1. A genome scan for quantitative trait loci associated with body weight at different developmental stages in chickens.
- Author
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Gao, Y., Hu, X. X., Du, Z. Q., Deng, X. M., Huang, Y. H., Fei, J., Feng, J. D., Liu, Z. L., Da, Y., and Li, N.
- Subjects
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GENOMES , *CHICKENS , *BODY weight , *MICROSATELLITE repeats , *GENETIC markers - Abstract
A genome scan to detect quantitative trait loci (QTL) affecting body weight in chickens was conducted on 238 F2 chickens from a reciprocal cross of Silky Fowl and White Plymouth Rock using 125 microsatellite markers covering 23 autosomes and the Z chromosome. Two types of QTL were considered: static QTL (SQ) and developmental QTL (DQ). Static QTL affected the body weight from hatch to time t, and DQ affected the body weight from time t−1 to time t. Six SQ and nine DQ were detected. Of these QTL, four reached a genome-wide significance of 5% or better, with SQ1 and DQ1 being the most significant QTL. Static QTL1 was on chromosome 1 between GCT0006 and MCW0106 and explained 4.05–9.80% of the phenotypic variation in body weights from 3 to 12 weeks of age. At 9, 10 and 11 weeks, the genome-wide significance thresholds of SQ1 were <1%. Developmental QTL1 was located on chromosome 1 between MCW0168 and GCT0006, and explained 2.75% of the phenotypic variation for body weight from week 7 to 8 with a genome-wide significance level <1%. The results suggest that body weight from hatch to time t and developmental growth from time t−1 to time t may involve two different sets of genes or gene actions. [ABSTRACT FROM AUTHOR]
- Published
- 2006
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