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We study symmetric periodic orbits near collision in a nonautonomous restricted planar four-body problem. The restricted problem consists of a massless particle moving under the gravitational influence due to three bodies with the same positive mass (the primaries), following the figure-eight choreography. We use regularized coordinates, in order to deal numerically with motions near collision between the massless particle and one of the primaries. By means of reversing symmetries, we characterize the symmetric periodic orbits near collision. The initial conditions for these orbits were computed by solving numerically some boundary value problems. We explain theoretically, and confirm numerically, how different parts of the diagram of initial conditions are related due to the symmetry of the figure-eight choreography. [ABSTRACT FROM AUTHOR]

Business Processes (BPs) are commonly used by organizations to describe their goals. However, the existent decentralization found in many organizations forces them to build such BPs by coordinating distributed and fragmented BPs. Within this context, microservices arise as a very interesting and convenient way to address the implementation of such processes due to their low coupling characteristic. In this case, the coordination of such fragmented BPs is usually achieved by means of event-based choreographies. One of the main challenges to be faced by choreographies is their evolution due to the complexity that introduces the need of integrating changes among autonomous and independent partners. We face the challenge of evolving a microservice composition that is globally defined in a BPMN model but executed through a choreography of BPMN fragments. We introduce a protocol to manage the propagation of a change done by one microservice to be integrated into both the BPMN fragments of the rest of the microservices and the global BPMN model. This protocol also supports the negotiation among participants and the automatic suggestion of model adaptations to maintain the functional integrity of the composition. These suggestions are supported by a catalogue of adaptation rules that precisely characterize every possible change and propose actions to be considered by the affected microservices. All the evolution process is done at the modelling level, without managing hard-coded implementations. We have developed specific tools to facilitate the practical adoption of this protocol, and we have validated our work in an experiment with users. We can conclude that the proposed approach is effective to evolve microservice compositions implemented as event-based choreography of BPMN fragments from the local perspective of one partner. [ABSTRACT FROM AUTHOR]

Hybrid figures serve as an important component of artistic swimming, however, no prior research has investigated objective indicators for predicting total scores in competition. This study aimed to identify significance of hybrid figure (HF) elements in predicting total scores in artistic swimming competitions and compare these variables between the Beijing team trials and international official competitions. Eight HF variables were measured in the videos from the international artistic swimming competitions, with calibration and measurement of the variables leg height index and leg angle deviation being performed by means of Kinovea. Multiple linear regression was conducted to predict the total scores based on these variables investigated for the international teams, which showed 5 significant predictors including movement frequency, leg height index, leg angle deviation, mean pattern duration, and rotation frequency. Wilcoxon signed-rank test was used to determine the differences in the variables between the Beijing team and the international teams (top 5), which showed significant difference on movement frequency, leg angle deviation, leg height index and total score. When designing hybrid figures choreography of team free routine in artistic swimming, coaches should prioritize appropriate movement frequency, pattern changes and rotations over excessively long durations. Overly complex HF choreography may lead to a decline on performance in artistic swimming competition. [ABSTRACT FROM AUTHOR]

The dynamics of DNA in the cell nucleus plays a role in cellular processes and fates but the interplay of DNA mobility with the hierarchical levels of DNA organization is still underexplored. Here, we made use of DNA replication to directly label genomic DNA in an unbiased genome-wide manner. This was followed by live-cell time-lapse microscopy of the labeled DNA combining imaging at different resolutions levels simultaneously and allowing one to trace DNA motion across organization levels within the same cells. Quantification of the labeled DNA segments at different microscopic resolution levels revealed sizes comparable to the ones reported for DNA loops using 3D super-resolution microscopy, topologically associated domains (TAD) using 3D widefield microscopy, and also entire chromosomes. By employing advanced chromatin tracking and image registration, we discovered that DNA exhibited higher mobility at the individual loop level compared to the TAD level and even less at the chromosome level. Additionally, our findings indicate that chromatin movement, regardless of the resolution, slowed down during the S phase of the cell cycle compared to the G1/G2 phases. Furthermore, we found that a fraction of DNA loops and TADs exhibited directed movement with the majority depicting constrained movement. Our data also indicated spatial mobility differences with DNA loops and TADs at the nuclear periphery and the nuclear interior exhibiting lower velocity and radius of gyration than the intermediate locations. On the basis of these insights, we propose that there is a link between DNA mobility and its organizational structure including spatial distribution, which impacts cellular processes. [ABSTRACT FROM AUTHOR]

