the main crater rim. Partial collapses of the dome produced PDCs beginning on 30 December. Growth of this first lava dome continued into January and was accompanied by additional collapses and PDCs. By about 10 January, the lava had transitioned from a summit dome morphology into a lava flow morphology. The resulting lava flow descended the southeast flank of the volcano, producing flow-front and marginal collapses with associated PCDs. One such flow-flank collapse on 2 February 2014 resulted in a PCD that killed 16. The lava flow phase continued through mid-September 2014, when a second summit lava dome began to grow and collapse, producing PDCs initially to the south and southeast, and then beginning in July 2015 to the east and southeast. The eruption of Sinabung resulted in major impacts on the population of the resort and farming area near the volcano and in the Ginting and Karo Regencies of North Sumatra. Local residents, having not experienced eruptions in their lifetimes, were initially curious and eager to receive any information about the eruption regardless of its source. Various institutions provided information with little coordination, resulting in confusion. With time communications have improved and communities and the responsible governments have become better prepared in dealing with the persistent eruption. The Government of Indonesia has provided funding to support villagers who lived within a 5 km radius danger zone to stay in relocation camps as a permanent relocation area is being identified. Unfortunately, on 21 May 2016, 9 additional fatalities took place in the village of Gamber, within the danger zone, when a dome collapse sent a pyroclastic density current into the area. Throughout the eruption, the volcano has been monitored by the Indonesian Center for Volcanology and Geologic Hazard Mitigation (CVGHM) in partnership with the USGS-USAID Volcano Disaster Assistance Program and the Disaster Prevention Research Institute of Kyoto University. Monitoring techniques have included seismic, geodetic, gas, satellite and field observations, as well as occasional sampling of ash and lava for geochemical analyses. In this paper, we summarize key aspects of the monitoring data, their interpretations and their use in forecasting eruptive behavior and in issuance of alerts and warnings. More detailed interpretations of the monitoring data and their use are found in other papers of this special issue. • In this introductory paper to the Special Issue on the eruptions of Sinabung and Kelud volcanoes, we focus on the 2010 and 2013–present eruptions of Sinabung volcano, North Sumatra, Indonesia. • We provide information on the monitoring system used and we highlight how the monitoring data (seismic, geodetic, gas and observations) were used to forecast activity and to issue alerts and warnings. • We also describe the chronology of the 2013-present eruption and we review how the eruption has impacted the lives of residents of the region. [ABSTRACT FROM AUTHOR]

• The recent eruptions of Sinabung and Kelud volcanoes, contrast in both eruption style and crisis response. • This volume provides a wide range of volcanologic information on recent eruptions of Sinabung and Kelud. • Discussions of volcanology, petrology, geochemistry, remote sensing and the social response to the eruptions are included. [ABSTRACT FROM AUTHOR]

One of the success indicators of the World Health Organization (WHO) leprosy eradication program is the decreasing number of new cases of pediatric leprosy with a grade 2 disability. A case of borderline lepromatous (BL) leprosy with partial claw hand in a 13-year-old boy was reported. On physical examination, we found claw fingers on the fourth and fifth fingers of the left hand accompanied by hypoesthetic erythematous plaques on both cheeks. The patient also presented with the enlargement of bilateral great auricular, ulnar, and peroneal nerves. The bacteriological examination showed the bacterial index 3+ and morphological index 35%. The results of histopathological and serological anti-phenolic glycolipid-I examinations supported the diagnosis of BL type of leprosy. Genotyping of Mycobacterium leprae by variable number tandem repeat of the patient showed 24 copies thymine-thymine-cytosine that were similar to his father, who had been diagnosed with leprosy 12 years before, without adequate therapy. The result indicated the possibility of leprosy transmission from the father to a son. This case report revealed the presence of leprosy in children with a multibacillary infection who have been living with leprosy family members. Genotyping seems to be feasible for epidemiological analysis of leprosy transmission. [ABSTRACT FROM AUTHOR]

We use the Morrey norm estimate for the imaginary power of the Laplacian to prove an interpolation inequality for the fractional power of the Laplacian on Morrey spaces. We then prove a Hardy-type inequality and use it together with the interpolation inequality to obtain a Heisenberg-type inequality in Morrey spaces. [ABSTRACT FROM AUTHOR]

