1. Endoscopic full-thickness resection of colonic submucosal tumors originating from the muscularis propria: an evolving therapeutic strategy.
- Author
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Meidong Xu, Xiao-YunWang, Ping-Hong Zhou, Quan-Lin Li, Yiqun Zhan, Yunshi Zhong, Weifeng Chen, Lili Ma, Ishaq, S., Wenzheng Qin, Jianwei Hu, and Liqing Yao
- Subjects
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COLECTOMY , *ENDOSCOPY , *TUMORS , *PERITONITIS , *SURGICAL excision - Abstract
Endoscopic resection of colonic submucosal tumors (SMTs) is challenging and carries a high risk of perforation. In this prospective pilot study we aimed to evaluate the feasibility, safety, and efficacy of endoscopic full-thickness resection of colonic SMTs. The study enrolled 19 consecutive patients with colonic SMTs 3cmin size or smaller. In 18 of the 19 patients full-thickness resection was carried out endoscopically with the entire tumor capsule intact. In 16 of these18 patients, fullthickness resection was carried out and the colonic wall defect closed all endoscopically; in the other 2 patients, laparoscopic closure was needed. Two cases of local peritonitis were managed with conservative treatment. No deaths occurred within 30 days, and no recurrence was detected after a median of 18 months' follow-up. Endoscopic full-thickness resection is a novel method enabling resection of colonic SMTs. The colonic wall mucosal defect can be closed endoscopically in the majority of cases. It appears to be a safe and effective endoscopic technique for managing these tumors, which traditionally are managed by colonic resection. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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