Service choreographies are a versatile approach for building service-based distributed systems. Many approaches can be found in the literature tackling different aspects of service choreographies, such as choreography realizability and conformance checking, distributed coordination, formal choreographic languages, and scalability. As of today, choreography scalability has not been specifically addressed through approaches that also consider coordination issues while still decoupling these two related aspects. Scalability is one of the most important properties to be considered when building distributed systems. It enhances the user-perceived performances and influences the overall dependability of the system. In particular, load scalability allows distributed service-oriented systems to effectively handle varying loads without suffering performance degradation. In this direction, microservice-based systems are able to scale thanks to the possibility of replicating those microservices exposed to growing loads, distributing their workload among different instances. By leveraging on our experience in coordinating service choreographies, in this paper, we propose a layered architectural style that allows to realize scalable microservice-oriented choreographies. The architecture integrates a fully-distributed coordination layer capable of ensuring the correct interactions and a load-balancing layer that allows to balance of coordinated requests. We discuss the properties of the proposed architectural style and evaluate its benefits on user-perceived performances. [ABSTRACT FROM AUTHOR]

The Janus kinases (JAK) are crucial targets in drug development for several diseases. However, accounting for the impact of possible structural rearrangements on the binding of different kinase inhibitors is complicated by the extensive conformational variability of their catalytic kinase domain (KD). The dynamic KD contains mainly four prominent mobile structural motifs: the phosphate-binding loop (P-loop), the αC-helix within the N-lobe, the Asp-Phe-Gly (DFG) motif, and the activation loop (A-loop) within the C-lobe. These distinct structural orientations imply a complex signal transmission path for regulating the A-loop’s flexibility and conformational preference for optimal JAK function. Nevertheless, the precise dynamical features of the JAK induced by different types of inhibitors still remain elusive. We performed comparative, microsecond-long, Gaussian accelerated molecular dynamics simulations in triplicate of three phosphorylated JAK2 systems: the KD alone, type-I ATP-competitive inhibitor (CI) bound KD in the catalytically active DFG-in conformation, and the type-II inhibitor (AI) bound KD in the catalytically inactive DFG-out conformation. Our results indicate significant conformational variations observed in the A-loop and αC helix motions upon inhibitor binding. Our studies also reveal that the DFG-out inactive conformation is characterized by the closed A-loop rearrangement, open catalytic cleft of N and C-lobe, the outward movement of the αC helix, and open P-loop states. Moreover, the outward positioning of the αC helix impacts the hallmark salt bridge formation between Lys882 and Glu898 in an inactive conformation. Finally, we compared their ligand binding poses and free energy by the MM/PBSA approach. The free energy calculations suggested that the AI’s binding affinity is higher than CI against JAK2 due to an increased favorable contribution from the total non-polar interactions and the involvement of the αC helix. Overall, our study provides the structural and energetic insights crucial for developing more promising type I/II JAK2 inhibitors for treating JAK-related diseases. [ABSTRACT FROM AUTHOR]

The intelligibility of a performance of improvised dance does not reside in the rehearsed execution of a pre-existing script, nor does it result from a sustained verbal interaction between the dancers. Many aspects of the speechless performance obviously play an important role in the achieved intelligibility of the dance: a dancer is seen moving on and from a ground, on a stage, in a space delimited by walls, illuminated by spotlights, sounded by music, in front of an audience. And of course with other dancers, whose joint gestures and moves give shape to a choreography by providing pace, rhythm and sequences, thereby constituting a narrative or fragments thereof. This paper addresses the manufacture of this witnessable order, by presenting some results of an ethnographic inquiry. The investigation will be focused on how, in an improvised duet, each dancer interacts with the other, and more specifically how she or he positions her- or himself in relation to the other, from distance to proximity and touch. This work of distance management is the dance, whose choreographic accountability is produced and structured by dancers staying at a distance, getting closer and touching each other. The analysis shows that distance management is oriented to as relevant by the dancers and that it has consequences on their improvised duet. It is also what makes their performance analyzable by distant observers. [ABSTRACT FROM AUTHOR]

A humanoid robot named 'Sophia' has sparked controversy since it has been given citizenship and has done media performances all over the world. The company that made the robot, Hanson Robotics, has touted Sophia as the future of artificial intelligence (AI). Robot scientists and philosophers have been more pessimistic about its capabilities, describing Sophia as a sophisticated puppet or chatbot. Looking behind the rhetoric about Sophia's citizenship and intelligence and going beyond recent discussions on the moral status or legal personhood of AI robots, we analyse the performativity of Sophia from the perspective of what we call 'political choreography': drawing on phenomenological approaches to performance-oriented philosophy of technology. This paper proposes to interpret and discuss the world tour of Sophia as a political choreography that boosts the rise of the social robot market, rather than a statement about robot citizenship or artificial intelligence. We argue that the media performances of the Sophia robot were choreographed to advance specific political interests. We illustrate our philosophical discussion with media material of the Sophia performance, which helps us to explore the mechanisms through which the media spectacle functions hand in hand with advancing the economic interests of technology industries and their governmental promotors. Using a phenomenological approach and attending to the movement of robots, we also criticize the notion of 'embodied intelligence' used in the context of social robotics and AI. In this way, we put the discussions about the robot's rights or citizenship in the context of AI politics and economics. [ABSTRACT FROM AUTHOR]

