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The public enquiry into the mass casualty incident at the Manchester Arena in the UK in which 23 people died and over 1000 were injured, identified the need for timely intramuscular administration of tranexamic acid to trauma patients. Since then, a number of studies and trials have been carried out and UK paramedics are now authorized to give intramuscular tranexamic acid in the pre-hospital setting. In Japan, pre-hospital administration by emergency life-saving technicians is not yet authorized, despite the fact that tranexamic acid was invented by Japanese scientists. In Japan, the need for the pre-hospital administration of tranexamic acid has been raised on several occasions, where a patient died from traumatic bleeding prior to hospital admission. This paper summarizes the evidence on the use of tranexamic acid in patients with traumatic bleeding, including new evidence on the intramuscular route. [ABSTRACT FROM AUTHOR]

Background: Pre‐implantation genetic testing (PGT) has been performed worldwide since it was first used by Handyside et al in the United Kingdom to sex embryos in 1990. Until about 2010, cleavage stage embryo biopsy and fluorescent in situ hybridization (FISH) were mainstream; however, in 2012, blastocyst biopsy (trophectoderm; TE biopsy) became mainstream. In addition, array comparative genomic hybridization (aCGH) was used for analysis and further evolved to next‐generation sequencing (NGS), which is used worldwide. Methods: PGT for reciprocal balanced translocation and Robertsonian translocation (PGT‐SR) was approved in Japan for habitual abortion to reduce pregnancy loss, and since 2008, we have been performing PGT‐SR using cleavage stage embryos and FISH. In 2014, we performed TE biopsy and NGS analysis. Main findings: In this paper, I separately described the details of our methods and clinical results of FISH and NGS. NGS is superior to FISH because it can detect all chromosomes. Conclusion: TE biopsy and NGS, which have recently become mainstream, have stable outcomes, because TE biopsy yields more cells and fewer mosaics than the cleavage stage. As a result, diagnoses are more reliable, resulting in higher pregnancy rates and lower abortion rates. [ABSTRACT FROM AUTHOR]

Objectives. The bibliometric analysis uses the citation count of an article to measure its impact in the scientific community, yet there is still no comprehensive summary of gastric disease researches via bibliometric analysis. We aimed to evaluate the situations and trends of the most cited articles in gastric disease via bibliometric analysis and to provide physicians a practical guide in assessing the most influential articles written on this subject. Methods. The 100 top-cited articles in gastric disease were compiled using Web of Science. The articles selected were evaluated for their number of citations, year of publication, country of origin, type of study, and others. Results. The database had 484,281 articles published between 1965 and 2019. The most cited article received 4,017 citations and the least received 604, with a mean of 1,149 citations. We classified the articles into seven categories: gastric cancer (n = 53), Helicobacter pylori (n = 17), ulcer (n = 7), gastrointestinal stromal tumors (n = 6), gastritis (n = 5), gastric bypass surgery (n = 2), and others (n = 10). Altogether, 69 of the articles were from the USA (n = 41), the UK (n = 17), and Japan (n = 11). Among all the institutions, Royal Perth Hospital led the list with 5 articles. One-quarter of authors owned three or more of these top-cited articles. The 100 papers were published in 33 journals, and most of them were clinical researches (n = 47). Conclusions. Our study provides a historical perspective for the scientific progress of gastric disease, and the articles of significant findings that contributed great impact on the prevention and treatment of gastric disease had been identified. [ABSTRACT FROM AUTHOR]

Using the InCites tool of Thomson Reuters, this study compares normalized citation impact values calculated for China, Japan, France, Germany, United States, and the UK throughout the time period from 1981 to 2010. InCites offers a unique opportunity to study the normalized citation impacts of countries using (i) a long publication window (1981 to 2010), (ii) a differentiation in (broad or more narrow) subject areas, and (iii) allowing for the use of statistical procedures in order to obtain an insightful investigation of national citation trends across the years. Using four broad categories, our results show significantly increasing trends in citation impact values for France, the UK, and especially Germany across the last thirty years in all areas. The citation impact of papers from China is still at a relatively low level (mostly below the world average), but the country follows an increasing trend line. The USA exhibits a stable pattern of high citation impact values across the years. With small impact differences between the publication years, the US trend is increasing in engineering and technology but decreasing in medical and health sciences as well as in agricultural sciences. Similar to the USA, Japan follows increasing as well as decreasing trends in different subject areas, but the variability across the years is small. In most of the years, papers from Japan perform below or approximately at the world average in each subject area. [ABSTRACT FROM AUTHOR]

The global community, from UNESCO to NGOs, is committed to promoting the status of women in science, engineering and technology, despite long-held prejudices and the lack of role models. Previously, when equality was not firmly established as a key issue on international or national agendas, women's colleges played a great role in mentoring female scientists. However, now that a concerted effort has been made by governments, the academic community and the private sector to give women equal opportunities, the raison d'être of women's universities seems to have become lost. This paper argues otherwise, by demonstrating that women's universities in Japan became beneficiaries of government initiatives since the early 2000s to reverse the low ratio of women in scientific research. The paper underscores the importance of the reputation of women's universities embedded in their institutional foundations, by explaining how female scientific communities take shape in different national contexts. England, as a primary example of a neoliberal welfare regime, with its strong emphasis on equality and diversity, promoted its gender equality policy under the auspices of the Department of Trade and Industry. By contrast, with a strong emphasis on family values and the male-breadwinner model, the Japanese government carefully treated the goal of supporting female scientists from the perspective of the equal participation of both men and women rather than that of equality. Following this trend, rather contradictorily, women's universities, with their tradition of fostering a 'good wife, wise mother' image, began to be highlighted as potential gender-free institutions that provided role models and mentoring female scientists. By drawing on the cases of England and Japan, this paper demonstrates how the idea of equality can be framed differently, according to wider institutional contexts, and how this idea impacts on gender policies. [ABSTRACT FROM AUTHOR]

This paper scrutinises organisational change in Japanese and UK universities which are engaged in entrepreneurial activities. The study focuses on recent changes in governance, management, leadership, and funding in these universities. The paper argues there are convergent trends between Japanese and UK universities in terms of increasing entrepreneurial activities, a review of institutional strategies, a review of the organisation, the application of market-oriented institutional policy, links with the industrial sector, the notion of a public financial crisis and changing external environment, strong leadership of the university President or Vice-Chancellor, and the notion of the accountability of the university to society as a whole. However, the application of particular institutional strategies, entrepreneurial culture, and the way in which an institution relates itself to the private sector significantly differs among institutions. The paper suggests that those differences are related to different institutional history and characteristics – including those between national and private universities in Japan, and old and new universities in the UK – as well as different government policies between Japan and the UK. The paper first proposes a theoretical model for the five types of entrepreneurial culture of the institutions. It then examines the model by using case studies: Nottingham Trent University (UK), University of Surrey (UK), University of Tokyo (Japan), and Waseda University (Japan). [ABSTRACT FROM AUTHOR]

The thesis of this paper is that governments of some otherwise enlightened states are increasingly fearful of acknowledging the restraints imposed on them by existing international law. They are also reluctant to enter into new commitments by way of international conventions that would expand the reach of international law. The paper asks whether these fears are based on a true understanding of international law or on some distorted view of it. It will draw comparisons and some contrasts between Australia and the United States in their reactions to a number of recent events as well as to some enduring situations of contemporary relevance. Had time (and the limits of my research) permitted, one might also have examined public attitudes toward international law in China, Japan, and Russia in this context, where similar fears appear to be entertained. France, Germany, Italy, and the United Kingdom, also enlightened states, appear by contrast to belong to a group more dedicated to international law. As Robert Kagan has recently remarked, the experience of two world wars at close quarters, and the formation of the European Union, have made the European countries more dedicated to process, where the United States is more interested in results. [ABSTRACT FROM AUTHOR]

