1. Reassessing the management of hypertension: Time to prevent aldosterone‐mediated heart failure.
- Author
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Pitt, Bertram, Brown, Jenifer M., Vaidya, Anand, and Diez, Javier
- Subjects
- *
ALDOSTERONE antagonists , *HEART failure , *TIME management , *CORONARY artery calcification , *ESSENTIAL hypertension , *LEFT ventricular hypertrophy - Abstract
This article discusses the management of hypertension and its relationship to heart failure. Despite current recommendations for hypertension treatment, there is still a significant risk of cardiovascular disease and heart failure among patients with hypertension. The article proposes that excessive production of aldosterone, a hormone, is responsible for cardiac alterations in patients with hypertension and contributes to the risk of heart failure. The authors suggest that mineralocorticoid receptor antagonists (MRAs) should be considered as a first-line treatment in some hypertensive patients to prevent cardiac alterations and reduce the risk of heart failure. The article also highlights the need for further research and clinical trials to test the value of MRAs as a treatment for hypertension. [Extracted from the article]
- Published
- 2024
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