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[Display omitted] Calcium (Ca2+) acts as a second messenger and constitutes a complex and large information exchange system between the endoplasmic reticulum (ER) and mitochondria; this process is involved in various life activities, such as energy metabolism, cell proliferation and apoptosis. Increasing evidence has suggested that alterations in Ca2+ crosstalk between the ER and mitochondria, including alterations in ER and mitochondrial Ca2+ channels and related Ca2+ regulatory proteins, such as sarco/endoplasmic reticulum Ca2+-ATPase (SERCA), inositol 1,4,5-trisphosphate receptor (IP3R), and calnexin (CNX), are closely associated with the development of kidney disease. Therapies targeting intracellular Ca2+ signaling have emerged as an emerging field in the treatment of renal diseases. In this review, we focused on recent advances in Ca2+ signaling, ER and mitochondrial Ca2+ monitoring methods and Ca2+ homeostasis in the development of renal diseases and sought to identify new targets and insights for the treatment of renal diseases by targeting Ca2+ channels or related Ca2+ regulatory proteins. [ABSTRACT FROM AUTHOR]

• 90 NAC transcription factors (TFs) were identified in the eggplant genome. • Conserved motifs, conserved domains and gene structure of SmNAC genes were resolved. • Chromosomal location, gene replication and synteny of SmNAC genes were investigated. • Expression patterns of SmNAC genes were analyzed in vegetative and reproductive organs, at different developmental stages. • qRT-PCR analyses of ATAF subfamily members, exhibited a large diversity in the regulation of different abiotic stresses. NAC proteins, as one of the largest plant-specific transcription factors, play key roles in plant growth, development process, and various abiotic/biotic stresses. In this study, 90 NAC transcription factors (TFs) were identified in the eggplant genome, among them, 80 NAC genes from eggplant (SmNAC) were anchored unevenly in 12 chromosomes, but 10 SmNAC genes were mapped on unanchored scaffolds. Phylogenetic analysis indicated that only fifty-nine SmNAC genes were divided into 14 different subfamilies. Gene structure analysis revealed that the number of exons ranged from 1 to 16. Motif analysis revealed that the identified SmNAC transcription factors included the conserved NAC domain and motif2 was the conserved motif. In aspects of gene duplication analysis, five pairs of tandem replications and three pairs of fragment replications were identified in eggplant genome. Subsequently, 49 SmNAC genes were collinear with NAC genes from Arabidopsis or tomato, moreover, seven SmNAC genes were collinear with NAC genes in other two species. In addition, expression patterns of SmNAC genes were analyzed in vegetative and reproductive organs, at different developmental stages. Nine genes were not expressed in all of the examined developmental stages, 36 SmNAC genes were ubiquitously expressed in all eggplant organs/tissues, but differentially expressed in different tissues, and other 45 SmNAC genes detected in some tissues declared their involvement in the growth and development of certain tissues. Following further qRT-PCR analysis of SmNAC19, SmNAC31 and SmNAC75 , belonging to ATAF subfamily, exhibited a large diversity in expression patterns, indicating their involvement in the regulation of different abiotic stresses. This study would help to further understand and enrich the physiological function of the SmNAC gene family in eggplant, and could provide high-quality genetic resources for eggplant genetics and breeding. [ABSTRACT FROM AUTHOR]