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Ti 2 AlNb-based intermetallic alloys are considered to be one of the excellent potential materials applied in engineering practice. Selective laser melting (SLM) is a promising technology for manufacturing of parts with a combination of complex design and high mechanical properties. The possibility of in-situ synthesis of Ti-22Al-25Nb and Ti-5Al alloys using elemental powder mixtures has been demonstrated in this paper. The bulk samples were produced using 275 W and 950 W laser power. The microstructure, phase composition, microhardness of the produced material have been studied in this work, as well as the effect of heat treatment by means of homogenizing annealing and subsequent aging on the microstructure and chemical homogeneity of the material. It has been shown that Ti-22Al-25Nb material, produced by SLM, after annealing consists of B2-grains with Ti 2 AlNb and Ti 3 Al precipitates with homogeneous distribution of the elements in the bulk material. [ABSTRACT FROM AUTHOR]

This article takes an approach to creating a machine learning model for the oil and gas industry. This task is dedicated to the most up-to-date issues of machine learning and artificial intelligence. One of the goals of this research was to build a model to predict the possible risks arising in the process of drilling wells. Drilling of wells for oil and gas production is a highly complex and expensive part of reservoir development. Thus, together with injury prevention, there is a goal to save cost expenditures on downtime and repair of drilling equipment. Nowadays, companies have begun to look for ways to improve the efficiency of drilling and minimize non-production time with the help of new technologies. To support decisions in a narrow time frame, it is valuable to have an early warning system. Such a decision support system will help an engineer to intervene in the drilling process and prevent high expenses of unproductive time and equipment repair due to a problem. This work describes a comparison of machine learning algorithms for anomaly detection during well drilling. In particular, machine learning algorithms will make it possible to make decisions when determining the geometry of the grid of wells—the nature of the relative position of production and injection wells at the production facility. Development systems are most often subdivided into the following: placement of wells along a symmetric grid, and placement of wells along a non-symmetric grid (mainly in rows). The tested models classify drilling problems based on historical data from previously drilled wells. To validate anomaly detection algorithms, we used historical logs of drilling problems for 67 wells at a large brownfield in Siberia, Russia. Wells with problems were selected and analyzed. It should be noted that out of the 67 wells, 20 wells were drilled without expenses for unproductive time. The experiential results illustrate that a model based on gradient boosting can classify the complications in the drilling process better than other models. [ABSTRACT FROM AUTHOR]

Aims. The aim of this work is to show that the seasonal changes and vertical distribution profiles of hydrogen chloride (HCl) on Mars, as observed by the ExoMars Trace Gas Orbiter, are consistent with the production of gas-phase chlorine atoms from airborne dust and a subsequent rapid uptake of HCl onto water ice particles. Methods. A 1D photochemistry model was equipped with a chlorine reaction network and driven by dust, water ice, and water vapour profiles measured by the ExoMars Trace Gas Orbiter instrumentation in Mars year 34. The release of Cl and O atoms from airborne dust via the hydration and photolysis of perchlorate within dust grains was parameterised using prior laboratory studies, and the heterogeneous uptake of chlorine species onto dust and water ice was included for processes known to occur in Earth's atmosphere. Results. Observed seasonal variations in Martian HCl are reproduced by the model, which yielded low HCl abundances (<1 ppbv) prior to the dust season that rise to 2–6 ppbv in southern latitudes during the dust season. Structured atmospheric layers that coincide with locations where water ice is absent are also produced. As a consequence of the Cl atoms released via our proposed mechanism, the atmospheric lifetime of methane is shortened by two orders of magnitude. This suggests that the production of Cl induced by the breakdown of hydrated perchlorate via UV radiation (or another electromagnetic radiation) in airborne Martian dust, consistent with observed profiles of HCl, could help reconcile reported variations in methane with photochemical models. [ABSTRACT FROM AUTHOR]