The aim of this paper is to study the motion of a 2 + n -body problem where two equal masses are assumed to be fixed. We assume that the value of each fixed mass is equal to M > 0 and the remaining n moving particles have equal masses m > 0 . According to Newton’s second law and the universal gravitation law, the n particles move under the interaction of each other and the affection of the two fixed particles. Also, this motion has a natural variational structure. Under the simple choreography constraint, we show that the Lagrangian action functional attains its absolute minimum on a uniform circular motion. [ABSTRACT FROM AUTHOR]

In recent years, automatic music-driven choreography has become a highly challenging problem to be solved. In this paper, we propose a music-driven choreography system based on conditional generative adversarial networks. First, a dataset MF-DS integrating MFCC features and Dancing Skeletons extracted from Japanese dancing videos is built by ourselves for the study. The MFCC features are extracted based on music beats, and the dancing skeletons are detected based on the image frames of a video. In the training, we use a generative adversarial network to train the music-driven choreography system. The generator integrates residual blocks into fractionally stridden convolution, and the discriminator involves conventional CNNs. Two indicators called beat loss values and choreography diversity values are proposed to evaluate three learning models in the experiments. Finally, we validate that the three models with the best epochs have the near-zero loss for the generator and discriminator, thereby generating stable skeletons and presenting choreography diversity. [ABSTRACT FROM AUTHOR]

Team training and interprofessional training have recently emerged as critical new simulations that enhance performance by coordinating communication, leadership, professional, and, to a certain extent, technical skills. In describing these new training tools, the term choreography has been loosely used, but no critical appraisal of the role of the science of choreography has been applied to a surgical procedure. By analogy, the surgical team, including anesthetists, surgeons, nurses, and technicians, constitutes a complete ensemble, whose physical actions and interactions constitute the 'performance of surgery.' There are very specific 'elements' (tools) that are basic to choreography, such as space, timing, rhythm, energy, cues, transitions, and especially rehearsal. This review explores whether such a metaphor is appropriate and the possibility of applying the science of choreography to the surgical team in the operating theater. [ABSTRACT FROM AUTHOR]

This paper deals with the existence of N vortex patches located at the vertex of a regular polygon with N sides that rotate around the center of the polygon at a constant angular velocity. That is done for Euler and (SQG) β equations, with β ∈ (0 , 1) , but may be also extended to more general models. The idea is the desingularization of the Thomsom polygon for the N point vortex system, that is, N point vortices located at the vertex of a regular polygon with N sides. The proof is based on the study of the contour dynamics equation combined with the application of the infinite-dimensional implicit function theorem and the well-chosen of the function spaces. [ABSTRACT FROM AUTHOR]

Reversible DNA methylation is a fundamental epigenetic manipulator of the genomic information in eukaryotes. DNA demethylation plays a very significant role during embryonic development and stands out for its contribution in molecular reconfiguration during cellular differentiation for determining stem cell fate. DNA demethylation arbitrated extensive make-over of the genome via reprogramming in the early embryo results in stem cell plasticity followed by commitment to the principal cell lineages. This article attempts to highlight the sequential phases and hierarchical mode of DNA demethylation events during enactment of the molecular strategy for developmental transition. A comprehensive knowledge regarding the pattern of DNA demethylation during embryogenesis and organogenesis and study of the related lacunae will offer exciting avenues for future biomedical research and stem cell-based regenerative therapy. [ABSTRACT FROM AUTHOR]

In this article we estimate mutual distances of simple choreographic solutions for the Newtonian three-body problem. Explicit formulas will be proved and our applications include the famous figure-8 orbit. [ABSTRACT FROM AUTHOR]

Eukaryotic complexity and thus their ability to respond to diverse cues are largely driven by varying expression of gene products, qualitatively and quantitatively. Protein adducts in the form of post-translational modifications, most of which are derived from metabolic intermediates, allow fine tuning of gene expression at multiple levels. With the advent of high-throughput and high-resolution mapping technologies there has been an explosion in terms of the kind of modifications on chromatin and other factors that govern gene expression. Moreover, even the classical notion of acetylation and methylation dependent regulation of transcription is now known to be intrinsically coupled to biochemical pathways, which were otherwise regarded as ‘mundane’. Here we have not only reviewed some of the recent literature but also have highlighted the dependence of gene regulatory mechanisms on metabolic inputs, both direct and indirect. We have also tried to bring forth some of the open questions, and how our understanding of gene expression has changed dramatically over the last few years, which has largely become metabolism centric. Finally, metabolic regulation of epigenome and gene expression has gained much traction due to the increased incidence of lifestyle and age-related diseases. [ABSTRACT FROM AUTHOR]

