1. Two highly acetylated sterols from the marine sponge Dysidea sp.
- Author
-
Lu, Yu and Zhao, Ming
- Subjects
- *
STEROLS , *SPONGES (Invertebrates) , *SPECTRUM analysis , *NUCLEAR magnetic resonance , *ANTI-infective agents - Abstract
Two new highly acetylated steroids, named dysiroid A ( 1) and dysiroid B ( 2), together with a known compound ( 3) were isolated from the marine sponges Dysidea sp. The chemical structures of 1 and 2 were elucidated by spectroscopic analyses including 1D and 2D NMR experiments and high-resolution electrospray impact mass spectroscopy. Their in vitro antimicrobial activities against a panel of bacterial strains were evaluated. Compounds 1 and 2 showed potent activity against some of the strains with minimum inhibitory concentrations ranging from 4 to 8 μg mL−1. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF