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Pure molybdenum disulfide (MoS2) solid lubricant coatings could attain densities comparable to doped films (and the associated benefits to wear rate and environmental stability) through manipulation of the microstructure via deposition parameters. Unfortunately, pure films can exhibit highly variable microstructures and mechanical properties due to processes that are not controlled during deposition (i.e., batch-to-batch variation). This work focuses on developing a relationship between density, hardness, friction, and wear for pure sputtered MoS2 coatings. Results show that dense films (ρ = 4.5 g/cm3) exhibit a 100 × lower wear rate compared to porous coatings (ρ = 3.04–3.55 g/cm3). The tribological performance of high density pure MoS2 coatings is shown to surpass that of established composite coatings, achieving a wear rate 2 × (k = 5.74 × 10–8 mm3/Nm) lower than composite MoS2/Sb2O3/Au in inert environments. [ABSTRACT FROM AUTHOR]

Steady-state fluctuations in the friction force of molybdenum disulfide (MoS2), a prototypical lamellar solid, were analyzed experimentally for newton-scale forces and computationally via molecular dynamics simulations for nanonewton-scale forces. A mean field model links the statics and the dynamics of the friction behavior across these eight orders of magnitude in friction force and six orders of magnitude in friction force fluctuations (i.e., avalanches). Both the statistics and dynamics of the avalanches match model predictions, indicating that friction can be characterized as a series of avalanches with properties that are predictable over a wide range of scales. [ABSTRACT FROM AUTHOR]

Objective: To investigate prevalence and predictors of early depression response (EDR) in adolescents with substance use and depression receiving cognitive-behavioral therapy (CBT) for substance use and to test the efficacy of supplemental CBT targeting depression (CBT-D) for non-EDR adolescents in an adaptive treatment approach.Method: At 2 sites, 95 youths (ages 14-21, mean [SD] = 17.4 [1.8]) with alcohol or cannabis use and depressive symptoms received up to 12 sessions of CBT for substance use over 14 weeks. Assessments were at baseline and weeks 4, 9, and 14. The Children's Depression Rating Scale-Revised was the primary depression measure, with a reduction of 50% or more on this scale at week 4 defining EDR. The primary substance use outcomes of alcohol use, heavy alcohol use, and cannabis use frequency were assessed via interview report on the Alcohol Consumption Questionnaire and the Drug Checklist. Urinalysis provided a secondary measure of cannabis use. Non-EDR adolescents were randomly assigned to supplemental CBT-D or enhanced treatment as usual (ETAU).Results: Thirty-five adolescents (37%; 95% CI, 27%-47%) demonstrated EDR. Fewer days of cannabis use (odds ratio 0.977; 95% CI, 0.961-0.992) and absence of conduct disorder (odds ratio 0.149; 95% CI, 0.031-0.716) predicted EDR. Frequency of drinking (F1,82 = 11.09, η2 = 0.119, p = .001), heavy drinking (F1,82 = 19.91, η2 = 0.195, p < .0001), and cannabis use (F1,220 = 35.01, η2 = 0.137, p < .001) decreased over time for EDR, CBT-D, and ETAU adolescents, with EDR adolescents evidencing earlier lower cannabis use (F2,220 = 4.16, η2 = 0.036, p = .0169). Negative (clean) urine screens increased over time (F1,219 = 5.10, η2 = 0.023, p = .0249). Comparison of CBT-D and ETAU indicated that depression significantly decreased over time in both groups (F1,48 = 64.20, η2 = 0.572, p < .001), with no advantage for CBT-D.Conclusion: Approximately one-third of adolescents with substance use and depression attain EDR during substance use treatment. Less frequent cannabis use facilitates depression response. The relatively small sample may have precluded identification of additional EDR predictors.Clinical Trial Registration Information: Treatment for Teens With Alcohol Abuse and Depression; https://clinicaltrials.gov/; NCT02227589. [ABSTRACT FROM AUTHOR]

We report an investigation of the friction mechanisms of MoS2 thin films under changing environments and contact conditions using a variety of computational and experimental techniques. Molecular dynamics simulations were used to study the effects of water and molecular oxygen on friction and bonding of MoS2 lamellae during initial sliding. Characterization via photoelectron emission microscopy (PEEM) and Kelvin probe force microscopy (KPFM) were used to determine work function changes in shear modified material within the top few nanometers of MoS2 wear scars. The work function was shown to change with contact conditions and environment, and shown by density functional theory (DFT) calculations and literature reports to be correlated with lamellae size and thickness of the basally oriented surface layer. Results from nanoscale simulations and macroscale experiments suggest that the evolution of the friction behavior of MoS2 is linked primarily to the formation or inhibition of a basally oriented, molecularly thin surface film with long-range order. [ABSTRACT FROM AUTHOR]

Objective: This brief report reviews the literature on moderators of treatment for adolescent depression. Treatment moderators can help to guide the process of personalizing intervention to individual patient characteristics. Method: We conducted a systematic search in PsycInfo and PubMed. We also reviewed references of previous reviews and searched for moderator analyses conducted secondary to published efficacy studies. Results: We review 27 studies that address the following categories of moderators: demographics, severity indices, comorbidity, contextual factors, history of abuse or trauma, and cognition and coping. We found limited evidence that demographic, contextual, or cognitive variables consistently moderated treatment for adolescent depression. There was some indication of moderation by race/ethnicity, presence of some comorbid disorders, greater depression severity, and a history of trauma. Conclusion: Our review found inconsistent findings across studies, likely due to the strong impact of predictors relative to moderators and limited statistical power. More research using innovative statistical approaches is necessary before treatment tailoring can be an empirically-based process. [ABSTRACT FROM AUTHOR]

Each phase of the deployment cycle poses challenges to military parents and children, with the post-deployment family reintegration period requiring returning military parents to resume such roles as direct caretaking and child discipline. Although veterans often report concerns about this domain of reintegration, existing measures permit only limited assessment of their parenting experiences. The authors initiated development of a self-report checklist to improve such assessment through two pilot studies. In the first, they generated a 30-item checklist of positive and challenging veteran parenting experiences, by interviewing nine clinicians experienced in assessment or intervention with veterans. In the second, 20 male veterans (mean age = 40.5 years) rated each parenting item based on their experiences during post-deployment family reintegration. They also indicated whether they had experienced any of 11 possible personal problems during this period and completed a family functioning measure. Results indicated that checklist items were relevant for the returning parents, that positive parenting experiences were endorsed by a higher percentage of veterans than challenging experiences, and that challenging experiences were associated with several personal problems and poorer family functioning. Further psychometric testing with larger, more representative samples of male and female veterans is needed, to establish the validity and utility of the measure. [ABSTRACT FROM AUTHOR]

We demonstrate inverse Hall-Petch behavior (softening) in pure copper sliding contacts at cryogenic temperatures. By kinetically limiting grain growth, it is possible to generate a quasi-stable ultra-nanocrystalline surface layer with reduced strength. In situ electrical contact resistance measurements were used to determine grain size evolution at the interface, in agreement with reports of softening in highly nanotwinned copper. We also show evidence of a direct correlation between surface grain size and friction coefficient, validating a model linking friction in pure metals and the transition from dislocation mediated plasticity to grain boundary sliding. [ABSTRACT FROM AUTHOR]

Objective: The authors investigated binge drinking, alcohol expectancies, and risky and protective drinking behaviors in relation to disordered eating behaviors in male and female college students.Participants: The full sample consisted of 7,720 undergraduate students, 18 to 22 years of age. Drinking behaviors were analyzed in 4,592 recent drinkers.Methods: Participants anonymously completed a survey as part of a universal alcohol abuse prevention program between September 2007 and April 2008.Results: Co-occurring disordered eating behaviors and binge drinking characterized 17.1% of males and 19.0% of females. Rates of binge drinking were higher in those with disordered eating behaviors. Students with disordered eating behaviors also had more positive and negative alcohol expectancies and engaged in more risky and fewer protective drinking behaviors than their counterparts.Conclusions: Students with disordered eating behaviors have outcome expectancies and behavior patterns associated with problematic drinking. These findings may enhance prevention and intervention programs. [ABSTRACT FROM PUBLISHER]

The Board of Education Virtual Working Group on Restrictions Affecting Diversity Training has generated a thoughtful approach to the challenge of conscience clauses. In this commentary short-term and longer-term implications of their publications are considered, as these might affect training programs seeking to implement the Working Group tenets. Among the short-term issues that need to be addressed by faculty members in professional psychology training programs are (a) whether to focus broadly or more narrowly in policies and program statements, (b) how to define a minimal level of competence in students' ability to work with diverse clients, (c) how to provide effective supervision when conflicts arise between a trainee's values and clinical needs of diverse clients, and (d) how to disclose policy in a manner likely to be understood by program applicants. Among the longer-term implications of the Working Groups statements are (a) how to reach a deeper understanding of what is meant by diversity in clinical training, (b) how to integrate the focus on differences with a developing appreciation of common humanity, (c) how to base diversity training and practice on psychological science, and (d) how to reduce judgmental thinking while facilitating the growth of clinical judgment. [ABSTRACT FROM AUTHOR]

This study examined the relative influence of peer socialization and selection on alcohol and marijuana use among 106 adolescents who received a brief intervention. Adolescents were recruited between 2003 and 2007 and followed for 12 months as part of a SAMHSA-funded study. Cross-lagged panel models using four assessment points examined the longitudinal relationship between adolescent substance use and peer substance involvement separately for alcohol and marijuana. Consistent with community studies, there was evidence of both peer socialization and peer selection for alcohol use, and only evidence of peer selection for marijuana use. Implications for research and intervention are discussed. [ABSTRACT FROM AUTHOR]

Abstract: Background: Most research on women veterans' mental health has focused on postraumatic stress disorder (PTSD) or reactions to military sexual trauma. Although depression is also a frequent diagnosis among women veterans, little is known about its characteristics, including comorbid conditions and patterns of disorder onset. We investigated lifetime diagnoses of major depressive disorder (MDD) and comorbid conditions in a primarily treatment-seeking research sample of male and female veterans to determine frequency of lifetime MDD, comorbid disorders and their temporal onset. Method: The 1700 veterans (346 women; 1354 men) completed diagnostic interviews as participants in a research registry. Rates of and gender differences in lifetime MDD and comorbid conditions (PTSD, other anxiety disorders, substance use and eating disorders) were calculated. We assessed the percentage of cases in which MDD preceded the comorbid condition (primary onset MDD). Results: Lifetime MDD was frequent in this sample, and significantly more common in women (46.5%) than in men (36.3%). Gender differences in comorbidity were found for anxiety and eating disorders (more common in women); and for alcohol and nicotine use disorders (more common in men). However, primary onset MDD was no more common among women than among men, and was in neither case the predominant pattern of comorbid lifetime disorder onset. Limitations: The sample is not representative of all veterans, and lifetime diagnoses were based on retrospective recall. Conclusions: MDD usually follows the onset of other comorbid disorders among women veterans, indicating the need to assess for earlier lifetime disorders in veterans with MDD. [Copyright &y& Elsevier]

