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1. Promising antimicrobial agents designed from natural peptide templates.

Author

Michael Henderson, J. and Lee, Ka Yee C.

Subjects
*ANTI-infective agents, *DRUG design, *PEPTIDES, *CHEMICAL templates, *MICROORGANISMS, *DRUG resistance
Abstract

Highlights: [•] Combating microbes is paramount as many species have developed resistance to antibiotics. [•] Membrane-active molecules preclude resistance development and are promising as future drugs. [•] Physiochemical properties of membrane-active peptides have guided design of synthetic mimics. [•] Rationally-designed polymers can be tuned to be selective antimicrobial agents. [ABSTRACT FROM AUTHOR]

Published
2013
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