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Objective To investigate the efficacy of drawer-genioplasty in correcting the long-chin deformity and preventing postoperative sagging of submental soft tissues. Methods Forty-two patients with long-chin deformity admitted to the Department of Craniomaxillofacial Surgery, Plastic Surgery Hospital from October 2020 to December 2023 were selected for this study. The modified drawer-genioplasty was performed through an intraoral incision approach, using subapical and mandibular contouring osteotomy. The osteotomy lines were designed and performed during surgery to minimize damage to the bone attachments of the anterior belly of the digastric muscle, mylohyoid muscle, and geniohyoid muscle to protect the floor-of-mouth muscles adequately. Digital technology enabled the assessment of surgical outcomes through the analysis of three-dimensional reconstruction of bone and facial scanning. Follow-up visits were conducted 6-12 months post-surgery. Results All patients achieved uncomplicated primary healing at gingiva-labial sulcus incisions, without any occurrences of hematoma, infection, or bone necrosis. The digital analysis revealed a postoperative ratio change of 1:0.86 between the chin bones and soft tissues. Measurements demonstrated an increase in R1 (the ratio of the middle and lower face) from preoperative 0.82±0.09 to postoperative values 0.92±0.11, as well as an increase in R2 (the ratio of the upper and lower lips) from preoperative 0.52±0.06 to postoperative values 0.63±0.05. However, there was an increase in the mentocervical angle from preoperative 104.90°± 8.02° to postoperative 111.50°±7.03°, this value was still within the normal range. The results above demonstrated statistically significant differences (P<0.05). Two patients experienced transient lower lip numbness postoperatively, which resolved at four months and ten months respectively. All patients expressed satisfaction with their postoperative facial contour morphology. Conclusion The modified drawergenioplasty demonstrates both safety and efficacy in correcting patients with long chin deformity, while effectively preventing postoperative sagging of the submental soft tissues, thereby exhibiting significant clinical applicability. [ABSTRACT FROM AUTHOR]

目的 探讨BMI与胃癌临床病理参数、手术并发症及预后的关系。方法 行根治手术治疗的胃癌患者466例,根据术前BMI将患者分为体重过低组(BMI<18.5)64例、正常体重组(BMI 18.5~24.0)256例、超重组(BMI≥24.0)126例。收集三组患者年龄、性别、术前血红蛋白水平、术前白蛋白水平、术后病理分化程度、肿瘤最大径、肿瘤浸润深度、淋巴结清扫数目、淋巴结转移情况、TNM分期、手术并发症、围手术期死亡及预后情况等资料,并进行分析。结果三组淋巴结转移分期(N分期)及转移淋巴结数目相比,P均<0.05。胃癌患者术前BMI与术前血清白蛋白水平呈正相关关系(r=0.120,P=0.019),与手术清扫淋巴结数目呈负相关关系(r=-0.168,P=0.001),与转移淋巴结数目呈正相关关系(r=0.163,P=0.001)。466例患者中80例(17.9%)出现术后并发症,体重过低组、正常体重组、超重组发生术后并发症的例数分别为10、40、30例,三组相比,P均>0.05。8例患者围手术期死亡,其中体重过低组1例、正常体重组4例、超重组3例,三组相比,P均>0.05。体重过低组、正常体重组、超重组5年生存率分别为30.6%、43.7%、26.1%,三组相比,P均<0.05。单因素分析结果显示,BMI与患者生存相关;多因素分析结果显示,BMI并非胃癌的独立预后因素。结论术前BMI与胃癌患者血清白蛋白水平、手术清扫淋巴结数目及转移淋巴结数目有关。胃癌患者术前BMI与手术并发症无明显关系,但与胃癌患者预后有一定关系,BMI过高或过低者预后较BMI正常者差。 [ABSTRACT FROM AUTHOR]