Abstract: This study aimed to identify factors influencing trajectories of change in two outcome domains, frequency of substance use and quality of life (QOL), among adolescents receiving a brief evidence-based intervention. Participants were 106 adolescents, aged 13 to 21 years, who met criteria for a substance use disorder. The adolescents received a five-session intervention and completed four assessments over 12 months. Based upon a theoretical and empirical review, five putative predictors were tested: gender, age, severity of conduct disorder, severity of depression, and peer substance involvement. Results of a parallel-process latent growth curve model indicated that higher peer substance involvement and conduct severity predicted higher frequency of use at baseline, whereas higher peer substance involvement and depression severity predicted poorer QOL at baseline. Counter to predictions, higher depression severity predicted greater improvements in QOL following substance use treatment. The implications of baseline risk factors on adolescents'' response to intervention are discussed. [Copyright &y& Elsevier]

This study examines ethnic/racial differences at the start of treatment among participants in the Treatment for Adolescents with Depression Study (TADS). African American and Latino youth were compared to Caucasian youth on symptom presentation and cognitive variables associated with depression. Contrary to hypothesis, there were no significant differences in symptom presentation as measured by the interview-based items of the Children's Depression Rating Scale – Revised (CDRS-R). However, African American and Latino youth were both rated as demonstrating more severe symptoms on the observational items of the CDRS-R compared to Caucasian youth. In terms of cognitive variables associated with depression, African Americans reported fewer negative cognitive biases compared to Caucasians, but cognitive biases were significantly correlated with depression severity across ethnic groups. [ABSTRACT FROM AUTHOR]

Beutler’s call for an expanded psychotherapy agenda is appropriate but does not require downgrading the role of randomized clinical trials (RCTs). Large-scale RCTs are necessary to address questions of general public health importance. Within RCTs, psychotherapy can be conducted in a flexible, creative manner, similar to the practice of good clinicians. The aspirin analogy drawn from Klerman is not illustrative of how psychotherapy is actually conducted in contemporary clinical trials. A better analogy is that of music, which not only involves known ingredients and trainable, replicable skills, but also permits tailoring and improvisation. By conducting large RCTs, secondary analyses of these studies, and smaller controlled trials, psychotherapy researchers can address many clinically relevant questions. [ABSTRACT FROM AUTHOR]

Previous reviews of outpatient interventions for adolescent substance abuse have been limited in the extent to which they considered the methodological quality of individual studies. The authors assessed 31 randomized trials of outpatient interventions for adolescent substance abuse on 14 attributes of trial quality. A quality of evidence score was calculated for each study and used to compare the evidence in support of different outpatient interventions. Across studies, frequently reported methodological attributes included presence of an active comparison condition, reporting of baseline data, use of treatment manuals, and verification of self-reported outcomes. Infrequently reported attributes included power and determination of sample size, techniques to randomize participants to condition, specification of hypotheses and primary outcomes, use of treatment adherence ratings, blind assessment, and inclusion of dropouts in the analysis. Treatment models with evidence of immediate superiority in 2 or more methodologically stronger studies included ecological family therapy, brief motivational interventions, and cognitive-behavioral therapy. [ABSTRACT FROM AUTHOR]

Objectives: To develop a cognitive-behavioral treatment for depressed, substance-abusing adolescents, determine its feasibility, and test its association with symptomatic improvement. Method: Based on the efficacy of cognitive-behavioral interventions for either adolescent depression or substance abuse, an integrated group and family therapy intervention was developed for adolescents with both problems. The developers treated a group of six adolescents and families, and then trained experienced therapists to deliver the treatment to a second group of seven. Adolescents were 14 to 18 years of age. Measures of depression and substance abuse were collected before, during, and after treatment. Results: High retention in treatment and attendance at sessions supported feasibility. Parent interviews demonstrated significant improvement in adolescent substance abuse, and adolescent measures demonstrated significant improvement in both domains. Conclusions: Integrated outpatient cognitive-behavioral intervention is feasible and associated with improvement for depressed, substance-abusing adolescents. Controlled efficacy studies are needed. Additional treatment modalities will be required for a proportion of these adolescents. [ABSTRACT FROM AUTHOR]

Examined the relations among perceived racism and externalizing symptoms, internalizing symptoms, hopelessness, and self-concept in African American boys (N = 84). The experience of racism is a complex phenomenon that has been found to have negative psychological outcomes in adult studies of African Americans. There has been a gap in the empirical literature regarding the possible associations between perceived racism and children's psychological well-being. This study is an attempt to address that gap. Results demonstrated that experiences of racism were related to self- and parent-reported externalizing symptoms. Personal experiences of racism were related to self-reported internalizing symptoms, lower self-concept, and higher levels of hopelessness. Potential mediators (e.g., trait anger, hostile attribution bias) were analyzed. Additional analyses indicated that trait anger mediated a number of the observed relations between perceived racism and behavioral symptoms. The resuits of the study suggest that perceived racism is associated with multiple negative correlates for African American boys. [ABSTRACT FROM AUTHOR]

Tested the validity of the Devereux Scales of Mental Disorders (DSMD; Naglieri, LeBuffe, & Pfeiffer, 1994) in a sample of 108 adolescent psychiatric inpatients. DSMD scales were compared to parent-report, interview-based, self-report and diagnostic measures. DSMD measures of conduct problems and delinquency were significantly associated with the predicted parent-report, interview-based, and diagnostic measures of conduct disorder and substance abuse and not with any measures of anxiety or depression. DSMD measures of anxiety and depression were related to other parent-report ratings of internalizing symptoms but had more limited convergent and discriminant validity. The DSMD was compared to the Child Behavior Checklist (CBCL; Achenbach, 1991) for diagnostic classification accuracy. The two measures were comparable in classifying oppositional or conduct disorder. The CBCL was superior for classification of major depression. The DSMD was superior for classification of substance abuse. [ABSTRACT FROM AUTHOR]

The article cites a study which evaluated the clinical utility and construct validity of seven new MCBC behavior profiles. The relationship between the seven new behavior profiles and the clinical findings and recommendations that stem from an interdisciplinary evaluation of children referred to a clinic for development disabilities was determined. There were few differences in MCBC scale means and percentage occurrences of behavior profiles as a function of demographic factors and broad diagnostic categories such as mental retardation or learning disabilities.

