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1. A Breath-activated, Precision Bolus Injection System for Human Inhalation-exposure and Drug Delivery Studies.

Author

Gunarathne, G. P. P., Koujalagi, V., Semple, S., and Ayres, J. G.

Subjects
*DRUG delivery systems, *MEDICAL informatics, *DRUG delivery devices, *BIOADHESIVE drug delivery systems, *RESPIRATORY organs
Abstract

This paper presents the work carried out in developing a precision, bolus injection system to study the effect of regional deposition of fine particulate matter (PM) within the human respiratory system and to investigate the optimal conditions for inhaled drug delivery. In contrast to existing methods, the new system computes parameters necessary and injects PM into breath cycles by a process of dynamic breadth pattern analysis and statistical data relating to stored PM to achieve a highly controlled delivery within specified exposure times and intervals. [ABSTRACT FROM AUTHOR]

Published
2007

2. Sidestream Smoke.

Subjects
*DEFINITIONS, *SMOKE, *CIGARETTES, *DIFFUSION, *AIR pollution
Abstract

A definition of the term "sidestream smoke" is presented. It refers to the material which diffuses through the paper plus the material released into the air from the burning tip of the cigarette.

Published
2001