The umbilical cord is a material that enhances regeneration and is devoid of age-related changes in the extracellular matrix (ECM). The aim of this work was to develop a biodegradable scaffold from a decellularized human umbilical cord (UC-scaffold) to heal full-thickness wounds. Decellularization was performed with 0.05% sodium dodecyl sulfate solution. The UC-scaffold was studied using morphological analysis methods. The composition of the UC-scaffold was studied using immunoblotting and Fourier transform infrared spectroscopy. The adhesion and proliferation of mesenchymal stromal cells were investigated using the LIVE/DEAD assay. The local reaction was determined by subcutaneous implantation in mice (n = 60). A model of a full-thickness skin wound in mice (n = 64) was used to assess the biological activity of the UC-scaffold. The proposed decellularization method showed its effectiveness in the umbilical cord, as it removed cells and retained a porous structure, type I and type IV collagen, TGF-β3, VEGF, and fibronectin in the ECM. The biodegradation of the UC-scaffold in the presence of collagenase, its stability during incubation in hyaluronidase solution, and its ability to swell by 1617 ± 120% were demonstrated. Subcutaneous scaffold implantation in mice showed gradual resorption of the product in vivo without the formation of a dense connective tissue capsule. Epithelialization of the wound occurred completely in contrast to the controls. All of these data suggest a potential for the use of the UC-scaffold. [ABSTRACT FROM AUTHOR]

Articular cartilage damage still remains a major problem in orthopedical surgery. The development of tissue engineering techniques such as autologous chondrocyte implantation is a promising way to improve clinical outcomes. On the other hand, the clinical application of autologous chondrocytes has considerable limitations. Mesenchymal stromal cells (MSCs) from various tissues have been shown to possess chondrogenic differentiation potential, although to different degrees. In the present study, we assessed the alterations in chondrogenesis-related gene transcription rates and extracellular matrix deposition levels before and after the chondrogenic differentiation of MSCs in a 3D spheroid culture. MSCs were obtained from three different tissues: umbilical cord Wharton's jelly (WJMSC—Wharton's jelly mesenchymal stromal cells), adipose tissue (ATMSC—adipose tissue mesenchymal stromal cells), and the dental pulp of deciduous teeth (SHEDs—stem cells from human exfoliated deciduous teeth). Monolayer MSC cultures served as baseline controls. Newly formed 3D spheroids composed of MSCs previously grown in 2D cultures were precultured for 2 days in growth medium, and then, chondrogenic differentiation was induced by maintaining them in the TGF-β1-containing medium for 21 days. Among the MSC types studied, WJMSCs showed the most similarities with primary chondrocytes in terms of the upregulation of cartilage-specific gene expression. Interestingly, such upregulation occurred to some extent in all 3D spheroids, even prior to the addition of TGF-β1. These results confirm that the potential of Wharton's jelly is on par with adipose tissue as a valuable cell source for cartilage engineering applications as well as for the treatment of osteoarthritis. The 3D spheroid environment on its own acts as a trigger for the chondrogenic differentiation of MSCs. [ABSTRACT FROM AUTHOR]

Thermal tides in the Martian atmosphere are analyzed using temperature profiles retrieved from nadir observations obtained by the TIRVIM Fourier‐spectrometer, part of the Atmospheric Chemistry Suite onboard the ExoMars Trace Gas Orbiter. The data is selected near the northern summer solstice at solar longitude (LS) 75°–105° of Martian Year 35. The observations have a full local time coverage, which enables analyses of daily temperature anomalies. The observed zonal mean temperature is lower by 4–6 K at ∼100 Pa, but higher toward the summer pole, compared to the Laboratoire de Météorologie Dynamique (LMD) Mars General Circulation Model (GCM). Wave mode decomposition shows dominant diurnal tide and important semi‐diurnal tide and diurnal Kelvin wave, with maximal amplitudes of 5, 3, and 2.5 K, respectively, from tens to hundreds of Pa. The results generally agree well with the LMD Mars GCM, but with noticeable earlier phases of diurnal (∼1 hr) and semi‐diurnal (∼3 hr) tides. Plain Language Summary: Unlike the Earth, daily temperature variation on Mars is as large as tens of degrees because of its thin atmosphere. The sunlight absorbed by the Martian surface and dust in the atmosphere leads to dramatic temperature increase in the lower atmosphere during daytime. Such large and regular changes can trigger temperature waves, and some modes of them can propagate into higher altitudes, where they become the major factor controlling the daily temperature variation. In this work, temperature profiles obtained using thermal‐infrared spectra are analyzed. Zonal mean temperature is compared with numerical simulations of the Martian atmosphere. Different types of the wave modes are computed through decomposition. Results from the observation agree well with model prediction when the observation mechanisms are taken into consideration. Estimation of the strength of these waves can be improved in the future with improved design of observation strategies. Key Points: Thermal tides in the Martian atmosphere are investigated using temperature profiles retrieved from TIRVIM nadir observationsDiurnal tide dominates daily temperature variations; semi‐diurnal tide and diurnal Kelvin wave are also importantObservations agree well with numerical simulations, but suggest phases of diurnal and semi‐diurnal tides earlier than predicted [ABSTRACT FROM AUTHOR]