[Objective] This study is aimed to decode the genomic sequence of Mycoplasma ovipneumoniae strain GH3-3, to investigate its pathogenic potential and to elucidate the regulatory mechanisms of its replication, transcription, and translation. [Method] M. ovipneumoniae GH3-3 strain was cultured in vitro. When it reached the late logarithmic stage of growth, the genomic DNA of M. ovipneumoniae GH3-3 strain was extracted with bacterial genomic DNA extraction kit and sent for whole genome sequencing and commentary. [Result] The genome size of GH3-3 strains of M. ovipneumoniae was 1 060 772 bp, and the GC content was 29.66%. The genome component analysis showed that the genome of GH3-3 strain contained 730 coding genes, with a total length of 914 379 bp and an average length of 1 252.57 bp, accounting for 86.2% of the total genome length. There were 149 tandem repeats with a total length of 20 926 bp, accounting for 1.97% of the total length of the genome. There were 102 microsatellite DNA sequences, 30 tRNA sequences, and 3 rRNA sequences. The 719, 459, 473, 394, 449, 33, 5, 180, 113 and 59 genes were annotated in NR, SwissProt, GOG, KEGG, GO, CARD, CAZy, PHI, TCDB, and RMS databases, respectively. A total of 76 virulence factor-related genes were annotated. The genome sequence was submitted to the NCBI website with the login number: PRJNA1051969. [Conclusion] The complete genome information of M. ovipneumoniae GH3-3 strain was acquired, and the gene function was predicted and annotated. Furthermore, the genetic and evolutionary relationships between GH3-3 strain and other strains of M. ovipneumoniae were elucidated globally [ABSTRACT FROM AUTHOR]

Objective To explore the efficacy of plastic suture technique in the emergency surgical treatment of superficial facial trauma. Methods The clinical data of patients with superficial facial trauma underwent plastic suture technique treatment from January 2012 to January 2018 were retrospectively reviewed. Preoperative, seventh-day and sixth-month postoperative photographs were taken. The baseline information, type of trauma, location, length and depth of wounds, details of operative procedures, complications, appearance of scars and patients' satisfaction were recorded. Results A total of 720 patients were included in this study. The age of patients ranged from 2 to 76-year-old, with an average of 17.89-year-old. The follow-up period ranged from 6 to 11 months, with an average of (8.15± 3.21) months. The types of trauma were laceration (93.75%), contusion (2.50%), animal bite wounds (1.25%), human bite wounds (0.42%) and other wounds (2.08%). The forehead (20%), eyebrow and upper eyelid (20%), mandible and chin (20%) were the most common injury locations, followed by lip (15%), cheek (10%), nose (5%), temporal region (5%) and other parts (5%). The average length of wounds was (3.25±2.17) cm. The wounds of forehead and chin were deep to bony surface and other parts were deep to subcutaneous layer. The incidence rate of complications was 0.30%. The postoperative scar was not obvious in most patients. The efficacy was satisfactory. Conclusion The application of plastic suture technique in the treatment of emergency facial trauma could obtain good function and aesthetic effect. The postoperative complications are rare and the scars are not obvious. Patients' satisfaction is high. [ABSTRACT FROM AUTHOR]

目的　探讨酰胺质子转移（ＡＰＴ）磁共振成像用于缺血性脑梗死分期的可行性。方法　５０例脑梗死患 者（发病时间＜２４ｈ者１５例、２４～７２ｈ者９例、＞７２～２４０ｈ者１２例、＞２４０ｈ者１４例），接受头颅ＡＰＴ磁共振成 像检查，计算酰胺质子的不对称磁化转移率（ＭＴＲａｓｙｍ）。结果　发病时间＜２４ｈ、２４ ～７２ｈ、＞７２ ～２４０ｈ、＞２４０ ｈ脑梗死患者的ＭＴＲａｓｙｍ分别为－０．９±０．６、－０．２±０．６、０．２±０．５、０．９±０．７；发病时间＜２４ｈ、２４～７２ｈ脑梗死 患者的ＭＴＲａｓｙｍ相比，Ｐ＜０．０１；发病时间＜２４ｈ、＞７２～２４０ｈ脑梗死患者的ＭＴＲａｓｙｍ相比，Ｐ＞０．０５；发病时间＜ ２４ｈ、＞２４０ｈ脑梗死患者的ＭＴＲａｓｙｍ相比，Ｐ＜０．０１；发病时间２４～７２ｈ、＞７２～２４０ｈ脑梗死患者的ＭＴＲａｓｙｍ相 比，Ｐ＜０．０１；发病时间２４～７２ｈ、＞２４０ｈ脑梗死患者的ＭＴＲａｓｙｍ相比，Ｐ＜０．０１；发病时间＞７２ ～２４０ｈ、＞２４０ｈ 脑梗死患者的ＭＴＲａｓｙｍ相比，Ｐ＜０．０１。结论　发病时间不同脑梗死患者的ＭＴＲａｓｙｍ不同，ＡＰＴ磁共振成像检查 有助于缺血性脑梗死的分期。 [ABSTRACT FROM AUTHOR]

