1. White Blood Cell Type Detection Using K-means Clustering and Multicolor Spaces.
- Author
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Mandal, Sujit, Saha, Manas, and Chatterji, B. N.
- Subjects
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COLOR space , *MACHINE learning , *LEUCOCYTES , *FEEDFORWARD neural networks , *K-means clustering - Abstract
The white blood cell (WBC) plays an instrumental role in protecting the human body from different infectious diseases and unknown biological invaders. Their count and cellular morphology drastically change when the body suffers from any such disease or abnormal conditions. This paper demonstrates the detection of five types of WBC present in human blood smear images. Several authors proposed WBC detection using only one color space. But this paper addresses WBC-type detection using four popular color spaces – RGB (red, green, and blue), HSV (hue, saturation, and intensity), YCbCr (luminance, chroma blue, and chroma red), and L*a*b* (luminosity, chromaticity layer "a*", and chromaticity layer "b*"). The proposed methodology involves color thresholding, K-means clustering, nuclear region analysis, and the implementation of a feedforward neural network. The unsupervised machine learning algorithm, K-means clustering is used to segment nuclei from the blood smear images. The detection of WBC-type using four color spaces is compared in terms of accuracy, sensitivity, specificity, and positive predictive value. It is observed that HSV-based WBC-type detection methodology outperforms methodologies based on RGB, YCbCr, and L*a*b* color spaces. The same methodology mentioned above is then compared with the works proposed by other authors. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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