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Creative destruction used by German sociologist Werner Sombart in 1913, and later known as Schumpeter's gale, could be considered the first conceptual stage of what happens nowadays in all industries "forced" to use the digital environment. First three industrial revolutions experienced by the humanity happened in over three centuries with tangible results that improved immensely the day-to-day life of people. The fourth one happened in decades, and it was characterized by the use of information and communication technology in various industries. As the literature review has revealed, Internet of Things (IoT) is part of Industry 4.0., linking industries and consumers in a smarter way through sensors and other devices, collecting valuable data and helping companies. This article proposes a navigation throughout the literature to demonstrate that IoT is a new and modern solution that has a big potential for development to help businesses to take smarter and swifter decisions from data gathered indirectly from consumers. Given that the papers analyzed are quite recent, we would say that this topic of IoT is only lightly investigated, and it opens many subjects of discussions, not only on the business and marketing side, but also economically, socially, and of course, technically. Various questions have arisen during the research: Is there a limitation in using this instrument in business and marketing strategies? Either technical or legal? The ethics of this process is under question and both companies and governments dedicated a lot of time to understand the implications of IoT in the future. [ABSTRACT FROM AUTHOR]

Cancerul de col uterin ocupă locul doi pe plan mondial în cadrul tumorilor maligne la femei, cu o incidență de aproximativ 528.000 de noi cazuri raportate anual și aproximativ 266.000 de decese raportate în 2012. Există o legătură strânsă între prezența virusului papiloma uman (HPV), cancerul de col uterin și al precursorilor săi. HPV poate fi identificat în mai mult de 99% din totalul cazurilor de cancer de col uterin, iar infecția cu HPV este acum acceptată că o cauză necesară pentru majoritatea cancerelor de col uterin. Toate pacientele diagnosticate cu carcinom invaziv de col uterin vor trebui evaluate clinic prin examen vaginal și rectal, imagistic prin tomografie computerizată, rezonanță magnetică nucleară sau PET-CT. Sistemul FIGO este cel mai utilizat sistem pentru stadializarea cancerului de col uterin. Sistemul de stadializare FIGO este bazat în special pe examinare clinică, de aceea examinarea pelvină efectuată de un clinician cu experiență este de o importanță critică. Numeroși factori influențează alegerea tratamentului pentru cancerul de col uterin, incluzînd dimensiunea tumorii, stadiul, caracteristicele histologice, evidența invaziei ganglionilor limfatici, factorii de risc în apariția complicațiilor post-intervenție chirurgicală sau radioterapie și preferințele pacientelor. În principiu, în carcinomul microinvaziv (std. IA1) tratamentul de elecție este reprezentat de chirurgia conservativă (conizație excizională sau histerectomie extrafascială). În cancerele invazive în stadii incipiente (std. IA2, IB1, unele IIA) tratamentul de elecție este reprezentat de histerectomie radicală sau histerectomia radicală modificată, trachelectomia radicală (dacă se dorește prezervarea fertilității) sau radioterapia. În cancerele local avansate (std. IB2 până la IVA) tratamentul de elecție este reprezentat de radiochimioterapie. Tratamentul la pacientele cu boală metastatică este reprezentat în principal de chimioterapie sistemică, însă bolnavele sunt încurajate să participe la studii clinice. [ABSTRACT FROM AUTHOR]

Cervical cancer ranks second worldwide in the malignancies in women, with an incidence of approximately 528,000 new cases reported annually and approximately 266,000 deaths reported in 2012. There is a strong link between the presence of human papillomavirus (HPV) cervical cancer and its precursors. HPV can be identified in more than 99% of all cases of cervical cancer and HPV infection is now accepted as a necessary cause for the majority of cervical cancers. All patients diagnosed with invasive cervical carcinoma should be evaluated clinically by vaginal exam and rectal imaging by computed tomography, magnetic resonance imaging or PET-CT. FIGO system is most widely used staging system for cervical cancer. FIGO staging system is mainly based on clinical examination, pelvic examination therefore performed by a clinician with experience, which is critically important. Many factors influence the choice of treatment for cervical cancer, including tumour size, stage, histological characteristics and lymph node invasion obvious risk factors for complications after surgery or radiotherapy and patients' preferences. Basically, in micro invasive carcinoma (std. IA1) the treatment of choice is conservative surgery (excisional conisation or hysterectomy extra fasciala). In invasive cancers in early stages (std. IA2, IB1, some IIA) the treatment of choice is radical hysterectomy or modified radical hysterectomy, radical trachelectomia (if desired fertility preservation) or radiotherapy. In locally advanced cancers (std. IB2 to IVA) the treatment of choice is radio chemotherapy. Treatment of patients with metastatic disease is primarily systemic chemotherapy, but the patients are encouraged to participate in clinical trials. [ABSTRACT FROM AUTHOR]