Recently, several educational game platforms have been proposed in the literature for choreographic training. However, their main limitation is that they fail to provide a quantitative assessment framework of a performing choreography against a groundtruth one. In this paper, we address this issue by proposing a machine learning framework exploiting deep learning paradigms. In particular, we introduce a long short-term memory network with the main capability of analyzing 3D captured skeleton feature joints of a dancer into predefined choreographic postures. This pose identification procedure is capable of providing a detailed (fine) evaluation score of a performing dance. In addition, the paper proposes a choreographic summarization architecture based on sparse modeling representative selection (SMRS) in order to abstractly represent the performing choreography through a set of key choreographic primitives. We have modified the SMRS algorithm in a way to extract hierarchies of key representatives. Choreographic summarization provides an efficient tool for a coarse quantitative evaluation of a dance. Moreover, hierarchical representation scheme allows for a scalable assessment of a choreography. The serious game platform supports advanced visualization toolkits using Labanotation in order to deliver the performing sequence in a formal documentation. [ABSTRACT FROM AUTHOR]

This paper studies the dynamic multi-path environment, mainly solves the problems of poor data transmission and high image recognition error in the existing system, and designs and develops a moving image monitoring and tracking tool, which can effectively complete the tasks of illumination balance, target recognition and target tracking. In addition, according to the teaching mode and actual situation of dance choreography in colleges and universities, the actual demand of teaching dance choreography in colleges and universities is analyzed, the teaching system of dance choreography is designed, and the system is tested in strict accordance with the design and development ideas of software engineering. The results show that the choreography teaching system proposed in this paper has certain advantages, which can effectively deal with different problems in the dynamic multipath environment, and also provide effective teaching solutions for choreography teaching in universities. The development and innovation of choreography teaching system can provide reference for other similar fields. [ABSTRACT FROM AUTHOR]

Service-based applications are based on modern architectures that require careful design of interfaces and protocols to allow smooth integration of service components. These design artifacts are not only useful for implementation, but could also be used for the derivation of integration tests. In order to be applied in these different activities of the development process, they have to conform to existing requirements and other specifications at different architectural levels. In addition, their internal consistency has to be ensured. In this paper, we present an approach to service integration based on a domain-specific language for service choreographies. We first explain the motivation for our work by defining the industrial context that led to the definition of a domain-specific choreography language, called message choreography modeling (MCM). We then provide syntax and semantics for MCM, together with suitable methods for ensuring its consistency. Finally, we report on our experience in applying the described language in practice. [ABSTRACT FROM AUTHOR]

Choreographies are periodic orbits in which all bodies move on the same trajectory with equal time delay. The best known three-body choreography is figure-eight orbit. Here we introduce a search method specialized for choreographies and present three new orbits with vanishing angular momentum that are the first clear examples of choreographies that cannot be described as k-th powers of the figure-eight solution, according to the topological classification of orbits. We have also found 17 new 'powers of the eight' choreographies. According to our numerical computation, one of two distinct $$k=7$$ choreographies is linearly stable. [ABSTRACT FROM AUTHOR]

Enterprises reach out for collaborations with other organizations in order to offer complex products and services to the market. Such collaboration and coordination between different organizations, for a good share, is facilitated by information technology. The BPMN process choreography is a modeling language for specifying the exchange of information and services between different organizations at the business level. Recently, there is a surging use of the REST architectural style for the provisioning of services on the web, but few systematic engineering approach to design their collaboration. In this paper, we address this gap in a comprehensive way by defining a semi-automatic method for the derivation of RESTful choreographies from process choreographies. The method is based on natural language analysis techniques to derive interactions from the textual information in process choreographies. The proposed method is evaluated in terms of effectiveness resulting in the intervention of a web engineer in only about 10% of all generated RESTful interactions. [ABSTRACT FROM AUTHOR]

Current Internet of Things (IoT) development requires service distribution over Wireless Sensor and Actor Networks (WSAN) to deal with the drastic increasing of network management complexity. Because of the specific constraints of WSAN, some limitations can be observed in centralized approaches. Multi-hop communication used by WSAN introduces transmission latency, packet errors, router congestion and security issues. As it uses local services, a model of decentralized services avoids long path communications between nodes and applications. But the two main issues are then to design (1) the composition of such services and to map (2) them over the WSAN. This contribution proposes a model for decentralized services based on Resource Oriented Architecture in which their communications are designed thanks to an adaptation of Petri Network (1). In addition, the problem of decentralized service mapping and its deployment over a WSAN is successfully resumed by a Pseudo-Boolean Optimization in order to minimize network communication load (2). These contributions are presented using a proposed EMMA middleware as unifying thread. [ABSTRACT FROM AUTHOR]

