Search

Throughout the different ages, several texts attributed to Virgil have circulated apart from his three major works. Some of them are poems included in the Appendix Vergiliana; others are collected in the Carmina XII sapientum; and we even find some anecdotes that Donatus offers in the poet's life. In this work, we examine a selection of extracts collected in three 16th-century florilegia: the Illustrium poetarum flores (Strasbourg 1538), by O. Mirandula; the Sententiae ueterum poetarum (Antwerp 1541), by G. Maior; and the Versus Sententiosi et eximii (Wittenberg 1565), by B. Schönborn. We also deal with several fragments of the Libri XIII Aeneidos Supplementum by Maffeo Vegio, which is reproduced in Mirandola's compilation. The presence of texts linked to Virgil in the florilegia could indicate that the prestige he enjoyed in the Middle Ages extended into the Renaissance. In addition, in G. Maior's work there are doubts about the authorship of the texts presenting a moral and pedagogical tone, implying that moral and didactic interests may have motivated the selection. [ABSTRACT FROM AUTHOR]

Background Frequently, haematological patients undergo highly complex and intensive treatment protocols, so a high risk of drug–drug interactions could be expected. Objectives To determine prevalence of clinically relevant drug–drug interactions, to identify the most frequent drug–drug interactions and associated risk factors. Methods A prospective, observational and descriptive study was carried out from November 2012 to February 2013. Twice a week, every patient’s treatment sheet was collected. Each medication list was screened through two databases: Thomson MicromedexTM and Drug Interaction FactsTM. All identified potential drug–drug interactions with a moderate or higher severity rating were recorded. Summary statistics were used to describe patient and disease characteristics, most often prescribed drugs, and frequency, types and classification of drug–drug interactions. Multiple logistic regression models were used to identify risk factors associated with drug–drug interactions. Results A total of 2061 drug–drug interactions were detected in 317 treatment sheets from 58 patients. The prevalence of treatment sheets with drug–drug interactions by Micromedex and Drug Interaction Facts databases were 74.1% and 56.8%, respectively. Azole antifungals, immunosuppressive drugs, antiemetics, antidepressants, acid suppressants and corticosteroids were the most frequent involved drugs. In multivariate analysis, the main risk factor associated with increased odds for drug–drug interactions was a higher number of non-antineoplastic drugs. Conclusions The prevalence of drug–drug interactions was common, with immunosuppressant and azole antifungal agents being the most commonly involved drugs. The factor having the greatest influence on drug–drug interactions was a higher number of non-antineoplastic drugs. [ABSTRACT FROM AUTHOR]

The article presents the discussion on extravasation management remains an area where good quality evidence is very limited. Topics include managing extravasation, one based on pharmacological and physical or non-pharmacological measures, and another based on surgical procedures; and assessing the potential risk of tissue-damage and the effectiveness of the implemented strategies.

Background Although second intention healing has been used for many years in Mohs micrographic surgery, it has lost popularity. This is due to the long process and functional alteration of important anatomical units if certain wound healing factors are not carefully taken into consideration. Objective To review indications, contraindications, complications, advantages, disadvantages, as well as basic concepts of the wound healing process, wound care and antibiotic prophylaxis in the management of open wounds after Mohs surgery. Methods A short but comprehensive review of studies published in the literature dealing with second intention healing as a reconstruction alternative option in certain situations. Conclusions Second intention healing is a simple and cost-effective method for reconstruction after Mohs micrographic surgery in well-defined cases. It allows adequate tumoral control with good to excellent functional and cosmetic results. [ABSTRACT FROM AUTHOR]

The Ruins of Oxpemul, Campeche represent a fortified royal court in the Peten Campechano and the Calakmul Basin some 25 kms north of the major regional center of Calakmul. Oxpemul's larger nucleus to the north is perched on a 45.50 m high mesa. Its settlement pattern closely resembles that of Calakmul and El Mirador. There is a smaller nucleus to the south. Oxpemul has 21 stelae with some 18 altars fronting them. Many of the stelae with human figures and hieroglyph texts are standing and well preserved. Several altars are also graced with texts with one appearing to be a deity figure. Oxpemul is associated with a stone throne emblem glyph that appears in texts five or more times. A 9 km² map has been made of the area surrounding Oxpemul's two nuclei that includes several major and minor groups as well as aguadas, canteras and sascaberas. [ABSTRACT FROM AUTHOR]