1. Pyrimethaminium sulfosalicylate monohydrate.
- Author
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Hemamalini, Madhukar, Muthiah, Packianathan Thomas, Sridhar, Balasubramanian, and Rajaram, Ramaswamy Karunanandam
- Subjects
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HYDRATES , *SALICYLATES , *PYRIMIDINES , *MOLECULAR structure , *HYDROGEN bonding , *CRYSTALLOGRAPHY - Abstract
In the crystal structure of the title compound, 2,4-diamino-5-(4-chlorophenyl)-6-ethylpyrimidin-1-ium 3-carboxy-4-hydroxybenzenesulfonate monohydrate, C12H14ClN4+·C7H5O6S−·H2O, the asymmetric unit contains two crystallographically independent protonated pyrimethamine (PMN) molecules, a pair of sulfosalicylate anions and two water molecules. Both the PMN molecules are protonated at one of the pyrimidine N atoms. The component species interact through numerous intermolecular N—H⋯O, N—H⋯N and O—H⋯O hydrogen bonds and C—H⋯O interactions. [ABSTRACT FROM AUTHOR]
- Published
- 2005
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