The article focuses on a study which provides evidence with regard to the construct validity of the Missouri Children's Behavior Checklist (MCBC) by determining the relationship between the parents' MCBC ratings and the clinical findings and recommendations. The database for this study was obtained from clinical records of children seen in the Duke Developmental Evaluation Center. A sample of 301 children during 1977-1980 was collected. The MCBC was completed by parents of these children at the time of the intake interview. There were a few significant differences in scale means as a function of the demographic factors of sex, race, and socioeconomic status (SES) and there were no significant differences in percentage occurrences of any of the behavior profiles as a function of sex, race, or SES. With few significant differences in MCBC scales and profiles as a function of demographic factors, the relationship between the MCBC and behavior problems was relatively strong. The author also discuses the absence of a significant difference on the somatization scale. The findings indicate that ratings on this scale are not reflecting problems of a truly physical nature and supports the construct validity of the somatization scale as reflective of psychological concerns.

Assesses the diagnostic use of the symptom checklist to measure psychological distress in a sample of teenage patients. Measurement of depression and paranoid ideation by the discriminant validity; Correlation ofthe results to the dimensions of adolescent psychopathology; Potential of the checklist for use in the diagnosis of mental disorders.

The clinical question--"Which treatment(s) for which patients with what set of subgrouping characteristics working by what mechanism(s)?"--rests at the heart of differential therapeutics. Experimentally, this question reduces to a test of how well we can predict the outcome of treatment using the treatment conditions plus other moderating and mediating variables. Reflecting the discussions held at a recent National Institute of Mental Health (NIMH) conference on psychosocial treatments, and using pediatric anxiety disorders as a case in point, we discuss the problem of prediction in treatment outcome studies from the standpoint of definition of terms, using the general linear model of prediction. We also outline types of studies that may be useful in testing potential predictors, and put forward a possible matrix of predictor variables as currently implemented in an NIMH-funded treatment outcome study of pediatric obsessive-compulsive disorder (OCD). We conclude by making specific suggestions for implementing a broader approach to the study of predictors. [ABSTRACT FROM AUTHOR]

Assessment of academic achievement is a very frequent component of evaluation and treatment planning for emotionally handicapped youngsters. However, there is very little information available on the validity of the most commonly used achievement tests with this population. In our study, with a sample of emotionally handicapped children receiving day treatment services, multiple validity indexes were derived for the Wide Range Achievement Test and the Peabody Individual Achievement Test. These included measures of concurrent and construct validity. Results were discussed in terms of the convergent and discriminant validity of subtests, and the accuracy of the estimation of grade level. [ABSTRACT FROM AUTHOR]

Presents a study on the child and adolescent norms for Russell's revision of the Wechsler Memory scale (WMS-R). Use of the WMS-R to assess semantic, figural, immediate and delayed memory; Lack of adequate normative base; Data for six measures of the WMS-R for youngsters; Relationship between memory functioning, age, and verbal intelligence.

Twenty aggressive boys received either an 18-session anger coping intervention (AC) or an 18-session intervention in which anger coping was preceded by self-instruction training on impersonal problem solving and academic tasks (AC-SIT). Anger coping emphasized training in interpersonal cognitive problem-solving skills. Although, contrary to the hypothesis, there were no significant differences between the two conditions in their abilities to reduce passive off-task classroom behavior, the AC-SIT groups did tend to produce stronger reductions in this behavior. The AC groups were significantly more effective in reducing disruptive-aggressive off-task classroom behavior than were the AC-SIT groups. Both forms of cognitive behavioral treatment produced significant increases in on-task classroom behavior, reductions in parents' ratings of boys' aggression, and increases in boys' self-esteem. [ABSTRACT FROM AUTHOR]

The mechanocatalytic formation of carbonaceous films at the interface between sliding metallic contacts is simultaneously advantageous for reducing friction and adhesion in several tribological applications and detrimental for electrical contacts as they can induce device failure by increasing the contact resistance. Yet, remarkably little is still known about the chemistry, structural and mechanical properties, and tunability of these interfacial layers. In this study, we performed contact pressure-dependent tribological experiments in dry nitrogen containing trace organics on four, nanocrystalline Pt–Au alloys ([Au] from 0 at.% to 10 at.%) – a promising class of alloys for ultralow wear and electrical contact applications. The ex-situ , multi-technique characterization results did not only provide insights into the chemical nature and mechanical behavior of the mechanocatalytic, carbon-rich films formed on Pt–Au surfaces, but also revealed the interplay between catalytic and mechanochemical tribofilm formation controlled by the composition-dependent electronic structure of the Pt–Au substrate and the applied contact pressure. The results of this work provide guidelines for tailoring nanocrystalline alloys to control their mechanocatalytic activity on the basis of variations of the alloy mechanical properties and element's electronic structure with the alloy stoichiometry. [Display omitted] [ABSTRACT FROM AUTHOR]

Presents a study that analyzes the relation between specific coping-response preferences and three dimensions of psych ological disturbance in adolescents. Methods; Results; Discussion.

