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This theoretical essay aims to investigate how Practice-Based Studies (PBS) contribute to the understanding of Open Innovation (OI). We used a literature review about these themes. We sought to reflect on the assumptions, concepts, definitions and elements that constitute the PBS and OI After studying both approaches, it was possible to verify that OI can be understood through the epistemological assumptions of PBS, considering the great diversity of possible actions involved to OI, organized by structures and surrounded by material arrangements. Possible identified practices are evidenced when considering the search for external knowledge, the interactive relationships between the agents involved, the commercialization of inventions covering the generation and acquisition of ideas, the selection and decision-making practices on the best ideas and partners for the productive arrangements and practices that occurred later, involving planning practices, new techniques, new products and new services. [ABSTRACT FROM AUTHOR]