Background: Urinary tract infections (UTIs) are common in women, and during pregnancy can cause significant morbidity. Growing and greatly varying antimicrobial resistance (AMR) of Enterobacteriaceae, responsible for most UTIs, necessitates regular local AMR surveillance. In obstetric population, where beta-lactams are the mainstay for treatment of severe UTIs, particular focus should be placed on beta-lactam resistance. This study aimed to evaluate AMR rates and frequency of extended spectrum beta-lactamase (ESBL) and carbapenemase genes in uropathogenic Enterobacteriaceae among reproductive-age women in St. Petersburg, Russia.Materials/methods: Urine samples were collected from consecutive reproductive-age women, who attended the D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology from October 2017 to November 2019, and cultured according to routine procedures. Susceptibility to antibiotics and ESBL production was determined using the disc diffusion method according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines. All urine samples and Enterobacteriaceae isolates were tested for ESBL and carbapenemase genes using real-time PCR.Results: Enterobacteriaceae were detected in 91 (56 pregnant and 35 non-pregnant) of 119 (76%) included women. The vast majority of Enterobacteriaceae strains were susceptible to nitrofurantoin, fosfomycin and meropenem (99-100%). The frequency of strains susceptible to penicillins and cephalosporins ranged from 59% to 82%; 78% of strains were susceptible to ciprofloxacin. ESBL production was phenotypically detected in 15 (16%) Enterobacteriaceae strains, with CTX-M genes revealed in all cases. In all corresponding urine samples, CTX-M genes were also detected. The remaining 104 urine samples were negative for CTX-M genes. In none of the isolates and urine samples, carbapenemase genes were present.Conclusions: The frequency of ESBL producing Enterobacteriaceae was relatively high (16%), with CTX-M genes detected in all cases in both urine and urine cultures. Rapid PCR detection of CTX-M genes directly in urine samples from women with pyelonephritis can be valuable for timely informing treatment choices. [ABSTRACT FROM AUTHOR]

Evaluation of circulating group B streptococcus (GBS) strains is important to assess the potential effects of GBS prevention strategies in a certain region. This study aimed at estimating the distributions of capsular polysaccharide (CPS) types and pilus profiles, and the rates of antimicrobial resistance among GBS strains isolated from colonized pregnant women and newborns in 2010–2011 and 2017–2018 in St. Petersburg, Russia. A total of 261 GBS isolates have been investigated. Antibiotic susceptibility testing was performed using the disc-diffusion method. CPS types and pilus profiles were determined by using PCR. Over the 9-year period, the resistance of GBS to both erythromycin and clindamycin has significantly increased, exceeding 30% in 2017–2018. The most prevalent CPS types were Ia, III, and V. Significant shifts were observed in the frequency of CPS types III (decreased) and V (increased), which resulted in a significant reduction (from 77 to 63%) in the potential coverage by a trivalent vaccine (including serotypes Ia, Ib, and III), whereas that of a pentavalent vaccine (including serotypes Ia, Ib, II, III, and V) remained largely unchanged (approximately 95%). The most common pilus profiles were PI-1/2a, PI-2a, and PI-1a/2b, and pilus genotype distribution has not changed with time. High and steadily growing resistance of perinatal GBS strains to clindamycin requires restricting its use to penicillin-allergic women at high risk for anaphylaxis and testing the GBS strains for their susceptibility to this antibiotic. A pentavalent CPS-based vaccine covers the vast majority of perinatal GBS strains in Russia. [ABSTRACT FROM AUTHOR]

The loss of water from Mars to space is thought to result from the transport of water to the upper atmosphere, where it is dissociated to hydrogen and escapes the planet. Recent observations have suggested large, rapid seasonal intrusions of water into the upper atmosphere, boosting the hydrogen abundance. We use the Atmospheric Chemistry Suite on the ExoMars Trace Gas Orbiter to characterize the water distribution by altitude. Water profiles during the 2018–2019 southern spring and summer stormy seasons show that high-altitude water is preferentially supplied close to perihelion, and supersaturation occurs even when clouds are present. This implies that the potential for water to escape from Mars is higher than previously thought. [ABSTRACT FROM AUTHOR]

