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Your search keyword '"Holanda, Rodrigo Assunção"' showing total 2 results
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2 results on '"Holanda, Rodrigo Assunção"'

1. Transdisciplinarity of Vulvovaginal Candidiasis from a Social-Environmental Education Perspective.

Author

Castro Moreira, Paulo Xavier de, Azevedo Furtado, Haryne Lizandrey, Mendes, Thayariane Lira, da Silva, Ângela Nascimento, Holanda, Rodrigo Assunção, and Alves Santos, Julliana Ribeiro

Subjects
*VULVOVAGINAL candidiasis, *NATURAL history, *DISEASE risk factors, *INVASIVE candidiasis
Abstract

Vulvovaginal candidiasis stems from the imbalance between the fungus, woman, and environment. This study aimed to describe the genital infection in an ecological vision to identify the risk factors and socio-environmental prophylactic education measures. This descriptive study employed the qualitative and bibliographical methods used in selected scientific articles. The descriptors used were biomedical model, ecological triad, natural history of the disease, systemic model, vaginal ecosystem, and women's disorders. The holistic approach broadens the knowledge of pathogenesis, characterizes risk factors, and identifies the links in the chain of events where prophylactic measures may be applied. [ABSTRACT FROM AUTHOR]

Published
2018
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2. Isolation and identification of Candida species in patients with orogastric cancer: susceptibility to antifungal drugs, attributes of virulence in vitro and immune response phenotype.

Author

de Sousa, Lourimar Viana Nascimento F., Santos, Vera Lúcia, de Souza Monteiro, Andrea, Dias-Souza, Marcus Vinicíus, Marques, Sirlei Garcia, de Faria, Elaine Speziali, de Oliveira Assunção, Elaine Alves, dos Santos, Simone Gonçalves, Zonis, Juan Moises, de Alvarenga, Daniel Gomes, de Holanda, Rodrigo Assunção, de Sousa, Jaqueline Gontijo, dos Santos, Kênia Valßria, de Resende Stoianoff, Maria Aparecida, Assunção, Elaine Alves de Oliveira, Dos Santos, Kênia Valéria, and Stoianoff, Maria Aparecida de Resende

Subjects
*CANDIDA diagnosis, *CANDIDIASIS treatment, *LIVER cancer, *CANCER invasiveness, *GENETICS of disease susceptibility, *GENETICS, *ANTIFUNGAL agents, *CANDIDA, *CYTOKINES, *MASS spectrometry, *MICROBIAL sensitivity tests, *MOUTH tumors, *OPPORTUNISTIC infections, *ORAL mucosa, *PHENOTYPES, *THRUSH (Mouth disease), *GASTROINTESTINAL tumors, *CASE-control method, *DISEASE complications, *PHARMACODYNAMICS, *DIAGNOSIS, LARYNGEAL tumors
Abstract

Background: Because of the inherent immunosuppression of cancer patients opportunistic infections by Candida spp, occur frequently. This study aimed to identify Candida species in the oral mucosa of 59 patients with orogastric cancer (OGC) and to analyze the immunological phenotype of these patients.Methods: The yeasts were identified by MALDI-TOF mass spectrometry (MS). For all isolates, we performed phospholipases and proteinases assays, in vitro adherence to buccal epithelial cells (BEC), minimum inhibitory concentration of antifungal drugs and determined the cytokine profile by Cytometric Bead Array flow citometry assay.Results: C. albicans was the most prevalent species in OGC patients (51.6 %) and control group (66.7 %). Candida spp. strains isolated from OGC patients exhibited better adherence to BEC (p = 0.05) than did the control group. Phospholipases production by Candida strains from OGC patients was lower (51.6 %) than in the control group (61.9 %). Proteinases were detected in 41.9 % and 4.8 % of the yeasts from OGC patients and control group, respectively. Significant differences were found in the serum of OGC patients compared to the control group for IL-2, IL-10, TNF-α, IFN-γ and IL-17.Conclusions: The results of this work suggest increased virulence of yeasts isolated from OGC patients and, that this may interfere with the immune phenotype. [ABSTRACT FROM AUTHOR]

Published
2016
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