This paper analyses approaches to global education in the United States, the United Kingdom and Japan. The paper begins by looking at movements that preceded global education, such as education for international understanding, development education, multicultural education, and peace education. The rise and fall of these earlier movements is analysed in terms of the interplay between the international and domestic politics of particular countries. To identify the world views which underpinned these pedagogic forms, the author discusses various discontinuities between the period up to the 1990s and thereafter. It is suggested that fresh forms of global education are emerging in — and because of — the changed world of the late 20th and early 21st century. [ABSTRACT FROM AUTHOR]

This paper introduces new models for comparing several social mobility tables that provide various one-degree-of-freedom tests for two mobility tables on substantively meaningful structural components. These components include differences between mobility tables in (1) the strength of off-diagonal associations, (2) the strength of diagonal effects, and (3) the extent of structural mobility. Most of the models in this paper use association models and the Sobel-Hout-Duncan model but are specifically formulated to analyze three-way tables that have either nations or periods as the third dimension. American, British, and Japanese mobility tables are compared. Together, they show that equality of occupational opportunity is larger for the United States than for Great Britain, that Japan's mobility structure is closer to quasi-independence than that of the two other nations, and that Japan's mobility structure became more like that of the United States in 1975 rather than in 1955. These analyses also demonstrate that comparative mobility research based on indexing mobility has strong limitations. [ABSTRACT FROM AUTHOR]

The article presents a scientometric analysis for identifying major specialties of pharmacological research and the countries contributing the highest number of articles in pharmacology. According to the analysis, 1,471 research papers were published from 57 nations. The first nation with 30 percent score of total publications was the U.S. followed by Japan with 13 percent and Great Britain with 8.3 percent. About 37 nations published research papers on cellular and molecular pharmacology.

As of 2008, surrogacy is legal and openly practised in various places; Japan, however, has no regulations or laws regarding surrogacy. This paper reports the situation of surrogacy in Japan and in five other regions (the USA, the UK, Taiwan, Korea and France) to clarify the pros and cons of prohibiting surrogacy, along with the problems and issues relating to surrogacy compensation. Not only in a country such as France that completely prohibits surrogacy within the country, but also in a country such as the UK that allows non-commercial surrogacy, infertile couples travel overseas for the purpose of surrogacy. In addition, some couples might seek underground surrogacy if the government prohibits surrogacy. If an intended parent couple and a surrogate make an agreement among themselves and then a problem occurs, they cannot ask for support from professionals or bring a case to court, as can be observed in South Korea and Taiwan. We also conclude that there is little difference between commercial surrogacy and non-commercial surrogacy in the absence of a clear definition of ‘reasonable expenses.’ In the UK, the law does not allow surrogates to receive compensation. However, in reality, there may be little difference between the amounts paid to surrogates for profit in the US and those paid to surrogates for reasonable expenses in the UK. We conclude that the issue of surrogacy demands further discussion in Japan. [ABSTRACT FROM AUTHOR]

This paper presents a societal level exergy analysis approach developed to analyse transitions in the way that energy is supplied and contributes to economic growth in the UK, the US, Austria and Japan, throughout the last century. We assess changes in exergy and useful work consumption, energy efficiency and related GDP intensity measures of each economy. The novel data provided elucidate certain characteristics of divergence and commonality in the energy transitions studied. The results indicate that in each country the processes of industrialization, urbanisation and electrification are characterised by a marked increase in exergy and useful work supplies and per capita intensities. There is a common and continuous decrease in the exergy intensity of GDP. Moreover for each country studied the trend of increasing useful work intensity of GDP reversed in the early 1970s coincident with the first oil crisis. [Copyright &y& Elsevier]

