1. Seroprevalence of Anti--Toxoplasma Gondii Antibodies in Healthy Voluntary Blood Donors from Mashhad City, Iran.
- Author
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Zarean, Mehdi, Shafiei, Reza, Gholami, Maryam, Fata, Abdolmajid, Balaghaleh, Mansour Rahmati, Karimi, Ashraf, Tehranian, Farahnaz, Hasani, Ali, and Akhavan, Arash
- Subjects
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AGE distribution , *BLOOD transfusion , *ENZYME-linked immunosorbent assay , *IMMUNOGLOBULINS , *METROPOLITAN areas , *PARASITES , *PROBABILITY theory , *RESEARCH , *SEX distribution , *STATISTICS , *SEROPREVALENCE , *TOXOPLASMOSIS , *DATA analysis software , *DESCRIPTIVE statistics , *DISEASE risk factors - Abstract
Objective: The present investigation aims to evaluate the prevalence of IgM and IgG anti-7, gondii antibodies and the associated risk factors among healthy blood donors in Mashhad city, Razavi Khorasan province, Iran. Methods: We screened a total of 500 serum samples by census method from apparently healthy blood donors of the Mashhad Blood Transfusion Organization (MBTO) for IgG and IgM anti-T gondii antibodies by enzyme linked immunosorbent assay (ELISA). Results: We found that 29.6%, 25%, 1.4%, and 3.2% of tested donors were positive for anti-T gondii antibodies, only IgG antibody, both IgM and IgG, and IgM antibody alone, respectively. Several risk factors which were significantly related to T gondii seropositivity in the univariate analysis at P < 0.05 included female gender (OR = 3.222, P < 0.001), age more than 40 years (P = 0.026), and sausage/hot dog consumption (OR = 4.472, P < 0.001). Conclusions: The results of this study can be a warning for blood transfusion organizations to pay special attention to toxoplasmosis among blood donors and also design screening programs for prevention of transfusion-transmitted toxoplasmosis. sis [ABSTRACT FROM AUTHOR]
- Published
- 2017