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Nanoparticles are extensively used in industrial products or as food additives. However, despite their contribution to improving our quality of life, concerns have been raised regarding their potential impact on occupational and public health. To speed up research assessing nanoparticle-related hazards, this study was undertaken to identify early markers of harmful effects on the lungs. Female Sprague Dawley rats were either exposed to crystalline silica DQ-12 with instillation, or to titanium dioxide P25, carbon black Printex-90, or multi-walled carbon nanotube Mitsui-7 with nose-only inhalation. Tissues were collected at three post-exposure time points to assess short- and long-term effects. All particles induced lung inflammation. Histopathological and biochemical analyses revealed phospholipid accumulation, lipoproteinosis, and interstitial thickening with collagen deposition after exposure to DQ-12. Exposure to the highest dose of Printex-90 and Mitsui-7, but not P25, induced some phospholipid accumulation. Comparable histopathological changes were observed following exposure to P25, Printex-90, and Mitsui-7. Comparison of overall gene expression profiles identified 15 potential early markers of adverse lung outcomes induced by spherical particles. With Mitsui-7, a distinct gene expression signature was observed, suggesting that carbon nanotubes trigger different toxicity mechanisms to spherical particles. [ABSTRACT FROM AUTHOR]

Among the different air pollutants, particulate matter (PM) is of great concern due to its abundant presence in the atmosphere, which results in adverse effects on the environment and human health. The different components of PM can be classified based on their physicochemical properties. Carbonaceous particles (CPs) constitute a major fraction of ultrafine PM and have the most harmful effects. Herein, we present a detailed overview of the main components of CPs, e.g., carbon black (CB), black carbon (BC), and brown carbon (BrC), from natural and anthropogenic sources. The emission sources and the adverse effects of CPs on the environment and human health are discussed. Particularly, we provide a detailed overview of the reported toxic effects of CPs in the human body, such as respiratory effects, cardiovascular effects, neurodegenerative effects, carcinogenic effects, etc. In addition, we also discuss the challenges faced by and limitations of the available analytical techniques for the qualitative and quantitative detection of CPs in atmospheric and biological samples. Considering the heterogeneous nature of CPs and biological samples, a detailed overview of different analytical techniques for the detection of CPs in (real-exposure) biological samples is also provided. This review provides useful insights into the classification, toxicity, and detection of CPs in biological samples. [ABSTRACT FROM AUTHOR]

In this work, polymer matrix composites with the compositions PTFE/KFTO(H) and PTFE/KFTO(H)@CB and with filler volume fractions of 2.5, 5.0, 7.5, 15, and 30% (without and with carbon modification at a content of 2.5 wt.% regarding ceramic material) were produced by calendering and hot pressing and studied using FTIR, SEM, and impedance spectroscopy methods. Ceramic filler (KFTO(H)) was synthesized using the sol–gel Pechini method. Its structure was investigated and confirmed by the XRD method with following Rietveld refinement. The carbon black (CB) modification of KFTO(H) was carried out through the calcination of a mixture of ceramic and carbon materials in an argon atmosphere. Afterwards, composites producing all the components' structures weren't destroyed according to the FTIR results. The effect of carbon additive at a content of 2.5 wt.% relating to ceramic filler in the system of polymer matrix composites was shown, with permittivity increasing up to ε' = 28 with a simultaneous decrease in dielectric loss (tanδ < 0.1) at f = 103 Hz for composites of PTFE/KFTO(H)@CB (30 vol.%). [ABSTRACT FROM AUTHOR]

In this work, we evaluated the processing and reinforcement characteristics of both carbon black (CB) and graphene nanoplatelets (GNPs) within a nitrile butadiene rubber (NBR) matrix. The aspect ratio of the GNPs was measured using atomic force microscopy (AFM) and related to the dispersion and agglomeration within the NBR matrix, as observed by scanning electron microscopy (SEM). The relationship between GNP aspect ratio and mechanical properties was studied by micromechanical modelling. The tensile and tear properties of NBR after compounding with GNPs were enhanced to a greater extent compared to carbon black, while curing times were smaller and scorch times longer, indicating some of the advantages of using GNPs. Overall, the inherent properties of GNPs along with their geometry led to the production of better-performing rubber compounds that can replace their CB-filled counterparts in applications where flexibility, tear strength and compliance are important. The influence of processing on dispersion, orientation and agglomeration of flakes was also highlighted with respect to the Young's modulus of the NBR compounds. [ABSTRACT FROM AUTHOR]

A new voltametric method for highly sensitive propranolol (PROP) determination was developed. A glassy carbon electrode modified with a hybrid material made of carbon black (CB) and Nafion was used as the working electrode. The preconcentration potential and time were optimized (550 mV and 15 s), as well as the supporting electrolyte (0.1 mol L−1 H2SO4). For 15 s preconcentration time, linearity was achieved in the range 0.5–3.5 μmol L−1 and for 120 s in 0.02–0.14 μmol L−1. Based on the conducted calibration (120 s preconcentration time) limit of detection (LOD) was calculated and was equal to 7 nmol L−1. To verify the usefulness of the developed method, propranolol determination was carried out in real samples (tablets and freeze-dried urine). Recoveries were calculated and were in the range 92–102%, suggesting that the method might be considered as accurate. The repeatability of the signal expressed as relative standard deviation (RSD) was equal to 1.5% (n = 9, PROP concentration 2.5 µmol L−1). The obtained results proved that the developed method for propranolol determination might be successfully applied in routine laboratory practice. [ABSTRACT FROM AUTHOR]

A facile strategy is proposed to synthesize boron-doped ECP600 carbon black (B-ECP600), and the catalyst of Pt supported on boron-doped ECP600 (Pt/B-ECP600) shows smaller particle sizes and a higher electrochemical surface area (95.62 m2·gPt−1) and oxygen reduction reaction activity (0.286 A·mgPt−1 for mass activity; 0.299 mA·cm−2 for area specific activity) compared to the catalyst of Pt supported on ECP600 (Pt/ECP600). The results show that the boron doping of the carbon supports plays an important role in controlling the size and dispersion of Pt nanoparticles and the O2 adsorption/dissociation of the oxygen reduction reaction. A further accelerated durability test proves that boron doping can greatly enhance the stability of carbon support and thus improves the electrochemical performance of the catalyst during the long-time running. All these results suggest boron-doped carbon has great potential for application in fuel cells. [ABSTRACT FROM AUTHOR]