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The plant Carapa guianensis is used empirically for the treatment of dermatological diseases against inflammatory processes. The present study aimed at evaluating the healing of open skin lesions in Wistar rats treated with the C. guianensis oil. Two incisions were made on the back of the animals and the wounds were treated with the C. guianensis oil at 50% (A50) and 20% (A20). The control group (CG) received a treatment with vaseline. The wounds were treated daily and clinical, morphological and histological evaluations were performed on the fourth, seventh, 14th and 21st days of treatment and the tensiometric study on the 21st day. The biochemical profile of the animals was also assessed after 21 days of treatment. It was observed that the use of C. guianensis showed similar results to the ones of the control group in the evaluations, but in the tensiometry, the concentration A20 group presented lower tension when compared to the other groups. Regarding the biochemical parameters, the AST enzyme of the A50 group showed higher values in relation to the control group. It was possible to conclude that the C. guianensis oil shows similar results to the vaseline in wound healing, especially at a concentration of 50%. This study also showed a possible biological interference of the C. guianensis oil on the AST enzyme. [ABSTRACT FROM AUTHOR]

In order to know the effects of application of honey to wounds (that is, in their healing process), the following question was formulated: "How does the application of honey to wounds contribute to their treatment?". To carry out the work, the seven steps in the Cochrane Handbook were followed. Using this process, it was possible to assemble a set of studies that followed the previously-defined criteria for inclusion and exclusion. The analysis showed that honey can be beneficial in the healing of wounds; however, no definitive conclusions are possible. This review opens doors for further research to be undertaken in this area. [ABSTRACT FROM AUTHOR]

The aim of the study was to compare the effectiveness of Cissus quandrangularis and Phyllanthus reticulatus poir in healing at induced wound in guinea pigs skin. Were used 12 guinea pigs, male, Abyssinian, with 6 months old and weighing 550 to 850g. Three groups of four animals were created. Once anesthetized, three surgical wounds were performed on each animal. The F1 was treated with Cissus quandrangularis; F2 was group control (saline solution) and F3 with Pyllanthus reticulatus poir. Group I was euthanized on the seventh day after surgery; Group II on the fourteenth day and the Group III on the twenty-first day after surgery and the lesions submitted to histological examination. Were used SPSS®, with analysis of variance (ANOVA) followed by Tukey test at 5% of significance. The lesions treated with Cissus quandrangularis healed faster and higher than Phyllanthus reticulatus poir. [ABSTRACT FROM AUTHOR]