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Abstract: This study attempted to estimate the elastic modulus of cortical specimens directly from the computed tomography (CT) number (CT). Cubic specimens of fresh bovine femora were tested under compressive loading. The corresponding three-dimensional mesh models of these specimens were established with the aid of CT images. The elastic modulus of each element was determined using the following transfer formula: E=A×(CT)B. The A and B were determined by matching the simulation results with the experimental force–displacement curves. An optimization approach was used to match the entire specimen sets between simulations and experiments. The results indicated that the elastic modulus of cortical bone can be effectively estimated using a power relationship (E=1.26×10−3×(CT)1.93) directly from the CT number. This procedure eliminates the need to determine the bone density, and therefore reduces the computational time required to define mechanical properties in finite element methods. [Copyright &y& Elsevier]

Abstract: One of the major causes of loosening of cementless acetabular cup implants is insufficient initial stability. This study used three-dimensional finite element models of the pelvis and acetabular components to investigate the effects of the number of screws, bone quality, and friction coefficient of the acetabular cup on the initial stability under normal walking. A commercially available hemispherical acetabular cup with five screw holes was used as the default model. The stiffness of the pelvis and the friction coefficient of the cup were systematically varied, within a realistic range, to assess the initial stability of the acetabular cup. The simulations showed that the inserted screws provide only a localized reduction in the relative micromotion between the cup and pelvis therefore inserting several screw closed together might not be useful. Changes in the pelvic stiffness have a non-linear effect on the initial stability of acetabular cup and the subchondral bone provides good support for fixation of the cementless cup. The friction coefficient of the acetabular cup plays a limited role, comparing with the factor of bone quality, in resisting relative micromotion in the cup–pelvis interface. [Copyright &y& Elsevier]

Abstract: One of the major causes inducing loosening in the cementless acetabular cup implanting is its insufficient initial stability. In this study, three-dimensional finite element models of the pelvis and acetabular components were developed to investigate the relationship between relative micromotion, initial stability, and screw fixation under six daily activity loadings. A commercial available hemispheric cup with five screw holes was used as the target acetabular cup. The simulation results showed that if screws were placed closed together, when the screw number increased from 1 to 5, the peak micromotion decreased less than 14%, from 126.5 to 108.8μm, while the stable region, micromotion less than 28μm, enlarged only by 40%, from 46.1% to 64.7%. However, if the screw could be placed near the cup rim, a single rim screw, 202.1μm micromotion, could provide better stability than that of four dome screws, 209.6μm micromotion, placed closed together. To conclude, multiple cup screws should be placed near cup rim and as separate as possible to enlarge the stable region and reduce the peak micromotion between cup and acetabulum. [Copyright &y& Elsevier]