目的分析进展期胃癌患者胃癌根治术后复发的危险因素。方法 383例行胃癌根治术治疗的进展期胃癌患者纳入本研究,收集383例患者的临床资料,随访观察其术后复发情况,分析胃癌根治术后复发的危险因素。结果 383例患者中156例(40.7%)出现术后复发,其中早期复发105例(67.3%),晚期复发51例(32.7%)。淋巴结清扫范围、T分期、N分期、TNM分期及术后有无化疗与进展期胃癌患者胃癌根治术后复发有关(P均<0.05),而年龄、性别、肿瘤部位、Borrmann分型、胃切除范围、术后病理分化程度及肿瘤最大径与肿瘤复发无关(P均>0.05)。早期复发者与晚期复发患者在N分期、TNM分期间差异有统计学意义(P均<0.0.5)。淋巴结清扫范围与术后有无化疗是进展期胃癌患者胃癌根治术后复发的独立危险因素因素(P均<0.05)。结论淋巴结清扫及术后有无化疗是进展期胃癌患者胃癌根治术后复发的危险因素。 [ABSTRACT FROM AUTHOR]

Objective To explore the clinical application of "cruciform" ear cartilage scaffold and alar groove plasty in tip rhinoplasty. Methods In a retrospective study from January 2014 to December 2017, 37 patients underwent dorsum and tip augmentation with alar grove plasty using the technique. All patients underwent primary augmentation rhinoplasty or a second revision following a simple silicone implant to the dorsum. During the operation, a silicone implant was used for dorsum augmentation. Autologous ear cartilage was harvested and dissected to form a "cruciform" cartilage scafford for tip augmentation. The subcutaneous tissue under desired alar groove area was properly thinned to allow reattachment under percutaneous trans-fixation for 4 to 7 days. Results All patients the postoperative results were mainly satisfying with tip augmentation and a better-defined alar grove. Postoperative courses were uncomplicated during a 6 to 24 months follow-up without tip extrusion, infection, and graft shifting. Conclusion The combined technique is safe and effective in nasal dorsum and tip augmentation with alar grove improvement. It defines the tip and the alar groove area while minimizing the risk of early stage graft shifting in a relatively simple and less invasive way, postoperative appearance is better than before. [ABSTRACT FROM AUTHOR]

面部填充剂是在盲视下通过微针注射的。若操作不当，加之透明质酸（hyaluronic acid，HA）注射物本身的流体特 点，有一定的概率导致面部血管支配区域血运障碍并可能出现较严重的视力损伤。对其治疗，目前临床上常见的合理有效的治 疗方案是针对性地进行球后透明质酸酶（hyaluronidase, HAase）注射和选择性地进行眼动脉造影溶栓。现对HA 面部填充注射引 起视力损伤的原因、发病机制及预防策略结合近年文献作一综述。 [ABSTRACT FROM AUTHOR]

Objective To explore the effect of mandibular angle osteotomy (MAO) on morphological changes in male patients and to summarize the critical surgical points. Methods Between April 2015 and November 2018, 20 male patients with mandibular angle hypertrophy in our department were retrospectively analyzed. Morphological changes of the mandible were accurately evaluated by three-dimensional computed tomography (CT) reconstruction before and after the MAO. The surgical techniques were also summarized. Results All patients were followed up from 6 to 12 months and were satisfied with the efficacy of MAO. No complications such as hematoma, infection and facial nerve injury occurred. Before and after the MAO, the height of mandibular body under the second molar was significantly different, but there was no significant difference in the distance between the mandibular angle (P>0.05). The osteotomy volume was positively correlated with the height of the mandible, the maximum width of the osteotomy area and the width of mandible ramus at the level of occlusal plane. There was no correlation between the volume of postoperative blood loss and the osteotomy volume. Con-clusion MAO has a good effect on the improvement of lower facial contour in male patients. Attention should be paid to the operation details and techniques to obtain better aesthetic outcomes and reduce the risk of postoperative complications. [ABSTRACT FROM AUTHOR]