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Start Over Descriptor "Anaerobiosis" Topic anaerobic growth Database Academic Search Index Publisher academic press inc.

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1 results on '"Anaerobiosis"'

1. Distinct physiological roles for the two l-asparaginase isozymes of Escherichia coli.

Author

Srikhanta, Yogitha N., Atack, John M., Beacham, Ifor R., and Jennings, Michael P.

Subjects
*ASPARAGINASE, *ISOENZYMES, *ESCHERICHIA coli enzymes, *ENZYME kinetics, *ENZYME regulation, *ANAEROBIOSIS, *CYCLIC adenylic acid
Abstract

Highlights: [•] Escherichia coli contains two l-asparaginase isozymes with distinct localization, kinetics and regulation. [•] Mutant strains were used to examine the roles of these enzymes in l-asparagine utilization. [•] We report that l-asparaginase II permits growth on asparagine and glycerol under anaerobic conditions. [•] We propose that this enzyme is the first step in a co-regulated pathway leading to fumarate. [•] The pathway is regulated by anaerobiosis and cAMP and provides a terminal elector acceptor. [ABSTRACT FROM AUTHOR]

Published
2013
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