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2,105 results on '"INVESTIGATIONAL drugs"'

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1. A Pilot Study: Treatment of High Alcohol Consumption in a Novel Minipig Model of Alcohol Use Disorder.

2. Novel Drug-Drug Interaction of Potential Rifabutin-Induced Edoxaban Failure: A Case Report.

3. Investigation through naphtho[2,3‐a]pyrene on mutated EGFR mediated autophagy in NSCLC: Cellular model system unleashing therapeutic potential.

4. Pharmaceutical Therapies for Pediatric Respiratory Disease: Setbacks and Progress in 2024.

5. Treating Hypercholesterolemia in Older Adults for Primary Prevention of Cardiovascular Events.

6. Updates on Therapeutic Strategies in the Treatment of Relapsed/Refractory Multiple Myeloma.

7. Medicines for an aging population: The EMA perspective and policies.

8. Current status of inclusion of older groups in evaluations of new medications: Gaps and implementation needs to fill them.

9. Closing the gap: A United States perspective on enhancing drug evaluation in older adults.

10. Value of Assessing 1‐Hydroxymidazolam in Drug‐Drug Interaction Studies with Midazolam as a Substrate of Cytochrome P450 3A.

11. A novel sequential treatment approach between denosumab and romosozumab in patients with severe osteoporosis.

12. Evaluation of a pharmacist-led workflow for the FDA Expanded Access Program.

13. Inhibition of falcilysin from Plasmodium falciparum by interference with its closed-to-open dynamic transition.

14. Real‐World Evidence Application in Translational Medicine: Making Use of Prescription Claims to Inform Drug–Drug Interactions of a New Psoriasis Treatment.

15. Progress report on new medications for seizures and epilepsy: A summary of the 17th Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVII). II. Drugs in more advanced clinical development.

16. Study of Biological Effects Induced in Solid Tumors by Shortened-Duration Thermal Ablation Using High-Intensity Focused Ultrasound.

17. Early-Stage Non-Small Cell Lung Cancer: New Challenges with Immune Checkpoint Blockers and Targeted Therapies.

18. Preclinical Efficacy of VTX-0811: A Humanized First-in-Class PSGL-1 mAb Targeting TAMs to Suppress Tumor Growth.

19. Synthesis of Natural and Sugar-Modified Nucleosides Using the Iodine/Triethylsilane System as N -Glycosidation Promoter.

20. Recent and anticipated novel drug approvals (Q2 2024 through Q1 2025).

21. New Investigational Drug's Targeting Various Molecular Pathways for Treatment of Cervical Cancer: Current Status and Future Prospects.

22. The evolving regulatory system of advanced therapy medicinal products in China: a documentary analysis using the World Health Organization Global Benchmarking Tool standards.

23. Evaluation of a remote hybrid staffing model for investigational drug service pharmacists.

24. Preclinical and Clinical Investigations of Potential Drugs and Vaccines for COVID-19 Therapy: A Comprehensive Review With Recent Update.

25. Standardization of key performance indicators and metrics for investigational drug services: Consensus recommendations among IDS specialists.

26. Pharmacological activity and clinical application analysis of traditional Chinese medicine ginger from the perspective of one source and multiple substances.

27. Advancements in Non-Alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis Treatment: From Lifestyle Interventions to Novel Therapies.

28. Use of cancer-directed therapy at the end of life among adolescents and young adults.

29. Pediatric Pharmacology for the Primary Care Provider: Advances and Limitations.

30. Pharmacokinetics and Safety of Firsocostat, an Acetyl‐Coenzyme A Carboxylase Inhibitor, in Participants with Mild, Moderate, and Severe Hepatic Impairment.

31. The Immunotherapy of Acute Myeloid Leukemia: A Clinical Point of View.

32. Computational Approach for the Development of pH-Selective PD-1/PD-L1 Signaling Pathway Inhibition in Fight with Cancer.

33. Composite Plot for Visualizing Aminotransferase and Bilirubin Changes in Clinical Trials of Subjects with Abnormal Baseline Values.

34. A Qualitative Interview Study on Expanded Access Clinical Trials for Compassionate Use in Japan.

35. Emerging Systemic Treatment Options in Atopic Dermatitis.

36. Natural disease course modeling of achondroplasia to evaluate the efficacy of recifercept in the absence of a placebo control arm in phase II study.

37. Successful Distribution of Tecovirimat During the Peak of the Mpox Outbreak -- Los Angeles County, June 2022-January 2023.

38. Alkynyl nicotinamides show antileukemic activity in drug-resistant acute myeloid leukemia.

39. Novel Targets and Advanced Therapies in Diffuse Large B Cell Lymphomas.

40. Improvement effects of a novel Chinese herbal formula in imiquimod and IL-23-stimulated mouse models of psoriasis.

41. Identifying therapeutic target genes for migraine by systematic druggable genome-wide Mendelian randomization.

42. Prevention of paclitaxel-induced peripheral neuropathy: literature review of potential pharmacological interventions.

43. Cardiovascular disease, medication regimens and HIV in pregnancy: new research relevant to nurses 1.

44. Critically explaining British policy responses to novel psychoactive substances using the policy constellations framework.

45. Design and Construction of a Radiochemistry Laboratory and cGMP-Compliant Radiopharmacy Facility.

46. A Clinical Perspective on Plasma Cell Leukemia: A Single-Center Experience.

47. Assessing expectancy and suggestibility in a trial of escitalopram v. psilocybin for depression.

48. The Benefits and Risks of Receiving Investigational Solid Tumor Drugs in Randomized Trials: A Systematic Review and Meta-analysis.

49. Guideline for evaluating the effects of psychotropic drugs on motor vehicle driving performance in Japan: A tiered approach for the assessment of clinically meaningful driving impairment.

50. Drug release profile of a novel exenatide long-term drug delivery system (OKV-119) administered to cats.

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