Reassurance seeking, a behavior prominent in anxiety disorders and depression, is associated with poorer quality of interpersonal relationships and acts as a mechanism of stress generation. However, little research has elucidated momentary associations between state anxiety and reassurance seeking behaviors. In a sample of 104 university-affiliated young adults, we sought to replicate cross-sectional associations of reassurance seeking with trait anxiety (Aim 1) and intolerance of uncertainty (Aim 2). We then used ecological momentary assessment (EMA) to evaluate concurrent fluctuations in daily anxiety and reassurance seeking across 14 consecutive days (Aim 3). Hierarchical multi-level models for intensive longitudinal data were used to evaluate the relationship between state anxiety and daily reassurance seeking. In baseline analyses, trait anxiety and intolerance of uncertainty were significantly associated with greater trait reassurance seeking, controlling for depression. Analyses of the EMA data showed that daily reassurance seeking behaviors fluctuated concurrently with daily anxiety during the 14 days, while controlling for trait anxiety and depression. Given evidence of concurrent fluctuations between state anxiety and reassurance seeking, the behavior should be considered as a potential target in treatment for anxiety disorders. • Reassurance seeking is common in anxiety and contributes to interpersonal stressors. • We studied whether reassurance seeking and state anxiety fluctuate together in time. • Individuals sought reassurance more on days of relatively higher state anxiety. • Future work can apply just-in-time interventions to promote effective coping. [ABSTRACT FROM AUTHOR]

Major depressive disorder (MDD) is a common disorder among adolescents. The Treatment for Adolescents with Depression Study (TADS) was a randomized controlled trial to examine the efficacy of fluoxetine and cognitive-behavioral therapy (CBT), separately and together, compared with placebo, in adolescents 12 to 17 years of age. The Survey of Outcomes Following Treatment for Adolescent Depression (SOFTAD) was designed as a naturalistic follow-up of participants in TADS. The aims of the current analyses are to describe mental health service use during the SOFTAD period. There were 196 adolescents recruited from 12 TADS sites. The Schedule for Affective Disorders and Schizophrenia for School-Age-Children-Present and Lifetime Version was used for clinical diagnoses. Participants completed a psychiatric treatment log and the Child and Adolescent Services Assessment to assess service use. 58% received psychotherapy or nonstimulant psychotropic medication during SOFTAD. Youth with recurrent MDD had higher rates of treatment compared to youth without recurrent MDD (71% vs. 45%). However, nearly one third of the adolescents in the study did not receive treatment for a recurrent episode of depression. Service use differed by gender for those with recurrent MDD, with female participants (79%) receiving treatment at higher rates than male participants (55%), although there was no significant difference in depression severity between genders. Younger participants with recurrent MDD had higher odds of receiving psychotherapy. Use of psychotherapy and psychotropics following recurrence of depression appears to be influenced by age and gender. Even when youth respond well to treatment, a sizeable percentage are likely to experience a subsequent episode that may go untreated. [ABSTRACT FROM AUTHOR]

Among adolescents there is evidence that cognitive change partially mediates the effect of cognitive behavioral therapy (CBT) on depression outcome. However, prior studies have been limited by small samples, narrow measures of cognition, and failure to compare cognitive change following CBT to cognitive change following antidepressant medication. This study examined whether change in four cognitive constructs (cognitive distortions, cognitive avoidance, positive outlook, and solution-focused thinking) mediated change in depression severity in a sample of 291 adolescents who participated in the Treatment for Adolescents with Depression Study (TADS). TADS assessed the effects of CBT, fluoxetine, and their combination on depression severity. All three treatments were associated with change in the cognitive constructs and combination treatment produced the greatest change. Furthermore, change in the cognitive constructs partially mediated change in depression severity within all three treatments. Results implicated positive outlook as the construct most associated with change in depression severity over 36 weeks. [ABSTRACT FROM AUTHOR]

Abstract: Despite evidence of ethnic differences in substance use patterns among adolescents in community samples, clinical studies have not found ethnic differences in posttreatment outcomes. Prior clinical studies have been limited by small samples, focus on broad treatment modalities, and lack of consideration of important covariates. We investigated ethnic differences in substance use frequency and problems in a large sample of White (60%), African American (12%), and Latino (28%) adolescents prior to and following an evidence-based treatment. Participants included 4,502 adolescents (29% female), with ages 13–18 years, who received Motivational Enhancement Therapy/Cognitive Behavior Therapy 5 Sessions. At baseline, African American adolescents demonstrated less frequent use, fewer problems, and less comorbidity than Whites or Latinos. Consistent with prior research, there were no ethnic differences in substance use outcomes among assessment completers (71%) when controlling for baseline differences. However, African Americans, older adolescents, and males were less likely to complete the posttreatment assessment. Implications for clinical service and effectiveness research are discussed. [Copyright &y& Elsevier]

Although hopelessness has been linked to depression for centuries, the diagnostic criteria for depression are inconsistent with regard to the status of hopelessness. Most research on hopelessness and depression has focused on adults. The current study examined this relation in children and adolescents. Integrative data analyses with a pooled sample (N = 2466) showed that clinical levels of hopelessness multiplied the odds of having a clinical diagnosis of depression 10-fold. Conversely, not having clinical levels of hopelessness multiplied the odds of endorsing no clinical level of depressive symptoms 28-fold. Moreover, results differed by levels of depression: (a) among youths with clinical levels of depression, hopelessness was associated with six depressive symptoms; (b) among youths without clinical levels of depression, hopelessness was associated with nine depressive symptoms. We found that hopelessness helps to explain the heterogeneity of depressive presentations. Our finding supports the consideration of hopelessness in the diagnosis (if not treatment and prevention) of depression in children and adolescents. (PsycInfo Database Record (c) 2021 APA, all rights reserved). [ABSTRACT FROM AUTHOR]

The article discusses the cognitive-behavioral therapy (CBT) for adolescent depression. Cognitive factors that influence the effectiveness of CBT for adolescent major depressive disorder (MDD) identified include higher levels of rational thoughts, less hopelessness, fewer negative thoughts, and fewer cognitive distortions at baseline. The author also elaborates on Beck's theoretical approach to cognitive therapy and Lewinsohn's multifactorial model.