In Choreographic Programming, a distributed system is programmed by giving a choreography, a global description of its interactions, instead of separately specifying the behaviour of each of its processes. Process implementations in terms of a distributed language can then be automatically projected from a choreography. We present Linear Compositional Choreographies (LCC), a proof theory for reasoning about programs that modularly combine choreographies with processes. Using LCC, we logically reconstruct a semantics and a projection procedure for programs. For the first time, we also obtain a procedure for extracting choreographies from process terms. [ABSTRACT FROM AUTHOR]

Cell movements are essential for animal development and homeostasis but also contribute to disease. Moving cells typically extend protrusions towards a chemoattractant, adhere to the substrate, contract and detach at the rear. It is less clear how cells that migrate in interconnected groups in vivo coordinate their behaviour and navigate through natural environments. The border cells of the Drosophila melanogaster ovary have emerged as an excellent model for the study of collective cell movement, aided by innovative genetic, live imaging, and photomanipulation techniques. Here we provide an overview of the molecular choreography of border cells and its more general implications. [ABSTRACT FROM AUTHOR]

Liberation of damage-associated molecular patterns (DAMPs) following tissue injury and necrotic cell death leads to the induction of sterile inflammation. A hallmark of acute inflammation is the recruitment of neutrophils to injured tissues. This review focuses on the journey of neutrophils to sites of sterile inflammation and the cellular and molecular mechanisms that choreograph this complex voyage. We review the pathway of leukocyte recruitment, with emphasis on recent additions to our understanding of intravascular neutrophil migration. The contributions of various tissue-resident sentinel cell populations to the detection of danger signals (DAMPs) and coordination of neutrophil recruitment and migration are discussed. In addition, we highlight recent data on the control of neutrophil chemotaxis towards sites of sterile inflammation, including new insight into the temporal and spatial regulation of chemoattractant guidance signals that direct cell migration. Given that inappropriate neutrophilic inflammation is a cornerstone in the pathogenesis of many diseases, a complete understanding of the choreography of neutrophil recruitment to sites of sterile inflammation may uncover new avenues for therapeutic interventions to treat inflammatory pathologies. [ABSTRACT FROM AUTHOR]

Germinal centers (GC) are large aggregates of proliferating B lymphocytes within follicles of lymphoid tissue that form during adaptive immune responses. GCs are the source of long-lived B cells that form the basis for pathogen-specific lifelong B cell immunity. The complex architecture of these structures includes subdomains that differ significantly in their stromal cell and T lymphocyte subset composition. In part due to their structural complexity and potential to generate some lymphomas, much interest and many theories about GC dynamics have emerged. Here, we review recent research employing in vivo imaging that has begun to untangle some of the mysteries. [ABSTRACT FROM AUTHOR]

Store-operated calcium channels (SOCs) serve essential functions from secretion and motility to gene expression and cell growth. A fundamental mystery is how the depletion of Ca2+ from the endoplasmic reticulum (ER) activates Ca2+ entry through SOCs in the plasma membrane. Recent studies using genetic approaches have identified genes encoding the ER Ca2+ sensor and a prototypic SOC, the Ca2+-release-activated Ca2+ (CRAC) channel. New findings reveal a unique mechanism for channel activation, in which the CRAC channel and its sensor migrate independently to closely apposed sites of interaction in the ER and the plasma membrane. [ABSTRACT FROM AUTHOR]

Discusses the portrayal of the life of novelist Marquis de Sade in the motion picture 'Quills,' directed by Philip Kaufman. Censorship of de Sade's works; Neurotic effects of persistent repression of desire; Sade's reaction to the symbol of crucifix in his final moments.

Alphaviruses are (re-)emerging arboviruses of public health concern. The nsP3 gene product is one of the key players during viral replication. NsP3 comprises three domains: a macro domain, a zinc-binding domain and a hypervariable region. The macro domain is essential at both early and late stages of the replication cycle through ADP-ribose (ADPr) binding and de-ADP-ribosylation of host proteins. However, both its specific role and the precise molecular mechanism of de-ADP-ribosylation across specific viral families remains to be elucidated. Here we investigate by X-ray crystallography the mechanism of ADPr reactivity in the active site of Getah virus macro domain, which displays a peculiar substitution of one of the conserved residues in the catalytic loop. ADPr adopts distinct poses including a covalent bond between the C′′1 of the ADPr and a conserved Togaviridae-specific cysteine. These different poses observed for ADPr may represent snapshots of the de-ADP-ribosylation mechanism, highlighting residues to be further characterised. [ABSTRACT FROM AUTHOR]

This article discusses the potential of regulatory T cells in suppressing immune responses in vivo. Regulatory T cells may act on prime T cells by inducing the secretion of suppressive cytokines or the decrease of tryptophan metabolism. Alternatively, suppression may involve direct contact between regulatory T cells and effector T cells. Regulatory T cells may also have the ability to kill activated T cells in a perforin-dependent way. Finally, cytokines such as interleukin 10 or transforming growth factor, produced by regulatory T cells or other cells, may exert local suppression.

