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Background: Autoimmune encephalitis occurs as a subacute condition with a strong infectious association in children. In the last 20 years, the frequency of non-infectious cases has increased significantly. Clinical case: A previously healthy eight-year-old male child with normal neurodevelopment, without a history of consanguinity, manifested progressive neurological deterioration with autoimmune encephalitis-limbic encephalitis up to hypothalamic dysfunction. Conclusion: In the mentioned case, it was documented that an inborn error of the immune system generated a severe neurological clinical picture, with permanent and irreversible damage, secondary to lack of immunological memory in the broad clinical context of a common variable immunodeficiency. [ABSTRACT FROM AUTHOR]

The present article shows the socio-technical construction of two research experiences: ceramic polymers and transgenic potatoes. Both of them pretend to constitute themselves as an alternative of analysis to the studies that highlight the fundamental role of the technology in the explanation of the globalisation. This text shows two ethnographies of laboratory. In the case of the polymers, it is showed how the construction of a local knowledge is internationally expanded; in the second case, the transgenic potatoes being a knowledge that it has begun to be known all over the world, it is necessary to situate it locally in its process of research. [ABSTRACT FROM AUTHOR]

The article focuses on the importance of quality professional development for teachers due to the challenges and expectations they face for high quality education. Professional development is a vital component for ongoing teacher education. This development is committed to improve teacher's instructional methods, their ability to adapt education to meet student needs and their classroom management skills. Activities related to professional development designed for teachers provide them with useful tools to understand academic disciplines and pedagogical principles.

Immunoglobulins are heterodimeric proteins composed of 2 heavy chains and 2 light chains. Human immunoglobulin G (IgG) is a plasma derivative and contains more than 95% of IgG. The composition of IgG subclasses is similar to that of normal human plasma. Immunoglobulin therapy was first introduced more than 50 years ago, and its use has been described in numerous diseases. In Colombia, the importance of this immunomodulatory resource prompted the need for clinical practice guidelines to be available for its use. For this reason, a multidisciplinary group of experts was brought together and distributed in working groups, by specialties, in order to develop an initial manuscript. Systematic literature searches were undertaken; identified evidences were evaluated and classified to support a preliminary draft that was discussed, analyzed and amended. Recommendations were issued on the use of intravenous immunoglobulin in pathologies that include primary and secondary immunodeficiencies, autoimmune diseases, neurological disorders, infections, transplants and miscellaneous conditions; grades were assigned to each one of them according to the GRADE system. The final result translated into recommendations that are put forth with the purpose to inform, guide and support on optimal use of this immunomodulatory resource. [ABSTRACT FROM AUTHOR]