We present evidence of inverse Hall-Petch behavior for a single-phase high entropy alloy (CoCrFeMnNi) in ultra-high vacuum and show that it is associated with low friction coefficients (~0.3). Grain size measurements by STEM validate a recently proposed dynamic amorphization model that accurately predicts grain size-dependent shear strength in the inverse Hall-Petch regime. Wear rates in the initially soft (coarse grained) material were shown to be remarkably low (~10–6 mm3/N-m), the lowest for any HEA tested in an inert environment where oxidation and the formation of mixed metal-oxide films is mitigated. The combined high wear resistance and low friction are linked to the formation of an ultra-nanocrystalline near-surface layer. The dynamic amorphization model was also used to predict an average high angle grain boundary energy (0.87 J/m2). This value was used to explain cavitation-induced nanoporosity found in the highly deformed surface layer, a phenomenon that has been linked to superplasticity. [ABSTRACT FROM AUTHOR]

Intermetallic alloys possess exceptional soft magnetic properties, including high permeability, low coercivity, and high saturation induction, but exhibit poor mechanical properties that make them impractical to bulk process and use at ideal compositions. We used laser-based Additive Manufacturing to process traditionally brittle Fe–Co and Fe–Si alloys in bulk form without macroscopic defects and at near-ideal compositions for electromagnetic applications. The binary Fe–50Co, as a model material, demonstrated simultaneous high strength (600–700 MPa) and high ductility (35%) in tension, corresponding to a ∼300% increase in strength and an order-of-magnitude improvement in ductility relative to conventionally processed material. Atomic-scale toughening and strengthening mechanisms, based on engineered multiscale microstructures, are proposed to explain the unusual combination of mechanical properties. This work presents an instance in which metal Additive Manufacturing processes are enabling, rather than limiting, the development of higher-performance alloys. Image 1 [ABSTRACT FROM AUTHOR]

Background: More than a decade of war has strained service members and their families and the psychological health of military spouses is a concern. This study uses data from the largest study of military families in the United States to examine the demographic, military-specific, and service member mental health correlates of probable diagnosis of major depressive disorder (MDD) among military spouses.Methods: Data were from service member-spouse dyads from all branches of the U.S. military. Demographic and military-specific factors were assessed using administrative personnel records and survey data.Results: Of the 9,038 spouses, 4.9% had a probable diagnosis of MDD. In unadjusted models, spouses of service members who deployed and experiencecd combat-related events, were enlisted, had a probable posttraumatic stress disorder (PTSD) diagnosis, or screened positive for alcohol misuse were more likely to screen positive for MDD. In adjusted models, only spouses married to enlisted service members or those with PTSD had increased risk for MDD. Other demographic and military-related factors associated with MDD in spouses included less educational attainment, unemployment, having four or more children, and having prior military service (although not currently serving in the military) in the adjusted models.Conclusions: Findings characterize demographic, military, and service member psychological health factors that are associated with depression among military spouses. These findings imply that deployment alone may not negatively affect military spouses, but rather it may be the mental health impact on the service member, especially PTSD that increases the odds for MDD among military spouses. [ABSTRACT FROM AUTHOR]

Molybdenum disulfide (MoS 2) is a popular lamellar material with desirable properties who's form, and function can vary widely, from particles to monolayer/μm thick films and applications in semiconductors to aerospace lubricants and many more. Physical vapor deposition (PVD) is commonly used to produce dense, conformal micron thick MoS 2 coatings, but lacks the ability to coat more complex geometries due to line-of-sight constraints and typically exhibit amorphous or nanocrystalline microstructures. Atomic layer deposition (ALD) has also been employed to deposit monolayer to 10's of nanometers thick lamellar solids like MoS 2 & WS 2 in transistor, sensors or electrocatalyst applications but not commonly for applications as solid lubricants in aerospace like their PVD counterparts. While recent work has shown that ALD MoS 2 can exhibit favorable microstructures for solid lubricant applications and allows for non-line of sight deposition on complex geometries, it has not been widely adopted due to high deposition temperatures (>500 °C) that can lead to softening of steel substrates. In this work, we show one of the first applications highlighting the use of ultra-thin (5–10 nm) low temperature (∼250 °C) MoS 2 coatings as a promising solid lubricant for macroscale mechanical interfaces. Post-deposition chemical conversion of ALD MoO x to MoS 2 by annealing in H 2 S at temperatures ranging from 200 to 550 °C resulted in highly-ordered basally-oriented surface microstructures. The results from this work suggest that converted-ALD MoS 2 coatings can serve as viable solid lubricants for aerospace applications requiring low-temperature processing, including those with complex geometries. • Low-temperature conversion results in basally-oriented MoS 2 coatings • 5–10 nm thick MoS 2 films achieve low wear rates <1 × 10−6 mm3/Nm. • Low initial friction (< 0.1) is achieved at conversion temperatures below 250 °C. • Sustained low friction (∼0.05) is achievable at temperatures as low as 200 °C. • Demonstrate suitability of converted MoS 2 coatings for macroscale applications [ABSTRACT FROM AUTHOR]

