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• A dynamic climate change impact evaluation framework is proposed. • Bamboo bio-concrete is a good climate change mitigation and adaptation alternative. • Bamboo bio-concrete presents a reliable carbon-thermal energy solution. • Bamboo bio-concrete provides a promising alternative for developing countries. This study aims to present a framework to quantify the climate change impact during the buildings' life cycle. The proposed framework is tested on a bamboo bio-concrete (BBC) building and compared with conventional constructive systems, in a Brazilian housing project considering six cities using Dynamic Life Cycle Assessment (DLCA) and thermal energy simulation. The increase of BBC in the building envelope, from 10 cm to 20 cm, leads to the improvement of carbon stock and reduces operational carbon. The BBC can be considered a potential alternative for climate change mitigation and adaptation and developed where bamboo is an available source. [ABSTRACT FROM AUTHOR]