1. Tumores neuroendocrinos del páncreas. Resultados quirúrgicos y sobrevida alejada.
- Author
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GALINDO R., JOSÉ, GABRIELLI N., MAURICIO, BARROS C., DIEGO, MOISAN P., FABRIZIO, MARTÍNEZ M., MÓNICA, TORRES M., JAVIERA, FLORES M., MACARENA, GUERRA C., JUAN FRANCISCO, MARTÍNEZ C., JORGE, and JARUFE C., NICOLÁS
- Subjects
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NEUROENDOCRINE tumors , *SURGICAL excision , *CASE studies , *BIOPSY , *MULTIPLE endocrine neoplasia - Abstract
Background: Pancreatic neuroendocrine tumors (PNET) account for 1-2% of pancreatic neoplasms. Its incidence has increased in recent years probably due to improved imaging studies. Aim: To analyze the clinical characteristics, surgical outcomes and overall survival of patients with PNET who underwent resective surgery. Methods: Case series study. Data was collected from the central database and clinical records from patients with biopsy-proven PNET's who underwent surgical resection from June 2005 to June 2012. Results: Twenty patients were included (10.6% of all pancreatic resections), 12 female, with a median age of 44 [20-77] years. Abdominal pain was the most common symptom. Two patients had a type 1 multiple endocrine neoplasia (MEN-1) syndrome. Pre-operative work up included CT, MR and/or PET/CT. Five patients had functional tumors. Five Whipple procedures, 14 distal pancreatectomies and 1 enucleation were performed. Among the postoperative complications, there were 5 type B and 1 type C pancreatic fistulas. There was no mortality. At 31 [5-90] month median follow-up, overall survival was 100%. Conclusion: PNETs represent an increasing reason for pancreatic resection in our center. Surgical resection of the tumor with negative microscopic margins is the treatment of choice. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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