The article discusses the movement of proteins just under the cell surface. Definition of the term endocytosis; Introduction of electron microscopy that provides information on clathrin-coated vesicles and half-formed pockets in plasma membrane; Examination of endocytosis in the yeast saccharomyces cerevisiae.

Animals respond to chemical stress with an array of gene families and pathways termed 'chemical defensome'. In arthropods, despite many defensome genes have been detected, how their activation is arranged during toxic exposure remains poorly understood. Here, we sequenced the transcriptome of Anopheles stephensi larvae exposed for six, 24 and 48 hours to the LD50 dose of the insecticide permethrin to monitor transcriptional changes of defensome genes across time. A total of 177 genes involved in insecticide defense were differentially expressed (DE) in at least one time-point, including genes encoding for Phase 0, I, II, III and antioxidant enzymes and for Heat Shock and Cuticular Proteins. Three major patterns emerged throughout time. First, most of DE genes were down-regulated at all time-points, suggesting a reallocation of energetic resources during insecticide stress. Second, single genes and clusters of genes turn off and on from six to 48 hours of treatment, showing a modulated response across time. Third, the number of up-regulated genes peaked at six hours and then decreased during exposure. Our results give a first picture of how defensome gene families respond against toxicants and provide a valuable resource for understanding how defensome genes work together during insecticide stress. [ABSTRACT FROM AUTHOR]

The cost savings introduced by Web services through code reuse and integration opportunities have motivated many businesses to develop Web APIs, with ever increasing numbers opting for the REST architectural style. RESTful Web APIs are decomposed in multiple resources, which the client can manipulate through HTTP interactions with well-defined semantics. Getting the resource in the desired state might require multiple client-server interactions, what we define as a RESTful conversation. RESTful conversations are dynamically guided by hypermedia controls, such as links. Thus, when deciding whether and how to use a given RESTful service, the client might not be aware of all the interactions which are necessary to achieve its goal. This is because existing documentation of RESTful APIs describes the static structure of the interface, exposing low-level HTTP details, while little attention has been paid to conceptual, high-level, modeling of the dynamics of RESTful conversations. Low-level HTTP details can be abstracted from during the design phase of the API, or when deciding which API to use. We argue that, in these situations, visual models of the required client-server interactions might increase developers’ efficiency and facilitate their understanding. Thus, to capture all possible interaction sequences in a given RESTful conversation, we propose RESTalk, an extension to the BPMN Choreography diagrams to render them more concise and yet sufficiently expressive in the specific REST domain. We also report on the results obtained from an exploratory survey we have conducted to assess the maturity of the field for a domain-specific language and to obtain feedback for future improvements of RESTalk. [ABSTRACT FROM AUTHOR]

The physical demands placed on dancers from current choreography and performance schedules make their physiology and fitness just as important as skill development. However, even at the height of their professional careers, dancers' aerobic power, muscular strength, muscular balance, bone and joint integrity are the ‘Achilles heels’ of the dance-only selection and training system. This partly reflects the unfounded view, shared by sections of the dance world, that any exercise training that is not directly related to dance would diminish dancers' aesthetic appearances. Given that performing dance itself elicits only limited stimuli for positive fitness adaptations, it is not surprising that professional dancers often demonstrate values similar to those obtained from healthy sedentary individuals of comparable age in key fitness-related parameters. In contrast, recent data on male and female dancers revealed that supplementary exercise training can lead to improvements of such fitness parameters and reduce incidents of dance injuries, without interfering with key artistic and aesthetic requirements. It seems, however, that strict selection and training regimens have succeeded in transforming dance to an activity practised by individuals who have selectively developed different flexibility characteristics compared with athletes. Bodyweight targets are normally met by low energy intakes, with female dance students and professional ballerinas reported to consume below 70% and 80% of the recommended daily allowance of energy intake, respectively, while the female athlete ‘triad’ of disordered eating, amenorrhoea and osteoporosis is now well recognised and is seen just as commonly in dancers. An awareness of these factors will assist dancers and their teachers to improve training techniques, to employ effective injury prevention strategies and to determine better physical conditioning. However, any change in the traditional training regimes must be approached cautiously to ensure that the aesthetic content of the dance is not affected by new training techniques. Since physiological aspects of performing dance have been viewed primarily in the context of ballet, further scientific research on all forms of dance is required. [ABSTRACT FROM AUTHOR]

