1. Two new quinazoline alkaloids produced by Aspergillus versicolor and their antimicrobial activities.
- Author
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Liao, Liang-Xiu, Huang, Jun-Guo, Liu, Qing-Pei, Yao, Ming, Wang, Wen-Jing, and Yang, Xiao-Long
- Subjects
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HETEROCYCLIC compounds , *STATISTICAL correlation , *ALKALOIDS , *NUCLEAR magnetic resonance spectroscopy , *RESEARCH funding , *DRUG resistance in microorganisms , *FUNGI , *ANTI-infective agents , *PLANT extracts , *BIOINFORMATICS , *ASPERGILLUS , *MOLECULAR structure , *RESEARCH , *SPECTRUM analysis , *COMPARATIVE studies , *DATA analysis software , *SPECTROPHOTOMETRY , *PHARMACODYNAMICS - Abstract
Two new quinazoline alkaloids versicomides G–H (1 and 2), together with seven known compounds, were isolated from Aspergillus versicolor HYQZ-215 obtained from the sediment of Qarhan Salt Lake. Their structures were elucidated by NMR, HRESIMS, and quantum chemical ECD calculations data. The antimicrobial activities of these compounds were evaluated against seven agricultural pathogenic fungi and eight clinically drug-resistant bacteria. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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