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Milking equipment can be the main source of milk contamination by microorganisms, since milk, which remains in the unevenness of the milk line and separate parts of the apparatus, is a favorable environment for the reproduction of microorganisms. Timely washing and disinfection of milking equipment and dairy equipment is the key to obtaining safe milk of high quality. We have developed a new washing-disinfectant "Argomol" for the sanitation of milking equipment. When choosing a washerdisinfectant for sanitation of dairy equipment, attention should be paid not only to its effective bactericidal and other actions, but also to possible toxicity. This article is devoted to the preclinical investigation of the washing-disinfectant means "Argomol" for determining cumulative, irritating, sensitizing and skinresorptive actions of a remedy for the organism of laboratory animals. The investigation were carried out according to the methodological recommendations "Assessment of the suitability and effectiveness of detergents, disinfectants and washing-disinfectants for the sanitary treatment of milking equipment and dairy equipment". It is proved that the washingdisinfectant means "Argomol" does not have a pronounced cumulative, irritating, sensitizing and skin-resorptive effect. It is established that the washing-disinfectant means "Argomol" according to the classification of substances for toxicity (GOST 12.1.007-76) refers to the 4th toxicity class. [ABSTRACT FROM AUTHOR]

Milk microflora is formed mainly due to the microorganisms entering it from the surfaces of milking equipment and dairy equipment. Therefore, an important condition for ensuring the minimum quantity and optimal qualitative composition of the microflora of milk is the proper sanitary treatment of milking equipment and dairy equipment and the compliance with sanitary requirements during the initial processing and storage of milk. This article is devoted to the study of bactericidal activity of the new detergent disinfectant "Argomol" concerning the microflora that occurs on the surface of dairy equipment and negatively affects the safety and quality of milk and dairy products - S. aureus and E. coli. The research was carried out in accordance with the Recommendations on sanitary-microbiological study of flushing from the surfaces of test objects and objects of veterinary supervision and control. It has been proved that under conditions of in vitro growth of S. aureus and E. coli, there are no 0.5% solution of this detergent solution at 30 minutes of exposure. It was established that the detergent-disinfectant "Argomol" has an effective bactericidal action against the microorganisms being studied. Taking into account the sensitivity of bacteria to the medium, its effective working concentrations are selected. [ABSTRACT FROM AUTHOR]