The aim of the paper is to provide an analysis of news and financial data using their network representation. The formation of network structures from data sources is carried out using two different approaches: by building the so-called market graph in which nodes represent financial assets (e.g., stocks) and the edges between nodes stand for the correlation between the corresponding assets, by constructing a company co-mention network in which any two companies are connected by an edge if a news item mentioning both companies has been published in a certain period of time. Topological changes of the networks over the period 2005-2010 are investigated using the sliding window of six-month duration. We study the stability of the market graph and the company co-mention network over time and establish which of the two networks was more stable during the period. In addition, we examine the impact of the crisis of 2008 on the stability of the market graph as well as the company co-mention network. The networks that are considered in this paper and that are the objects of our study (the market graph and the company co-mention network) have a non-changing set of nodes (companies), and can change over time by adding/removing links between these nodes. Different graph similarity measures are used to evaluate these changes. If a network is stable over time, a measure of similarity between two graphs constructed for two different time windows should be close to zero. If there was a sharp change between the graphs constructed for two adjacent periods, then this should lead to a sharp increase in the value of the similarity measure between these two graphs. This paper uses the graph similarity measures which were proposed relatively recently. In addition, to estimate how the networks evolve over time we exploit QAP (Quadratic Assignment Procedure). While there is a sufficient amount of works studying the dynamics of graphs (including the use of graph similarity metrics), in this paper the company co-mention network dynamics is examined both individually and in comparison with the dynamics of market graphs for the first time. [ABSTRACT FROM AUTHOR]

A study has been undertaken to verify the feasibility of using powder-bed fusion additive manufacturing to fabricate Ti-5Al, Ti-6Al-7Nb, and Ti-22Al-25Nb alloys from elemental powders. Selective Laser Melting was used to produce bulk samples from mechanical mixtures of elemental powders for Ti-5Al, Ti-6Al-7Nb, and Ti-22Al-25Nb alloys. For Ti-Al-Nb system, annealing was carried out at 1050–1350 °C for 1–3,5 h followed by furnace cooling. The systematic characterization of the samples was done using scanning electron microscopy (SEM), optical microscopy (OM), X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDX), and tensile testing. It was shown that using elemental powders it is possible to synthesize titanium alloys by Selective Laser Melting. In case of Ti-5Al, powder-bed fusion of powders resulted in a homogeneous microstructure, while for Ti-6Al-7Nb and Ti-22Al-25Nb a subsequent heat treatment at 1350 °C temperature is required to fully dissolve niobium particles. [ABSTRACT FROM AUTHOR]

Mesenchymal stromal cells (MSCs) have shown a high potential for cartilage repair. Collagen-based scaffolds are used to deliver and retain cells at the site of cartilage damage. The aim of the work was a comparative analysis of the capacity of the MSCs from human adipose tissue to differentiate into chondrocytes in vitro and to stimulate the regeneration of articular cartilage in an experimental model of rabbit knee osteoarthrosis when cultured on microheterogenic collagen-based hydrogel (MCH) and the microparticles of decellularized porcine articular cartilage (DPC). The morphology of samples was evaluated using scanning electron microscopy and histological staining methods. On the surface of the DPC, the cells were distributed more uniformly than on the MCH surface. On day 28, the cells cultured on the DPC produced glycosaminoglycans more intensely compared to the MCH with the synthesis of collagen type II. However, in the experimental model of osteoarthrosis, the stimulation of the cartilage regeneration was more effective when the MSCs were administered to the MCH carrier. The present study demonstrates the way to regulate the action of the MSCs in the area of cartilage regeneration: the MCH is more conducive to stimulating cartilage repair by the MSCs, while the DPC is an inducer for a formation of a cartilage-like tissue by the MSCs in vitro. [ABSTRACT FROM AUTHOR]

The ExoMars Trace Gas Orbiter began science operations in April 2018. We report on dataprocessing and analysis for the Atmospheric Chemistry Suite mid-infrared channel(ACSMIR) for the first year of operations. ACS MIR is a cross-dispersion spectrometer operatingin solar occultation mode. Level 0 data (raw detector images) are processed at the SpaceResearch Institute in Moscow (IKI) and spectral and wavenumber calibration areperformed at LATMOS in Paris to produce a level 1 data product of transmissionspectra. Trace gas retrievals are performed at LATMOS with the JPL Gas Fittingsoftware (GFIT). We present retrievals of volume mixing ratio (VMR) verticalprofiles of major gas species (CO, H2O, HDO) and the current state of our searchfor undetected gases (e.g., hydrocarbons, sulphur and chlorine bearing species).Preliminary results show a dependence on latitude for CO above 50 km, a correlationbetween water vapour content and dust loading, and low upper limits for CH4. [ABSTRACT FROM AUTHOR]

