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Objective: To investigate the predictive value of serum amyloid A (SAA), C-reactive protein (CRP), platelet distribution width (PDW) and neutrophil/lymphocyte ratio (NLR) for the timing of neonatal necrotizing enterocolitis (NEC) surgery.Methods: 70 children with NEC who were admitted to Foshan Maternal and Child Health Hospital from January 2019 to January 2022were selected, and they were divided into surgery group with 35 cases and non-surgery group with 35 cases according to treatment methods. Clinical data of children with NEC were collected, and the levels of serum SAA, CRP, peripheral blood PDW and NLR in the two groups were detected. Univariate and multivariate Logistic regression were used to analyze the influencing factors of neonatal NEC surgery. The predictive value of serum SAA, CRP, peripheral blood PDW and NLR on the timing of neonatal NEC surgery was analyzed by receiver operating characteristic (ROC) curve. Results: The gestational age ≥37 weeks and the proportion of weight ＞2500 g at diagnosis in the surgery group were lower than those in the non-surgery group, the proportion of weight 1500～2500 g at diagnosis, poor mental response, abdominal distension, weak bowel sound and the levels of serum SAA, CRP, peripheral blood PDW and NLR were higher than those in the non-surgery group (all P＜0.05). Multivariate Logistic regression analysis showed that weight＞2500 g at diagnosis was an independent protective factor for neonatal NEC surgery, poor mental response, abdominal distension, weak bowel sound and increased levels of serum SAA, CRP, PDW and NLR were independent risk factors for neonatal NEC surgery (all P＜0.05). ROC curve analysis showed that the area under the curve (AUC) of the combination of serum SAA, CRP, peripheral blood PDW and NLR in predicting the timing of neonatal NEC surgery was greater than that of each indicator alone. Conclusion: The increase levels of serum SAA, CRP, peripheral blood PDW and NLR are closely related to neonatal NEC surgery, and the combined value of these four indicators in predicting the timing of neonatal NEC surgery is higher [ABSTRACT FROM AUTHOR]

In order to research the effects of tillage methods on the growth of wheat at early stage and soil moisture in Sichuan hilly areas, three tillage methods (no-tillage, rotary tillage and conventional tillage) were used as main plots and straw-mulching or no straw-mulching as sub-plots, and the effect of tillage methods on reducing the negative influence of seasonal drought on the growth of wheat at early stage in those regions were discussed under split plot field experiments. The results showed that straw-mulching could significantly accelerate the hap pening of tillers and improve the chlorophyll contents ( SPAD value ), leaf area index ( LAI) and population dry matter accumulation, respectively, however, the root activity was lower than that of no straw-mulching treatment at tillering stage. Under no-tillage condition, the winter wheat had stronger tillering ability, higher LAI and population dry matter accumulation, but there was not significant between rotary tillage and conventional tillage. There were no significant effects of three tillage methods on the SPAD value and root activity of winter wheat. In addition, straw-mulching had remarkable effect on soil water preservation, especially at 0 - 20 cm soil layer, and the soil moisture with straw-mulching was higher by 8. 0 % - 16. 7 % as compared to no straw-mulching. Furthermore, no-tillage could also promote soil water preservation, but this function reduced along with the growth of winter wheat. Based on these results, it was concluded that straw-mulching and no tillage could significantly promote the growth of wheat at early stage as well as soil water preservation effect and could effectively reduce the negative effects of seasonal drought on the growth of wheat at early stage in this region. [ABSTRACT FROM AUTHOR]