Myanmar or 'Burma' is a country which has a long history of colonialism by foreign powers. Before Myanmar achieved its independence in 1948, it was ruled by two prominent foreign powers that are Britain and Japan. Both countries had created the political scene of Myanmar. After achieving independence from Britain in 1948, Myanmar became an independent country that practiced the democracy ideology under the ruled of General Aung Sann. However, its democracy system faced problems when a coup d'état happened in 1962. Since that year, the efforts to regain the democracy system in Myanmar faced a lot of obstacles. Thus, this paper will explain the process of democracy development since 1948 until the present days of Myanmar. [ABSTRACT FROM AUTHOR]

This study compares the short-term behaviour of finance directors the UK and in Japan, in the context of their corporate governance systems, using the funding, structure and evaluation of Research and Development (R&D) projects as indicators. The empirical part of the study consists of two questionnaire studies carried out in the UK and Japan. A number of personal interviews were also carried out with UK and Japanese senior finance managers. The results of the study indicate different management behaviour with respect to short-termism in the UK and Japan. There is a statistically significant difference in perceptions between the finance directors of two countries. Managers in both countries appreciate and would like to use long term performance criteria to assess and manage R&D projects. In practice however, Japanese finance directors are much better protected from short-term pressures than their UK counterparts in dealing with most aspects of their management R&D. These differences in behaviour are identified and possible reasons for them are offered in the paper. [ABSTRACT FROM AUTHOR]

This paper examines the relative performance of electricity distribution systems in the UK and Japan between 1985 and 1998 using cost-based benchmarking with data envelopment analysis (DEA) and stochastic frontier analysis (SFA) methods. The results suggest that the productivity gain in the UK electricity distribution has been larger than in the Japanese sector. In particular, productivity growth accelerated during the last years when the UK utilities were operating under tightened revenue caps. It also suggests that efficiency scores are higher for UK utilities. The findings also highlight the advantages of using multiple techniques in comparative analysis and in incentive regulation. [ABSTRACT FROM AUTHOR]

This article examines the origins and potential effects of the liberalising reform agenda in Japanese secondary education in the light of experiences in the UK with policies such as local school management and school choice. The analysis is based on extensive interviews conducted with Japanese policy-makers, school heads and Prefectural administrators in 1997 in Tokyo and Osaka. The research was part of a joint Anglo-Japanese study, supported by the Japanese Embassy in London, and the analysis here highlights issues of national perspective which emerged in the collaboration between English and Japanese researchers observing reforms in each other's countries. The paper argues that the reform agenda in Japan has two strands. These involve both a necessary diversification of curriculum and pedagogic practices, and an administrative shift towards deregulation and school competition which may undermine some of the traditional strengths of Japanese secondary schooling. [ABSTRACT FROM AUTHOR]

Organisations attempt to contribute their share towards fighting the climate crisis by trying to reduce their emission of greenhouse gases effectively towards net zero. An instrument to guide their reduction efforts is internal carbon pricing. Next to choosing the right pricing tool, defining the exact value of an internal carbon price, especially against the background of potential regulatory external carbon prices, and assessing its impact on business units' energy systems poses a challenge for organisations. The academic literature has so far not examined the impact differences of an internal carbon price across different countries, which this paper addresses by using an optimisation model. First, it analyses the energy system cost increase of a real-world facility based on an internal carbon price compared to a potential regulatory carbon price within a country. Second, we evaluate the energy system cost increase based on an internal carbon price across different countries. The results show that with regard to internal carbon prices the additional total system cost compared to potential external carbon prices stays within 9%, 15%, and 59% for Germany, Japan, and the United Kingdom, respectively. The increase in the energy system cost in each country varies between 3% and 93%. For all countries, the cost differences can be reduced by allowing the installation of renewables. The integration of renewables via energy storage and power-to-heat technologies depends on the renewable potentials and the availability of carbon capture and storage. If organisations do not account for these differences, it might raise the disapproval of internal carbon prices within the organisation. [ABSTRACT FROM AUTHOR]