Abstract: We discuss discrete Morrey spaces and their generalizations, and we prove necessary and sufficient conditions for the inclusion property among these spaces through an estimate for the characteristic sequences. [ABSTRACT FROM AUTHOR]

Abstract: We establish the boundedness and weak boundedness of the maximal operator and generalized fractional integral operators on generalized Morrey spaces over metric measure spaces ( X , d , μ ) without the assumption of the growth condition on μ. The results are generalization and improvement of some known results. We also give the vector‐valued boundedness. Moreover we prove the independence of the choice of the parameter in the definition of generalized Morrey spaces by using the geometrically doubling condition in the sense of Hytönen. [ABSTRACT FROM AUTHOR]

At the moment, there are two main methods of solving the compressive sensing (CS) reconstruction problem which are the convex optimization and the greedy algorithm. Convex optimization has good reconstruction stability but very slow in computation. Greedy algorithm, on the other hand, is very fast but less stable. A fast and stable CS reconstruction algorithm is necessary for a better provision of CS in practical application. In this paper we proposed a CS reconstruction algorithm using L1-norm minimization via L2-norm minimization. This method is based on geometrical interpretation of L1-norm minimization of the reconstruction problem and the fact that the Euclidean distance between L1-norm and L2-norm solution lie closely. In other word, if L2-norm solution is found, then direction to the L1-norm solution is on the shortest path connecting them. This approach offers a simpler computation. Computer simulation showed that proposed algorithm has better stability than the greedy algorithm and faster computation than the convex optimization. The proposed algorithm thus provides an alternative solution for CS reconstruction problem when a balance between speed and stability is required. [ABSTRACT FROM AUTHOR]

In this paper, the size of the embedding constant from weak Morrey spaces into Morrey spaces is specified. As a by-product, the difference between weak Morrey spaces and Morrey spaces is clarified. [ABSTRACT FROM AUTHOR]

Objective. This study aimed to compare cathelicidin levels in the skin of leprae patients and leprae contacts. Patients and Methods. This research is an analytic observational study with a cross-sectional approach. Fifty-four research subjects participated in this study. They consisted of leprae patients, household contacts, and healthy individuals. Cathelicidin levels were measured using the ELISA method. Data analysis was carried out with the help of SPSS software, and univariate and bivariate analysis was conducted. Results. Cathelicidin levels in the leprae group (256.8±22.9 pg/ml) were higher than in the contact group (25.9±2.7 pg/ml). Likewise, the contact group had higher cathelicidin levels than healthy controls (1.4±0.1 pg/ml). Statistically, there were differences in cathelicidin levels between groups, P<0.050. Conclusion. Cathelicidin levels in leprae patients were higher than those in household contacts. [ABSTRACT FROM AUTHOR]

This paper discusses the structure of Morrey spaces, weak Morrey spaces, generalized Morrey spaces, and generalized weak Morrey spaces. Some necessary and sufficient conditions for the inclusion property of these spaces are obtained through a norm estimate for the characteristic functions of balls. [ABSTRACT FROM AUTHOR]

In this paper we discuss the structure of Orlicz spaces and weak Orlicz spaces on ℝn. We obtain some necessary and sufficient conditions for the inclusion property of these spaces. One of the keys is to compute the norm of the characteristic functions of the balls in ℝn. [ABSTRACT FROM AUTHOR]

Introduction: Indonesia is the most populous Muslim-majority country, where some women wear hijab covering their scalp and neck. Some hijab-wearing women complain of scalp problems eg, itch, dandruff, and hair loss, which might be related to severe and chronic skin barrier impairment due to occlusion. Excessive water accumulation in the occluded stratum corneum might result in increased permeability, followed by increased skin pH values. This study aimed to evaluate scalp hydration and pH values in hijab-wearing and non-hijab-wearing women.Material and Methods: This was a cross-sectional comparative analytical study using stratified random sampling methods conducted on 63 subjects, who were divided into two groups, consisting of 33 hijab-wearing and 30 non-hijab-wearing women. Both groups underwent physical examination and their medical history recorded. Scalp hydration was measured using a Corneometer (Courage + Khazaka, Koln, Germany), and scalp pH value was measured using a Skin & Scalp pH Tester (Hanna Instruments® HI981037, Rumania). This study was conducted at the Dermatology and Venereology Clinic of Hasan Sadikin General Hospital Bandung.Results: The mean scalp hydration and pH values were 18.34 ± 2.91 AU and 4.93 ± 0.17, respectively, in hijab-wearing women. Meanwhile, the mean scalp hydration and pH values were 17.71 ± 3.35 AU and 4.91 ± 0.16, respectively, in non-hijab-wearing women. The difference of scalp hydration and pH values between the groups was not statistically significant based on the independent t-test, with p-values of 0.430 and 0.597, respectively.Conclusion: Scalp hydration and pH values in hijab-wearing and non-hijab-wearing women did not differ significantly. Hijab-wearing women should not worry about scalp barrier impairment as long as they do not have any history of underlying scalp and skin disorders, and do not wear hijab in wet condition. [ABSTRACT FROM AUTHOR]

