1. Efficacy of Listerine®, Meridol® and chlorhexidine mouthrinses as supplements to regular tooth-cleaning measures.
- Author
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Brecx, M., Brownstone, E., Macdonald, L., Geiskey, S., and Cheang, M.
- Subjects
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HEALTH education , *MEDICAL communication , *CHLORHEXIDINE , *BIGUANIDE , *TOOTH care & hygiene , *PREVENTIVE dentistry - Abstract
The anti-plaque. anti-gingivitis and anti-microbial efficacies of a phenolic compound (Listcrine®) and 2 different amine/stannous fluoride mouthwashes (Meridol® I, II) were compared when these solutions were used in addition to usual toothcleaning. A placebo preparation was utilized as a negative control and a chlorhexidine solution as a positive control in this double-blind study. After professional toothcleanling, 49 volunteers continued their habitual, self- performed and non-supervised oral hygiene for a period of 2 weeks, in order to have a more standard baseline. At day 0. they began to rinse twice daily with 1 of the 5 mouthwashes. After 3 weeks of rinsing, plaque indices remained the lowest in the chlorhexidine and the Meridol® I groups, while subjects using Listerine® or Meridol® II demonstrated similar indices significantly lower than that of individuals rinsing with the placebo solution. Through this period, the gingival index scores were similar in the Meridol® Listerine® and chlorhexidine groups. At day 21, the mean GI scores in the chlorhexidine group were significantly lower than the scores in the placebo group. The plaque vitality scores showed a bacterial effect in vivo of chlorhexidine and, to a lesser extent, of the Meridol® solutions. No substantial evidence of an antibacterial effect in vivo was found for Listerine®. This study has demonstrated that when mouthrinses are used to supplement habitual mechanical oral hygiene, chlorhexidine remains the most powerful solution. Furthermore, it was also shown that a combination of habitual self-performed and non-supervised oral hygiene with Meridol® or Listerine® is more beneficial for plaque control than the use of mechanical oral hygiene alone. [ABSTRACT FROM AUTHOR]
- Published
- 1992
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