1. Essential Oil Composition and Antimicrobial Activity of Angelica archangelica L. (Apiaceae) Roots.
- Author
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Fraternale, Daniele, Flamini, Guido, and Ricci, Donata
- Subjects
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MEDICINAL plants , *ALTERNATIVE medicine , *ANTI-infective agents , *CANDIDA albicans , *CLOSTRIDIOIDES difficile , *DOSE-effect relationship in pharmacology , *ENTEROCOCCUS , *ESSENTIAL oils , *MICROBIAL sensitivity tests , *PLANT roots , *PLANT extracts , *DESCRIPTIVE statistics , *IN vitro studies , *PHARMACODYNAMICS - Abstract
In this paper, the chemical composition and the antimicrobial activity of the essential oil of Angelica archangelica L. (Apiaceae) roots from central Italy were analyzed. The major constituents of the oil were α-pinene (21.3%), δ-3-carene (16.5%), limonene (16.4%) and α-phellandrene (8.7%). The oil shows a good antimicrobial activity against Clostridium difficile, Clostridium perfringens, Enterococcus faecalis, Eubacterium limosum, Peptostreptococcus anaerobius, and Candida albicans with minimum inhibitory concentration (MIC) values of 0.25, 0.25, 0.13, 0.25, 2.25, and 0.50% v/v, respectively. A weaker antimicrobial activity against bifidobacteria and lactobacilli-very useful in the intestinal microflora-has also been shown with MIC values >4.0% v/v. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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