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Chorioamniotic separation increases significantly the risk of preterm prelabor rupture of membranes and preterm delivery2-4; the concomitant presence of vasa previa increases the risk of severe and acute bleeding and fetal death. 3 Govaerts J, Cryns P, Jacquemyn Y. Spontaneous chorioamniotic membrane separation discovered by preterm prelabor rupture of membranes. Macroscopic evaluation of the placenta and membranes was consistent with velamentous cord insertion (Figure 2a) and showed multiple unprotected vessels coursing through the membranes (Figure 2b). [Extracted from the article]