The ExoMars Trace Gas Orbiter (TGO), a mission by ESA and Roscosmos, was launched inMarch 2016 and reached its final, near-circular 400 km orbit around Mars in March, 2018. Onboard TGO, the Atmospheric Chemistry Suite (ACS) is a set of three spectrometers includinga thermal-infrared channel, TIRVIM. This Fourier-transform spectrometer covers the range600–6000 cm−1 (1.7–17μm) with a spectral resolution of 1.2 cm−1. We focus here on nadirobservations in the range 600-1300 cm−1, which covers absorption by CO2 (centered at 667cm−1), water ice clouds (centered at 820 cm−1) and dust (centered at 1100 cm−1).The advantage of the TIRVIM data set over previous instruments comes from theTGO orbit, which is not sun-synchronous and was designed to sample a completedaily cycle every 55 days. Hence, TIRVIM has the capacity to uniquely study boththe diurnal and seasonal variability of the thermal structure, dust and ice cloudopacity. We have developed a radiative transfer model coupled to a retrieval algorithm thatexploits TIRVIM spectra to simultaneously retrieve vertical profiles of the temperature from 5 to 45 km, surface temperature, and integrated optical depth of dust and water ice clouds.This algorithm was tested and validated against synthetic observations generated undervarious conditions (local time, seasons, latitude, aerosol load,...). We have thenapplied this algorithm to the first 45 days of TIRVIM data acquired in March-April,2018. The retrieved temperature profiles have been validated against thousandsof co-located measurements acquired by the Mars Climate Sounder around 3amand 3pm, a limb-viewing radiometer onboard Mars Reconnaissance Orbiter. Theagreement between the two data sets is very satisfactory. In particular, the amplitudeof the diurnal thermal tide as seen by MCS is very well captured by TIRVIM atpressures greater than 10 Pa. However, TIRVIM underestimates it in the range 1–10 Pa,which is due to a much poorer vertical resolution in this region (as expected froma nadir-viewing sounder). We will present these results with an emphasis on thediurnal cycle of the atmospheric temperature and the aerosols load, along withcomparisons with predictions from the LMD Mars GCM. Analysis of TIRVIM dataacquired during the dust storm in June-July 2018 is in progress and will also bepresented. Acknowledgements: The ACS experiment is led by IKI in Moscow. We acknowledgesupport by CNES and Roscosmos. [ABSTRACT FROM AUTHOR]

The ExoMars Trace Gas Orbiter (TGO) is a joint ESA-Roscosmos mission to Mars that has been launched in March 2016. The aerobreaking phase has ended in February 2018 followed by the start of nominal scientific work on the near-circular 400 km orbit in April 2018. The Atmospheric Chemistry Suite (ACS) is a set of three spectrometers (NIR, MIR, and TIRVIM), capable to observe Mars atmosphere in solar occultations, nadir and limb geometry. TIRVIM instrument is a Fourier-spectrometer operating in the 1.7−17 µm spectral range. NIR instrument is a near-infrared spectrometer covering the 0.7-1.6 µm spectral range with a resolving power of ≥20,000. Both spectrometers are operated in solar occultation and nadir modes.The main fraction of aerosols on Mars consists of mineral dust, while H2O ice and CO2 ice crystals are also encountered depending on the season and location. Combination of TIRVIM and NIR spectra obtained in solar occultation mode permits spectral separation of dust and H2O ice clouds particles and retrieval of vertical distribution of aerosols. In this work, we will report analysis of aerosol properties during 2018 dust storm.AcknowledgementsExoMars is the space mission of ESA and Roscosmos. The ACS experiment is led by IKI Space Research Institute in Moscow. The project acknowledges funding by Roscosmos and CNES. Science operations of ACS are funded by Roscosmos and ESA. M. Luginin acknowledges the support from the Ministry of Science and Higher Education of the Russian Federation, grant №14.W03.31.0017. [ABSTRACT FROM AUTHOR]