Nanocrystalline metal alloys have shown great promise as electrical contact materials, given their mechanical and tribological properties. In particular, platinum-gold (Pt–Au) nanocrystalline alloys have demonstrated coefficients of friction as low as 0.01 and specific wear rates on the order of 10−9 mm3 N−1 m−1, largely due to the formation of carbon-based tribofilms at the sliding interfaces. In this study, we advance our understanding of the Pt–Au tribofilm structure-property relations and growth mechanisms via high-throughput and high-resolution measurements as a function of Pt–Au composition. As the solute content increased from 0 at. % to 10 at. % Au, cross-sectional and plan-view transmission electron microscopy demonstrated a decrease in average grain size d and an accompanied increase in grain boundary (GB) segregation. The decrease in d and increase in GB solute segregation translated to a decrease in modulus E r and an increase in hardness H as determined via nanoindentation; the E r trend was mainly described using a rule-of-mixtures approximation, whereas the H trend was ascribed to solid solution strengthening and GB stabilization. The steady state-friction μ and wear rate decreased with the addition of Au; low Au-content films showed substrate wear, while high Au-content films showed stable tribofilm growth in both macroscale and nanoscale friction tests. The carbon bonding configuration of the tribofilms was investigated by near-edge X-ray absorption fine structure spectroscopic analyses and found to be similar to that of hydrogenated amorphous carbon films. Altogether, the study provided insight into the mechanistic origins of the tribofilms, thus opening the door to tunable properties ranging from mitigation for electrical contacts to the creation of self-healing films for solid lubricants. • Pt–Au nanocrystalline alloys exhibit low friction and wear via tribofilm growth. • Tribofilm structure-property relations revealed for different Pt–Au compositions. • Grain size decreased and grain boundary solute segregation increased as Au increased. • Friction and wear decreased and tribofilm stability increased as Au increased. • Molecular bonding in tribofilms similar to hydrogenated amorphous carbon films. [ABSTRACT FROM AUTHOR]

This study examined the association between parent and family reported history of non-PTSD mental illness (MI), PTSD specifically, and substance use problems, and participant clinical diagnosis of PTSD. Participants were drawn from the US Department of Veterans Affairs Mid-Atlantic Mental Illness Research, Education and Clinical Center (MIRECC) Post-Deployment Mental Health (PDMH) study (n = 3191), an ongoing multi-site cohort study of US Afghanistan and Iraq conflict era veterans. Participants who recalled a father history of PTSD had a 26-percentage point higher likelihood of meeting criteria for PTSD; while participants reporting any family history of PTSD had a 15-percentage point higher probability of endorsing symptoms consistent with PTSD. Mother history of substance use problems was associated with Veteran current PTSD, but results were sensitive to model specification. Current PTSD was not associated with family/parent history of non-PTSD mental illness, mother history of PTSD, or family/father history of substance use problems. Family history of PTSD may increase PTSD risk among veterans exposed to trauma, particularly when a father history is reported. Knowledge of family history could improve clinical decision-making for trauma-exposed individuals and allow for more effective targeting of programs and clinical services. [ABSTRACT FROM AUTHOR]

During childhood and adolescence, physiological, psychological, and behavioral processes strongly promote weight gain and increased appetite while also inhibiting weight loss and decreased appetite. The Diagnostic and Statistical Manual-IV (DSM-IV) treats both weight-gain/increased-appetite and weight-loss/decreased-appetite as symptoms of major depression during these developmental periods, despite the fact that one complements typical development and the other opposes it. To disentangle the developmental versus pathological correlates of weight and appetite disturbance in younger age groups, the current study examined symptoms of depression in an aggregated sample of 2307 children and adolescents, 47.25% of whom met criteria for major depressive disorder. A multigroup, multidimensional item response theory model generated three key results. First, weight loss and decreased appetite loaded strongly onto a general depression dimension; in contrast, weight gain and increased appetite did not. Instead, weight gain and increased appetite loaded onto a separate dimension that did not correlate strongly with general depression. Second, inclusion or exclusion of weight gain and increased appetite affected neither the nature of the general depression dimension nor the fidelity of major depressive disorder diagnosis. Third, the general depression dimension and the weight-gain/ increased-appetite dimension showed different patterns across age and gender. In child and adolescent populations, these results call into question the utility of weight gain and increased appetite as indicators of depression. This has serious implications for the diagnostic criteria of depression in children and adolescents. These findings inform a revision of the DSM, with implications for the diagnosis of depression in this age group and for research on depression. [ABSTRACT FROM AUTHOR]

Our goals in this article were to use item response theory (IRT) to assess the relation of depressive symptoms to the underlying dimension of depression and to demonstrate how IRT-based measurement strategies can yield more reliable data about depression severity than conventional symptom counts. Participants were 3,403 children and adolescents from 12 contributing clinical and nonclinical samples; all participants had received the Kiddie Schedule of Affective Disorders and Schizophrenia for School-Aged Children. Results revealed that some symptoms reflected higher levels of depression and were more discriminating than others. Furthermore, use of IRT-based information about symptom severity and discriminability in the measurement of depression severity was shown to reduce measurement error and increase measurement fidelity. [ABSTRACT FROM AUTHOR]

This study examines ethnic/racial differences at the start of treatment among participants in the Treatment for Adolescents with Depression Study (TADS). African American and Latino youth were compared to Caucasian youth on symptom presentation and cognitive variables associated with depression. Contrary to hypothesis, there were no significant differences in symptom presentation as measured by the interview–based items of the Children's Depression Rating Scale – Revised (CDRS–R). However, African American and Latino youth were both rated as demonstrating more severe symptoms on the observational items of the CDRS–R compared to Caucasian youth. In terms of cognitive variables associated with depression, African Americans reported fewer negative cognitive biases compared to Caucasians, but cognitive biases were significantly correlated with depression severity across ethnic groups. [ABSTRACT FROM AUTHOR]

