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The article presents a study of facial cellulitis and Ludwig's angina associated with calcium hydroxylapatite injection in a 30-year-old female presented with swelling, rise of temperature, and tenderness on her right lower cheek. The patient received intravenous ampicillin/sulbactam after administering oral antibiotics including cefadroxil, amoxicillin and rifampicin. A computed tomography scan revealed complete resolution of the soft tissue inflammation.

Generalized pustular psoriasis (GPP) is a rare, potentially life‑threatening skin disease characterized by relapsing and remitting flares of sterile neutrophilic pustules and systemic inflammation. The definition of GPP is inconsistent globally, with large discrepancies in clinical management. To provide clinical guidance on managing GPP, we conducted a systematic literature search for articles published within the last decade on PubMed and the Cochrane Library in October 2022 and held four consensus meetings with 12 Taiwanese dermatologists between October 2022 and July 2023. Upon review of 153 articles, we agreed to adopt the European Rare and Severe Psoriasis Expert Network GPP definition with additional clarifications on pustular flares in psoriatic plaques, circinate or annular lesions, and localized pustules. We also drafted a diagnostic algorithm to facilitate GPP diagnosis. Twenty‑seven statements on GPP treatment reached consensus. We recommend using an oral retinoid or spesolimab injection for the first‑line treatment in both acute (treating flares) and maintenance (preventing flares) settings in adults with GPP. For infants and juveniles with GPP, retinoids are recommended as a first‑line treatment. Evidence for other conventional and investigational therapies was reviewed, and a treatment algorithm was proposed. We hope this consensus provides practical guidance for clinicians in Taiwan and helps improve outcomes for GPP patients. [ABSTRACT FROM AUTHOR]