The Atmospheric Chemistry Suite (ACS) on board ESA-Roscosmos ExoMars 2016 TraceGas Orbiter (TGO) spacecraft will complete one year of Mars observations in March 2019.ACS consists of three infrared spectrometers targeting the detection of trace gases of potentialgeophysical or biological interest, as well as the monitoring of the martian atmosphere state.ACS channels feature high resolving power (&#x003E;10,000) and broad spectral coverage (0.7 to17 μm). The near-infrared (NIR) channel covers the 0.7-1.6 μm spectral rangewith a resolving power of ≥20,000. Results of solar occultation sounding by NIR,including profiling of H2O with high accuracy and in a broad altitude range, and thefirst ever profiling molecular oxygen O2 in the lower atmosphere will be reported.The mid-infrared (MIR) channel is a high spectral resolution (resolving power of≥30,000) instrument dedicated to solar occultation measurements in the 2.2-4.4 μmrange. MIR is conceived to accomplish the most sensitive measurements of the tracegases in the Martian atmosphere, allowing also parallel profiling of the abundantcomponents such as CO2, H2O and their isotopologues. MIR results putting stringentupper limits to methane abundance will be reported. The thermal-infrared channel(TIRVIM) is a Fourier-transform spectrometer with cryogenically-cooled detectorencompassing the spectral range of 1.7-17 μm. Observing the CO2 15-μm band in nadirTIRVIM returns temperature profiles from the surface up to 50-60 km, together withthe dust and water ice optical depth. Also the surface temperature is measured.In solar occultation TIRVIM delivers profiles of CO2, CO, H2O and aerosols, aswell allowing to distinguish between mineral and condensate aerosols. ACS hasmonitored the state of the martian atmosphere before and during the dust event2018A. The status of the experiment and key findings will be summarized in the talk. [ABSTRACT FROM AUTHOR]

The ExoMars Trace Gas Orbiter (TGO), a collaborative project between the European Space Agency and Roscosmos, was successfully inserted into Mars orbit on 19 October 2016, and reached its final science orbit on 7 April 2018. TGO began taking observations as part of commissioning operations in March 2018.At the Laboratoire de Météorologie Dynamique (LMD) we are responsible for data assimilation of observations from the Atmospheric Chemistry Suite (ACS) thermal infrared instrument (TIRVIM) on board TGO. This instrument measures vertical profiles of temperature as well as dust and water ice integrated content, at various local times, latitudes and seasons.Here we report on assimilation of the first six weeks of TIRVIM observations into the LMD Mars General Circulation Model (GCM), using the Local Ensemble Transform Kalman Filter (LETKF) technique. The LETKF is an ensemble-based assimilation scheme where we typically use 16 ensemble members and multiplicative inflation to adjust the background ensemble error covariance. The assimilation focuses on atmospheric temperatures retrieved from nadir thermal emission spectra taken between 2018 March 13 and 2018 April 28. These have been calibrated and then retrieved using a line-by-line radiative transfer model. The observations cover various local times of day with full coverage in longitude every 7-10 days, over +/- 75 degree latitude, with vertical coverage between 5-45 km altitude.We shall report on the differences between the assimilation and a free-running model, particularly at local times of day that have not been observed prior to TGO. We shall also report on progress combining assimilation of ACS observations with profiles from Mars Climate Sounder on board NASA's Mars Reconnaissance Orbiter, to fill in anticipated gaps in the ACS observational record and to sample the local time of day more fully. [ABSTRACT FROM AUTHOR]

The ExoMars Trace Gas Orbiter (TGO), a mission by ESA and Roscosmos started its operational scientific phase in March 2018. The Atmospheric Chemistry Suite (ACS) is a set of three spectrometers (NIR, MIR, and TIRVIM) designed to observe the Martian atmosphere in solar occultation, nadir and limb geometry. The thermal infrared channel — TIRVIM is a Fourier-transform spectrometer covering the spectral range of 1.7–17 μm with a spectral resolution of 0.8 cm−1 for nadir observations. In nadir operation mode, the primary goal of TIRVIM is the long-term monitoring of atmospheric temperature and aerosol (dust and ice clouds) state from the surface up to approximately 60 km. In June 2018 a global dust storm enshrouded Mars for more than a month. We present the evolution of the thermal structure, dust content and optical properties during this period. AcknowledgementsExoMars is the space mission of ESA and Roscosmos. The ACS experiment is led by IKI Space Research Institute in Moscow. The project acknowledges funding by Roscosmos and CNES. Science operations of ACS are funded by Roscosmos and ESA. [ABSTRACT FROM AUTHOR]