In this paper we prove Fefferman's inequalities associated to potentials belonging to a generalized Morrey space or a Stummel class. We also show that the logarithm of a non-negative weak solution to a second order elliptic partial differential equation with potential in a generalized Morrey space or a Stummel class, under some assumptions, belongs to the bounded mean oscillation class. As a consequence, this elliptic partial differential equation has the strong unique continuation property. An example of an elliptic partial differential equation with potential in a Morrey space or a Stummel class which does not satisfy the strong unique continuation is presented. [ABSTRACT FROM AUTHOR]

We prove weak type inequalities for some integral operators, especially generalized fractional integral operators, on generalized Morrey spaces of nonhomogeneous type. The inequality for generalized fractional integral operators is proved by using two different techniques: one uses the Chebyshev inequality and some inequalities involving the modified Hardy-Littlewood maximal operator and the other uses a Hedberg type inequality and weak type inequalities for the modified Hardy-Littlewood maximal operator. Our results generalize the weak type inequalities for fractional integral operators on generalized non-homogeneousMorrey spaces and extend to some singular integral operators. In addition, we also prove the boundedness of generalized fractional integral operators on generalized non-homogeneous Orlicz-Morrey spaces. [ABSTRACT FROM AUTHOR]

We revisit the Stummel class and its relation with Morrey spaces. We reformulate a result of Ragusa and Zamboni [11] and then discuss its generalization, as proposed by Eridani and Gunawan [4]. An improvement of the results previously obtained by Eridani and Gunawan is obtained and some extensions are presented. [ABSTRACT FROM AUTHOR]

Let Tp be the generalized fractional integral operator associated to a function ρ : (0,∞) → (0,∞), as defined in [16]. For a function W on ℝn, we shall be interested in the boundedness of the multiplication operator f ↦ W ·Tpf on generalized Morrey spaces. Under some assumptions on ρ, we obtain an inequality for W · Tρ, which can be viewed as an extension of Olsen's and Kurata-Nishigaki-Sugano's results. [ABSTRACT FROM AUTHOR]

Background: Pollen is an important trigger of seasonal rhinitis, conjunctivitis, and/or allergic asthma, and an exacerbating factor in atopic dermatitis. Pollen grains contain allergen proteins, enzymes, and bioactive lipid mediators, the latter two possibly involved in the pathogenesis of allergic diseases through IgE-independent mechanisms. Methods: We analyzed the patterns of release of endopeptidases from allergenic pollen of Japanese cedar, Japanese cypress, and Rocky mountain juniper, which belong to the Cupressaceae/Taxodiaceae family, and birch, ragweed, and two grasses, Kentucky blue and cultivated rye, using synthetic substrates, class-specific inhibitors, and zymography. The proteins released were analyzed by gel electrophoresis. Eicosanoid-like substances were measured by enzyme-linked immunosorbent assays for prostaglandin E2 and leukotriene B4. Results: Major fractions of proteins, eicosanoid-like substances, and at least one molecular species of serine endopeptidase were released into phosphate-buffered saline from the pollen grains at 37°C within 25 min or 60 min without sonication. In the Cupressaceae/Taxodiaceae family, sonication was necessary for the release of other proteins and another serine endopeptidase. In birch, ragweed, and the grasses, most of the serine and cysteine endopeptidases were released without sonication. Proteases released within 25 min digested gelatin and/or casein differently among plant species. Conclusions: Grains of allergenic pollen release proteases, which can digest not only short synthetic substrates but also protein substrates, along with eicosanoid-like substances and proteins. The release of these components could contribute to the formation of a microenvironment optimum for initiation of the sensitization or the exacerbation of pollen allergy in tissues exposed to pollen grains. Copyright © 2008 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

