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Abstract: In order to evaluate effects of exposure to mercury (tHg) and methylmercury (MeHg) of Hong Kong residents via consumption of fish, total and bioaccessible concentrations of tHg and MeHg were measured in 10 freshwater and 10 marine fishes collected from markets in Hong Kong. Concentrations of tHg and MeHg in fishes ranged from 27.2 to 311ngg−1 (median 88.9ngg−1) and ND to 116ngg−1 (median 45.0ngg−1), respectively. Concentrations of MeHg in marine fishes (64.4±28.5ngg−1) were significantly greater than those in freshwater fishes (40.3±26.0ngg−1). Bioaccessibility tHg and MeHg was predicted for edible flesh of twenty fishes by use of an in vitro gastrointestinal assay. Bioaccessibilities of tHg and MeHg ranged from 21.4 to 51.7% (mean 37.4%) and 19.5 to 59.2% (mean 43.7%), respectively. Based on total concentrations, diets of 36% of adults and 51% of children exceeded the reference dose (RfD, 100ngkg−1 bodymass(bm)d−1) for MeHg, but when bioaccessibility was considered, consumption of local market fish would not result in an EDIbio exceeded the RfD of MeHg for Hong Kong adults. These contradictory results suggested that risk assessments based on total concentrations would overestimate exposure because not all of contaminants consumed are bioaccessible. Furthermore, 9% of children had EDIbio for MeHg that exceeded the RfD, which suggests that more attention should be paid to consumption of local fish on health and development of children in Hong Kong. [Copyright &y& Elsevier]

The article presents announcement regarding upcoming symposiums and congresses related to the biology of the skin. The 41st Annual Symposium on the Biology of the Skin will be held at Snowmass Village, Colorado, July 25-29, 1992. Focus of the conference will be hair biology. The 3rd Asian Dermatological Congress will be held January 15-17, 1993 at the Hong Kong Convention and Exhibition Centre in Hong Kong, China, a joint venture of the Hong Kong Society of Dermatology & Venereology and the Asian Dermatological Association.