International comparisons of engineering graduate numbers are frequently used as indices of industrial development and measures of the responsiveness of the educational system to industrial requirements. Such comparisons make implicit assumptions about quality by assuming that like institutions or like qualifications are being compared. In this paper the concept of 'best practice' engineering education is derived from engineering manpower reports of German engineering education in order to address issues of both quantity and quality in comparing engineering education in Britain and Japan. Japan is found to have associated engineering education with relatively more prestigious institutions and to have attracted a higher proportion of more able male pupils to broad based engineering education compared to Britain. Yet there are some interesting differences between the model of 'best practice' engineering education based on Germany and Japanese practice, particularly in curricula, which underline the importance of the division of labour between education and employment in the education and training of engineers. Examining the responsiveness of educational systems through propositions derived from a model of 'best practice' rather than through simple output statistics underlines the importance of different patterns of institutional development, the role of the state, educational and occupational selection, and status within the curriculum for understanding the variety of contemporary engineering education. [ABSTRACT FROM AUTHOR]

The serious problem in Japanese education today is the excess of competition. Although that helps the high standard of Japanese education, it also brings about many difficulties for young people. The competition in the school system is, in general, closely related to the competition in society as a whole, especially in the labour market. The structure of the labour market has a strong influence on competition in the school. For example, the British segmented labour market divides the competition by occupation, and it helps the diversified structure of post-compulsory education/training. Meanwhile, in the Japanese labour market, which is characterised by Japanese-style employment, the competition is little divided by occupation, and this helps the unitary structure of competition in the school. Comparing Japan and Britain, this paper will examine the structural causes of the competition in the school system. [ABSTRACT FROM AUTHOR]

Background: As research in family medicine covers varied topics, multiple methodologies such as qualitative research (QR) and mixed methods research (MMR) are crucial. However, we do not know about the difference in the proportion of QR or MMR between Japan, the UK and the US. This knowledge is needed to shape future research within countries with developing primary care such as Japan and other Asian countries. This study aims to describe the use of QR and MMR in Japanese primary care and compare this to the UK and US; then to make informed recommendations for primary care research. Methods: A repeated cross-sectional study (2012–2016) based on the abstracts submitted to the annual conferences of the Japanese Primary Care Association in Japan, the Royal College of General Practitioners in the UK, and the North American Primary Care Research Group in the US and other North American countries. The proportions of QR/MMR among all the posters and paper presentations for each of these three conferences were assessed. Also examined were trends and types of qualitative techniques for all three countries and participants/settings for Japan. Results: There were 1080 abstracts for Japan, 575 for UK and 3614 for US conferences. QR/MMR proportions were 7.5%, 15.1% and 28.1%, respectively. Japan's proportion was lower than that of UK and US (p < 0.001). The proportion was increasing over time for the UK (p = 0.02). Steps for coding and analyses was most popular for Japan, thematic analysis for the UK and grounded theory for the US. Primary care doctors and hospitals were the commonest contexts for Japan. Conclusions: QR and MMR were not as popular in primary care in Japan compared to the UK and the US, whereas their use was increasing in the UK. Approaches, participants and settings may differ among these countries. Education and promotion of QR/MMR and multi-disciplinary collaborations need to be recommended in Japan with developing primary care. [ABSTRACT FROM AUTHOR]

We examine empirically whether asset prices and exchange rates may be admitted into a standard interest rate rule, using data for the United States, the United Kingdom, and Japan since 1979. Asset prices and exchange rates can be employed as information variables for a standard "Taylor-type" rule or as arguments in an augmented interest rate rule. Our empirical evidence, based on measures of the output gap proxied by marginal cost calculations, suggests that monetary policy- makers may use asset prices and exchange rates not only as part of their information set for setting interest rates, but also to set interest rates to offset deviations of asset prices or exchange rates from their equilibrium levels. These results are open to several alternative interpretations. [ABSTRACT FROM AUTHOR]