Background: Pollen is an important trigger of allergic rhinitis, conjunctivitis, and/or asthma, and an exacerbating factor in atopic dermatitis. Although it is proposed that protease activity from allergen sources, such as mites, enhances allergenicity, little information is available on that from relevant allergenic pollens such as Japanese cedar and Japanese cypress pollens, which are the major cause of pollinosis in Japan. Methods: We analyzed the protease activities derived from allergenic pollen of Japanese cedar, Japanese cypress, and Rocky mountain juniper, which belong to the Cupressaceae/Taxodiaceae family, and white birch and short ragweed, using synthetic substrates and class-specific inhibitors. Results: We found that the pollen of the three members of the Cupressaceae/Taxodiaceae family contained serine protease activity, that the pollen of white birch and short ragweed contained not only serine protease activity but also cysteine protease activity, that all five types of pollen tested contained at least one other type of serine protease, whose sensitivity to a serine protease-specific inhibitor was relatively low, and that the content and releasability of the pollen-derived proteases differed according to the plant families. Conclusions: Clinically relevant allergenic pollens tested in the present study can release serine and/or cysteine endopeptidases. Information on the spectrum of the endopeptidase activities from these allergenic pollen grains will be useful for investigating their contribution to the pathogenesis of allergies. [ABSTRACT FROM AUTHOR]

In this paper, we present some generalization of Ragusa and Zamboni's results on Stummel class and Morrey spaces. [ABSTRACT FROM AUTHOR]

The high rate of deforestation and fragmentation of elephant habitat on Sumatra Island has triggered human-elephant conflict (HEC) in Sumatra Island, Indonesia. This conflict brings negative impacts on humans and elephants. Despite numerous efforts having been made to solve this problem, the HEC continues to occur in the remaining elephant enclave every year. The harmonious coexistence between humans and elephants could be improved through HEC mitigation programs. The aim of this paper was to review information on HEC in Sumatra Island, investigate the causes and implications of HEC, review existing HEC mitigation methods, and formulate strategies to improve the harmonious coexistence between humans and elephants. The best strategies to create successful human and elephant coexistence are strengthening the institutions and policies, restoring the habitat, developing wildlife corridors, establishing Essential Ecosystem Areas (EEA), community empowerment through ecotourism, providing legal access to forests through Social Forestry (SF), and providing compensation schemes for conflict victims. [ABSTRACT FROM AUTHOR]

Despite a large amount of information being published on the decline in orangutan populations, there is far less on the actions being taken to address the underlying reasons, which are the loss and degradation of their habitat, hunting, and fires. There is also limited understanding of the complementary role played by different parties conducting conservation efforts on the ground. Here we address this by describing the conservation programmes of the Orangutan Foundation that have developed over the past three decades to support the Indonesian government's efforts to conserve the Bornean Orangutan in Central Kalimantan Province, Indonesian Borneo. These programmes, which are mutually synergistic in a holistic approach to orangutan conservation, cover habitat and species protection in conservation areas, landscape conservation outside conservation areas, rescues of orangutans in danger and translocations to protected forests, restoration of degraded forest habitat, research, education and awareness, community involvement, and coordination with stakeholders. The achievements of these programmes are described, with a particular focus on the Lamandau Wildlife Reserve. The collaboration with the Ministry of Environment and Forestry's national and regional conservation agencies and related stakeholders shows how major progress can be made through a collaborative approach to planning and implementing conservation programmes. [ABSTRACT FROM AUTHOR]