We present the results of a numerical search for periodic orbits with zero angular momentum in the Newtonian planar three-body problem with equal masses focused on a (narrow) search window bracketing the figure-eight initial conditions. We found eleven solutions that can be described as some power of the 'figure-eight' solution in the sense of the topological classification method. One of these solutions, with the seventh power of the 'figure-eight', is a choreography. We show numerical evidence of its stability. [ABSTRACT FROM AUTHOR]

The world is inherently meaningful for us, i.e. we perceive the world in terms of what we can do with it, and by physically interacting with it we access this meaning and express the meaning. We believe that this is the core reason and foundation for turning to movement-based interaction. ‘Interaction creates meaning’ does not only hold for users during interaction but also for designers when generating ideas and developing concepts. Therefore, we postulate that if one truly likes to design for movement-based interaction, one has to be or become an expert in movement, not just theoretically, by imagination or on paper, but by doing and experiencing while designing. In order to do so, we believe that designers need design tools, techniques, knowledge, awareness and skills that support their search for expressive, rich behaviour. Our search for this support resulted in several methods, tools and knowledge that help designers exploring, visualising and reflecting on interactions. Our developed methods and tools such as the Design Movement approach with its choreography of interaction, gestural design tools, interactive installations and interactive tangible sketching, have not only supported and inspired designers to design for movement-based interaction, but also resulted in surprising, fresh designs in comparison with the limited scope of rather uniform and traditional electronic consumer products. This paper discusses the possibilities and limitations of our approach. [ABSTRACT FROM AUTHOR]

Abstract  We have developed an automatic composition system for ballet choreographies by using 3DCG animation. Our goal is to develop useful tools in dance education such as a creation-support system for ballet teachers and a self-study system for students. The algorithm for automatic composition was integrated to create utilitarian choreographies. As a result of an evaluation test, we verified that the created choreographies had a possibility to be used in the actual lessons. This system is valuable for online virtual dance experimentation and exploration by teachers and choreographers involved in creative practices, improvisation, creative movement, or dance composition. [ABSTRACT FROM AUTHOR]

This paper first presents CycleDance, a novel dance style transfer system that transforms an existing motion clip in one dance style into a motion clip in another dance style while attempting to preserve the motion context of the dance. CycleDance extends existing CycleGAN architectures with multimodal transformer encoders to account for the music context. We adopt a sequence length-based curriculum learning strategy to stabilize training. Our approach captures rich and long-term intra-relations between motion frames, which is a common challenge in motion transfer and synthesis work. Building upon CycleDance, we further propose StarDance, which enables many-to-many mappings across different styles using a single generator network. Additionally, we introduce new metrics for gauging transfer strength and content preservation in the context of dance movements. To evaluate the performance of our approach, we perform an extensive ablation study and a human study with 30 participants, each with 5 or more years of dance experience. Our experimental results show that our approach can generate realistic movements with the target style, outperforming the baseline CycleGAN and its variants on naturalness, transfer strength, and content preservation. Our proposed approach has potential applications in choreography, gaming, animation, and tool development for artistic and scientific innovations in the field of dance. [ABSTRACT FROM AUTHOR]

Message-based systems are usually distributed in nature, and distributed components collaborate via asynchronous message passing. In some cases, particular ordering among the messages may lead to violation of the desired properties such as data confidentiality. Due to the absence of a global clock and usage of off-the-shelf components, such unwanted orderings can be neither statically inspected nor verified by revising their codes at design time. We propose a choreography-based runtime verification algorithm that given an automata-based specification of unwanted message sequences detects the formation of the unwanted sequences. Our algorithm is fully decentralized in the sense that each component is equipped with a monitor, as opposed to having a centralized monitor, and also the specification of the unwanted sequences is decomposed among monitors. In this way, when a component sends a message, its monitor inspects if there is a possibility for the formation of unwanted message sequences. As there is no global clock in message-based systems, monitors cannot determine the exact ordering among messages. In such cases, they decide conservatively and declare a sequence formation even if that sequence has not been formed. We prevent such conservative declarations in our algorithm as much as possible and then characterize its operational guarantees. We evaluate the efficiency and scalability of our algorithm in terms of the communication overhead, the memory consumption, and the latency of the result declaration through simulation. [ABSTRACT FROM AUTHOR]

The present work studies the continuation class of the regular n-gon solution of the n-body problem. For odd numbers of bodies between n = 3 and n = 15 , we apply one parameter numerical continuation algorithms to the energy/frequency variable and find that the figure eight choreography can be reached starting from the regular n-gon. The continuation leaves the plane of the n-gon and passes through families of spatial choreographies with the topology of torus knots. Numerical continuation out of the n-gon solution is complicated by the fact that the kernel of the linearization there is high dimensional. Our work exploits a symmetrized version of the problem which admits dense sets of choreography solutions and which can be written as a delay differential equation in terms of one of the bodies. This symmetrized setup simplifies the problem in several ways. On the one hand, the direction of the kernel is determined automatically by the symmetry. On the other hand, the set of possible bifurcations is reduced and the n-gon continues to the eight after a single symmetry breaking bifurcation. Based on the calculations presented here, we conjecture that the n-gon and the eight are in the same continuation class for all odd numbers of bodies. [ABSTRACT FROM AUTHOR]