Objective: In the Treatment for Adolescents with Depression Study (TADS), fluoxetine (FLX) and the combination of fluoxetine with cognitive-behavioral therapy (COMB) had superior improvement trajectories compared to pill placebo (PBO), whereas cognitive-behavioral therapy (CBT) was not significantly different from PBO. Because attention-deficit/hyperactivity disorder (ADHD) and major depressive disorder (MDD) frequently co-exist, we examined whether ADHD moderated these outcomes in TADS.Method: A total of 439 adolescents with MDD, 12-17 years old, were randomized to FLX, CBT, COMB, or PBO. Random coefficients regression models examined depression improvement in 377 depressed youths without ADHD and 62 with ADHD, including 20 who were treated with a psychostimulant.Results: Within the ADHD group, the improvement trajectories of the three active treatments were similar, all with rates of improvement greater than PBO. For those without ADHD, only COMB had a rate of improvement that was superior to PBO.Conclusions: Co-morbid ADHD moderated treatment of MDD. CBT alone or FLX alone may offer benefits similar to COMB in the treatment of MDD in youths with co-morbid MDD and ADHD, whereas monotherapy may not match the benefits of COMB for those without ADHD. The ADHD subgroup analysis presented in this paper is exploratory in nature because of the small number of youths with ADHD in the sample.Clinical Trial Registry: www.clinicaltrials.gov Identifier: NCT00006286. The TADS protocol and all of the TADS manuals are available on the Internet at https://trialweb.dcri.duke.edu/tads/index.html . [ABSTRACT FROM AUTHOR]

Objective: The authors examined whether initial assignment to receive placebo for 12 weeks followed by open active treatment as clinically indicated was associated with different levels of benefit and risk of harm across 36 weeks as corn pared with initial assignment to receive active treatments, Method: Adolescents with major depressive disorder (N 439) were randomly assigned to receive an initial 12 weeks of treatment with fluoxetine, cognitive behavioral therapy (CBT), combination treatment with fluoxetine and CBT, or clinical management with placebo; those assigned to placebo received open active treatment as clinically indicated after 12 weeks of placebo. Assessments were conducted every 6 weeks for 36 weeks. The primary outcome measures were response and remission based on scores on the Children's Depression Rating Scale-Revised and the Clinical Global impression improvement subscale. Results: At week 36, the response rate was 82% in the placebo/open group and 83% in the active treatment groups. The remission rate was 48% in the placebo)/ open group and 59% in the active treatment groups, a difference that approached statistical significance Patients who responded to placebo generally remained their response. Those who did not respond to placebo subsequently responded to active treatment at the same rate as those initially assigned to active treatments. There were no differences between groups in rates of suicidal events, study retention, or symptom worsening. Conclusions: Remission rates at 9 months were lower in patients treated initially with placebo, but 3 months of placebo treatment was not associated with any harm or diminished response to subsequent treatment. [ABSTRACT FROM AUTHOR]

The article presents a study which assesses the long-term outcomes with respect to remission and recovery rates in the treatment for adolescents with depression study (TADS) sample. Twelve weeks medications of fluoxetine, cognitive-behavioral therapy, their combination or pill placebo were utilized to randomized 439 adolescents with major depressive disorder. The results of the later analyses were compared except for the placebo group. The overall remission rate of the intention-to-treat cases at week 36 is 60% which includes 60% in combination, 55% in fluoxetine and 64% in cognitive-behavioral therapy. It adds that nine months of treatment is the tenure where the depressed adolescents attained remission.

Aims: Cannabis use disorder (CUD) and depression frequently co-occur in youth. How depressive symptoms change over the course of CUD treatment and how they impact substance use treatment outcomes is unknown. In the current study, we examine the temporal relationships between cannabis use and depression in adolescents receiving evidence-based treatments for CUD as part of a multisite clinical trial.Design: Six hundred adolescents (age 12-18) with a CUD were randomly assigned to substance use treatment from one of five evidence-based psychosocial interventions. We assessed self-reported cannabis use frequency and depressive symptoms at baseline (BL) and again at 3-, 6-, 9, and 12-months. A bivariate latent change model assessed bidirectional effects of baseline levels and time-lagged changes in depressive symptoms and cannabis use on depression and cannabis use outcomes.Findings: Depressive symptoms (72%) and major depressive disorder (MDD) (18%) were common at BL. Both depression and cannabis use decreased over time and change in cannabis use was significantly associated with change in depressive symptoms (b = 1.22, p = .003). Time-lag analyses showed that within-subject change in depression (from one time point to the next) was predicted by previous depression (b = -0.71, p < .001) but not cannabis use (p = .068), and change (decrease) in cannabis use was predicted by previous (greater) depressive symptoms (b = -1.47, p < .001) but not cannabis use (p = .158), respectively.Conclusion: These findings indicate an enduring relationship between decreasing cannabis use and decreasing depression among adolescents lasting for 9-months after receiving psychosocial interventions for CUD. The presence of depressive symptoms did not appear to interfere with substance use treatment or attenuate improvements in cannabis use frequency. A decrease in cannabis use was not contingent upon a reduction in depressive symptoms. These findings are limited by the possibility of regression to the mean for both cannabis use and depressive symptoms, and the lack of a nonintervention control group. [ABSTRACT FROM AUTHOR]