To assess the efficacy of topical ciplukan as an anti-inflammatory agent targeting the expression of IL-17 and IFN-γ.Methods: Psoriasis was induced using imiquimod cream, therefore divided into five groups. Group I, the psoriasis control group, received only imiquimod cream. Groups C1 and C2 received imiquimod cream followed by a mixture of Ciplukan and vaseline in a 1:2 and 1:4 ratio, respectively. Group M, the standard therapy group, received imiquimod cream, followed by mometasone furoate cream. Lastly, group V, the vehicle group, received imiquimod cream followed by vaseline album. Expression of IL-17 and IFN-γ in mice's skin tissue was analysed using reverse transcription polymerase chain reaction (RT-PCR) after seven days of treatment.Results: The mean expression of IL-17 in Group C1 (22.60) was significantly lower (p = 0.012) than in the psoriasis control group (23.60), and there was no significant difference (p = 0.613) in Group M (22.41). The mean expression of IFN-γ in Group C1 (26.97) and Group C2 (27.03) was also significantly lower (p = 0.026 and p = 0.026, respectively) than Group I (28.80), and there was no significant difference (p = 0.180 and p = 0.093, respectively) than Group M (26.03).Conclusion: Expression of IL-17 and IFN-γ in the ciplukan group is lower than in the psoriasis control group, and there is no significant difference compared to the standard therapy group. [ABSTRACT FROM AUTHOR]

The Sunda clouded leopard (Neofelis diardi Cuvier, 1823) is the largest predator and the keystone species on Borneo Island. Therefore, the existence of N. diardi is very important to maintain the stability and healthy of ecosystems in Kalimantan Forest. Sebangau National Park (SNP), Central Kalimantan Province is one of the important habitats for this species because it is formed by peat swamp ecosystem and it has function to maintain the balance of the global climate. Data of the distribution factors of N. diardi were expected to used for monitoring and inventorying of population this species, especially in SNP. Data collection was conducted from June until November 2014 through methods of 12 track-sets; 9 units camera traps; and signs of animal presence likely footprints, feces, claws, scratches, scrapes, and vocalizations in 2 grids, each size 6 x 6 km2. This study results show that the distribution of N. diardi is affected by five factors namely, the distance from water source (P = 0,002); the distance from the potential of disturbance (P = 0,017); forest canopy density (P= 0,04); peat depth (P = 0,002); and habitat types in the SNP (P = 0,011). Only the altitude factor does not affect the distribution of N. diardi (P = 0,064) at SNP. Furthermore, this study also indicates that the presence and abundance of animal preys as another factor affecting the distribution of N. diardi at SNP. This condition is caused by the tendency of N. diardi encounter in a RAI values of animal preys on medium-grade (9,38; 10,53) and high (14,52; 18,60; 18,60). Finally, this study also demonstrates that the existence of N. diardi can be considered as an indicator species for forest in good condition. [ABSTRACT FROM AUTHOR]

In the present paper, we consider the non-smooth atomic decomposition of generalized Orlicz-Morrey spaces. The result will be sharper than the existing results. As an application, we consider the boundedness of the bilinear operator, which is called the Olsen inequality nowadays. To obtain a sharp norm estimate, we first investigate their predual space, which is even new, and we make full advantage of the vector-valued inequality for the Hardy-Littlewood maximal operator. [ABSTRACT FROM AUTHOR]

We revisit the space lp of p-summable sequences of real numbers. In particular, we show that this space is actually contained in a (weighted) inner product space. The relationship between lp and the (weighted) inner product space that contains lp is studied. For p > 2 we also obtain a result which describe how the weighted inner product space is associated to the weights. [ABSTRACT FROM AUTHOR]

Anogenital warts (AGW) are among the most common sexually transmitted infections worldwide. The condition may be persistent, increase in size and number, and have a high recurrence rate. There are many therapeutic options of AGW, but none of them prevented recurrence, only yielded partial responses and have the propensity to cause scars. Immunotherapy by purified protein derivative (PPD) is one of the therapeutic options for AGW, which effectively reduces the number of lesions until complete clearance, with minimal side effects and less recurrence rate. This case report aims to demonstrate the effectiveness, safety, and low recurrence rate of intralesional PPD injection as an alternative therapy for AGW. We reported one case of AGW in an immunocompetent 30-year-old homosexual man who was given 3 doses of 0.2 mL PPD injected intralesionally. As a result, clinical improvement was observed starting from the 18th day, with some of the lesions decreasing in size, and on the 46th day, all of the lesions disappeared. There was no significant side effect. Within two years of follow-up, no recurrence was observed. Intralesional injection of PPD can stimulate the immune response against human papillomavirus (HPV) infection both on the injection site and distant from the injection site. Previous studies have shown promising results of intralesional PPD, with low recurrence in over six-month follow-up and no side effects. Intralesional injection of PPD can be considered as an alternative therapy due to its minimal side effects and its long-term low recurrence rate. [ABSTRACT FROM AUTHOR]