Dancing is inevitably associated with kinesthetics of the body, including movements, gestures, poses, jumps, turnings, transferring body weight, etcetera. Thus, dance is a manifestation of an amateur or the skilled behavior of a fully trained athletic performance. At the same time, dance is accompanied by emotions as an effect of expression, narration of choreography. Dance is also pre-planned and designed to produce numerous styles and techniques. It is a unique type of improvisation. However, in certain situations, styles and techniques that will be discussed below, the dancing body can bring the dancer closer to his/her emotionality and even spirituality. Thus, the aim of this philosophical exploration is to analyze the impact of spirituality on dance performance. [ABSTRACT FROM AUTHOR]

When meeting someone new, the first impression is often influenced by someone’s physical appearance and other types of prejudice. In this paper, we present TouchMeDare, an interactive canvas, which aims to provide an experience when meeting new people, while preventing visual prejudice and lowering potential thresholds. The focus of the designed experience was to stimulate people to get acquainted through the interactive canvas. TouchMeDare consists of a flexible, opaque canvas, which plays music when touched simultaneously from both sides. Dynamic variation of this bodily contact is reflected through real-time adaptations of the musical compositions. Two redesigns were qualitatively and quantitatively evaluated and a final version was placed in the Lowlands Festival as a case study. Evaluation results showed that some explanation was needed for the initial interaction with the installation. On the other hand, after this initial unfamiliarity passed, results showed that making bodily contact through the installation did help people to get acquainted with each other and increased their social interaction. [ABSTRACT FROM AUTHOR]

Collaborative and distributed engineering Web services are emerging as a viable alternative to the traditional design and engineering process automation. Existing approaches have limitations in supporting long-running engineering transactions, automatic engineering process orchestration and choreography, synchronous and asynchronous conversation, and geometric abstraction for transmission and sharing. In this paper, we present a process-centric engineering Web services framework to overcome these limitations by utilizing BPEL-based (business process execution language) process templates and coordination broker-based conversation support. This paper also discusses the synchronization of engineering Web services, which can be either peer-centric or process-centric to support long-running engineering transactions and conversation. The process orchestration and choreography broker works as a service dispatching and aggregation agent for executing process templates, which enables the individual activity of the engineering process to dynamically invoke one of the alternative Web services through the run-time process brokering. Further, the paper presents how to support collaboration over the running process using conversation policy . [ABSTRACT FROM AUTHOR]

Purpose: There is a high demand on spinal surgery in patients with Parkinson's disease (PD) but the results are sobering. Although detailed clinical and radiological diagnostics were carried out with great effort and expense, the biodynamic properties of the spine of PD patients have never been considered. We propose a noninvasive method to quantify the impairment of motion abilities in patients with PD. Methods: We present an analytical cross-sectional study of 21 patients with severe PD. All patients underwent a biodynamic assessment during a standardized movement-choreography. Thus, individual spinal motion profiles of each patient were objectively assessed and compared with a large comparative cohort of individuals without PD. Moreover, clinical scores to quantify motor function and lumbar back pain were collected and X-ray scans of the spine in standing position were taken and analysed. Results: Biodynamic measurement showed that 36.9% of the assessed motions of all PD patients were severely impaired. Men were generally more functionally impaired than women, in 52% of all motion parameters. The neurological and radiological diagnostics recorded pathological values, of which UPDRS-III ON correlated with findings of the biodynamics assessment (R = 0.52, p = 0.02). Conclusions: The decision to operate on a PD patient's spine is far-reaching and requires careful consideration. Neurological and radiological scores did not correlate with the biodynamics of the spine. The resulting motion profile could be used as individual predictive factor to estimate whether patients are eligible for spinal surgery or alternative therapies. [ABSTRACT FROM AUTHOR]

Current systems for enacting scientific experiments, and simulation workflows in particular, do not support multi-scale and multi-field problems if they are not coupled on the level of the mathematical model. To address this deficiency, we present an approach enabling the trial-and-error modeling and execution of multi-scale and/or multi-field simulations in a top-down and bottom-up manner which is based on the notion of choreographies. The approach defines techniques for composing data-intensive, scientific workflows in more complex simulations in a generic, domain-independent way and thus provides means for collaborative and integrated data management using the workflow/process-based paradigm. We contribute a life cycle definition of such simulations and present in detail concepts and techniques that support all life cycle phases. Furthermore, requirements on a respective software system and choreography language supporting multi-scale and/or multi-field simulations are identified, and an architecture and its realization are presented. [ABSTRACT FROM AUTHOR]