Search

Background: Combining treatment modalities for fat disruption and body shaping has been frequently performed to achieve a synergistic effect. These modalities are usually used with time intervals between treatments due to safety concerns. Focused ultrasound is a well-known method to disrupt fat tissue. This technology has a high safety proile when using cavitation effect as opposed to a thermal effect. Objective: To prove that treating with focused ultrasound technology and radiofrequency in one session is safe and can achieve meaningful results. Patients and method: Twenty-four subjects were treated in the abdo- men during a single session which included radiofrequency treatment (Reaction™, VIORA) immediately before and after a treatment with non-thermal focused ultrasound (Contour I, UltraShape™). Two ultra-sound treatment protocols were used, each in 12 subjects. Subjects were evaluated at day 7, 14 and 28 after the day of treatment. Safety variables included adverse event collection for the whole study population and clinical laboratory evaluation in 12 subjects. Primary eficacy variables included circumference measurements. Results: Only one mild adverse event was reported and was attributed to faulty operation of the radiofrequency device. Lab tests were normal throughout the study. At 28 days, combined ultrasound-radiofrequency treatment resulted in mean circumference reductions of 3 and 3.4 cm depending on the ultrasound protocol used; 93% of subjects experi- enced a circumference reduction greater than 1.5 cm. Conclusions: Focused ultrasound combined with radiofrequency, in one treatment session to disrupt fat tissue for the purpose of body contouring, is safe, effective and well tolerated. [ABSTRACT FROM AUTHOR]